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Waters 2487 dual specifications

On the other hand, a particular protein function can be realized with different protein folds, and an example of this are protein phosphatases. Protein phosphatases feature two distinctively different catalytic mechanisms for hydrolytically cleaving phosphorylated amino acid residues. The active sites of serine/threonine protein phosphatases (PPs) contain two metal centers that directly activate a water molecule for nucleophilic attack of the phosphate ester bond. In contrast, protein tyrosine phosphatases (PTPs) [105] possess a Cys residue present in the active site loop containing the conserved PTP signature motif HCXXXXXRS. The Cys sidechain acts as the attacking nucleophile in the formation of a phosphocysteine intermediate, which is eventually hydrolyzed by a water molecule [106], The same catalytic mechanism is also shared by dual-specificity phosphatases (see below). [Pg.115]

Because the system likely is nonisothermal, the analysis of a closed-desiccant system requites knowledge of the temperature of the desiccant as well as the dew point (ice point) or water concentration (partial pressure) specification. Indeed, the whole system may undergo periodic temperature transients that may compHcate the analysis. Eor example, in dual-pane windows the desiccant temperature is approximately the average of the indoor and outdoor temperatures after a night of cooling. However, after a day in the sun, the desiccant temperature becomes much warmer than the outdoor temperature. When the sun sets, the outdoor pane cools quickly while the desiccant is still quite warm. The appropriate desiccant for such an appHcation must have sufficient water capacity and produce satisfactory dew points at the highest temperatures experienced by the desiccant. [Pg.509]

Specifically note that Type 7 (explosion-proof) enclosures and their associated conduit systems are neither gas or liquid tight. Consequently, corrosive gases such as hydrogen sulfide and water from rain or internal condensation can accumulate with the enclosure. Premature failure of electrical devices and interconnections often results when preventive measures such as drains, air purges, and dual rated enclosures are not used to remove or exclude these corrosive elements. Type 7 enclosures are intended for indoor use. [Pg.270]

Humidity has a significant influence on the photocatalytic oxidation of aromatic contaminants in the gas phase. This is of particular interest, because commercial photocatalytic systems will be required to operate under a broad range of relative-humidity levels. The specific influence of relative humidity on the photocatalytic reaction has generally proved rather difficult to quantify because water has a dual role It may compete with contaminants for surface adsorption sites (a negative influence) and it plays a role in the regeneration of surface hydroxyl groups during photocatalysis (a positive influence). [Pg.263]

Paticlc sizes of 7-10 p can be removed without a filter aid Dual flow filter. A dual flow filter is a modi tied veision ot a multimedia filter. The media are arranged by particle size and specific gravitv for simultaneous up and downtlovv nitration Filtered water leaves through an outlet in the middle of the bed. Coarse-to-fine filtration occurs in both directions. [Pg.187]

Pederson described a specific HPLC method for the determination of dipyridamole in serum [74]. The HPLC system used was a Waters model 600 liquid chromatograph equipped with a U6K injector, a pBondapak Ci8 column (30 cm x 39 mm) (10 pm), and a model 440 dual channel filter absorbance detector in conjunction with a Tarkan W + W 600 recorder. The mobile phase was a 75 25 mixture of methanol and a 0.02 M solution of sodium acetate (adjusted to pH 4 with acetic acid). The solvent flow rate of 2 mL/min was produced by an applied pressure of approximately 2000 p.s.i. Detection of the analyte was made at the UV absorption maximum of 280 nm. [Pg.271]

Additional experiments have been conducted that varied A from 0.7 to 3.0, holding all other feed conditions constant.8 Dual steady-state operation was observed for the entire range tested providing more evidence that the water amount in the feed composition is probably the dominant factor. This type of experiment was repeated for a different CO feed concentration and nearly the same behavior was recorded. This dual steady-state nature persists for a wide range of lambda, which points to the fact that dual steady state is more influenced by feed composition and more specifically by water amount. Since water has high heat capacity, this may temper the heat rise and delay the onset of H2 oxidation reaction. [Pg.339]

The associative mechanism of thickening has been variously described, but is generally thought to result from nonspecific hydrophobic association of water-insoluble groups in water-soluble polymers 34, 35). For associative ASTs, the terminal hydrophobes of the ethoxylated side chains are considered to be the primary interactive components. These hydrophobes can interact with each other via intermolecular association, and can also interact with hydrophobic particle surfaces when present. The specific interaction with dispersed-phase components such as latex particles has been shown to be one of surface adsorption (36). In essence, the associative component of thickening in dispersed-phase systems also has dual character resulting from the building of structure within the aqueous phase and interaction with particle surfaces. [Pg.467]

As in the ease of protein hydration, water moleeules again play a dual role. First and foremost, they provide stability to the observed nueleie aeid conformation. Second, they stabilize, often for a long duration, complexes with diverse proteins and intercalators. In the latter cases, localized ordered water molecules facilitate formation of specific nucleic acid stmctures around external molecules/groups [3]. The detailed structural morphology of the DNA hydration stmcture is illustrated in Appendix 10. A. [Pg.153]


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