Larva migrans visceral

Toxocara canis Dog roundworm disease, visceral larva migrans... 

Beaver, P.C. (1962) Toxocarosis (visceral larva migrans) in relation to tropical eosinophilia. Bulletin de la Societe de Pathologie Exotique 55, 555—576. 

Nichols, R.L. (1956) The etiology of visceral larva migrans. I. Diagnostic morphology of infective second-stage Toxocara larvae. Journal ofParasitology 42, 349-362. 

Several benzimidazoles are in use for the treatment of helminthic infections. Three of these, mebendazole, thiabendazole and albendazole, are described in this section. They have a broad range of activity against many nematode and cestode parasites, including cutaneous larva migrans, trichinosis, disseminated strongyloidiasis, and visceral larva migrans. A fourth, triclabendazole, is considered as the drug of choice for Easciola hepatica therapy. 

Mebendazole is used primarily for the treatment of A. lumbricoides, T. trichiura, E. vermicularis, and hookworm infections, in which it produces high cure rates. It is an alternative agent for the treatment of trichinosis and visceral larva migrans. Owing to its broad-spectrum anthelmintic effect, mixed infections (ascariasis, hookworm infestation, or enterobiasis in association with trichuriasis) frequently respond to therapy. High doses have been used to treat hydatid disease, but albendazole is now thought to be superior. 

Visceral larva migrans PO 50 mg/kg/day ql2h for 7 days. Maximum 3 g/day. 

Nakamura, N., Kiuchi, F., Tsuda, Y. and Kondo, K. (1988) Studies on crude drugs effective on visceral larva migrans. V. The larvicidal principle in mace (aril of Myristica fragrans). Chemical and Pharmacological Bulletin 36(7), 2685. 

Bhatla, V., Sarin, S.K. Hepatic visceral larva migrans evolution of the lesion, diagnosis, and role of high-dose albendazole therapy. Amer. J. Gastroenterol. 1994 89 624-627... 

Hartleb, M., Januszewski, K. Severe hepatic involvement in visceral larva migrans. Eur. J. Gastroenterol. Hepatol. 2001 13 1245-1249... 

Kaplan, K.J., Goodman, Z.D., Ishak, K.G. Eosinophilic granuloma of the hver. A characteristic lesion with relationship to visceral larva migrans. Amer. J. Surg. Path. 2001 25 1316-1321... 

Zlnkham, W.H. Visceral larva migrans. A review and reassessment indicating two forms of clinical expression visceral and ocular. Amer. J. Dis. Child. 1978 132 627-633... 

A 38-year-old woman with cough, eosinophUia, and pulmonary infiltrates due to visceral larva migrans from Toxocara canis infection took albendazole 600 mg for 8 weeks and developed sUght transient skin eruptions (35). 

Inoue K, Inoue Y, Arai T, Nawa Y, Kashiwa Y, Yamamoto S, Sakatani M. Chroiric eosinophilic pneumoiua due to visceral larva migrans. Intern Med 2002 41(6) 478-82. 

This form of tissue helminthiasis is caused by the migration of the larvae of dog and cat ascarids, Toxocara canis and Toxocara cati in the visceral tissues of humans. The disease is more common in children than the adults who often come in contact with the eggs of T. canis or T.catti while playing on the ground polluted by cat and dog faeces. The infection by Toxocara in dogs is cosmopolitan however, surveys indicate that it is prevalent in the U.S.A., Britain, Africa and some parts of Asia [31,32]. In humans the rate or incidence of visceral larva migran is low nevertheless nearly 10,000 people are estimated to carry this disease around the world [24]. 

Visceral larva migrans Toxocara canis, T. cati Diethylcarbamazine, thiabendazole, mebendazole... 

Thiabendazole, an anthelmintic (22 mg/kg t.i.d. after meals), is indicated for the treatment of strongyloidiasis (threadworm infection), cutaneous larva migrans (creeping eruption), and visceral larva migrans. 

It is the anthelmintic drug of first choice in hookworm, pinworm, roundworm, whipworm, guinea worm, in filariasis, and also as an alternative drug for Visceral Larva Migrans. It is also employed as an adjunct to steroids for curing trichinosis. 

Toxocariasis (Ocular/visceral larva migrans) Toxocara canis... 

Visceral larva migrans The migration of larvae of Toxocara species in human tissues, where they cause damage and allergic reactions. 

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