Vinyl Fluoride, Inhibited

Vinyl Fluoride, Inhibited Fluosilicic Acid Fluosulfonic Acid Fluosulfonic Acid Calcium Fluoride Fluosilicic Acid Calcium Fluoride Fluosulfonic Acid... 

VINYL FLUORIDE, INHIBITED Fiuoroethylene, Monofiuoro-ethylene Flammable Compressed Gas 4 2... 

SYNS ETHENE, FLUORO- ETHYLENE, FLUORO-(8CI) FLUOROETHENE FLUOROETHYLENE MONOFLUOROETHYLENE VINYL FLUORIDE, inhibited pOT)... 

Vinyl fluoride (VF) [75-02-5] (fluoroethene) is a colorless gas at ambient conditions. Vinyl fluoride is flammable in air between the limits of 2.6 and 22 vol.%. Minimum ignition temperature for VF and air mixtures is 400°C. Adding a trace amount (<0.2%) of terpenes is effective to prevent spontaneous polymerization of vinyl fluoride. Inhibited vinyl fluoride has been classified as a flammable gas by the U.S. Department of Transportation. 

Vinyl Fluoride Inhibited Fluoroethylene Monofluoro Ethylene ... 

Vinyl Fluoride Inhibited Protective goggles, safety glasses, self-contained breathing apparatus. Remove victim to fresh air. If frostbite has occurred, flush areas with warm water and treat burn. ... 

Vinyl Fluoride, Inhibited Data not available Data not available Data not available Data not available... 

Vinyl Fluoride, Inhibited Not pertinent Not pertinent 2.6 21.7 Allow fire to burn out, stop the flow of gas if feasible. Cool adjacent containers with water Not pertinent Vapor is heavier than air and can travel to a source of ignition and flash back. Containers may explode 725 No ... 

Vinyl Fluoride, Inhibited Vinyl Fluoride, Zinc Bromide Zinc Bromide... 

Vinyl Fluoride, Inhibited — (i) Chemical Designations — Synonyms Fluoroethylene, Monofluoro ethylene Chemical Formula CH2 = CHF (ii) Observable... 

Vinyl Fluoride, inhibited 1860 17 Zinc Arsenate and Zinc Arsenile 1712 53... 

Carbonyl reagents, such as semicarbazide and phenelzine (27), are inactivators of SSAO. In a strategy that includes two inactivating structural motifs (allylamine and hydrazine), a series of allyl hydrazines including the series 28a-c as well as the fluoroallyl analogue 29 were prepared. Compounds 28a-c were potent irreversible inhibitors of SSAO, and compounds 28a,c had particularly good selectivity with respect to MAO inhibition. The presence of the vinyl fluoride in 29 had little effect on potency but did result in a loss in selectivity [82]. 

On the basis of a similar approach used with MDL 101731, irreversible inhibitors of SAH hydrolase have been designed.However, the supposed addition-elimination mechanism of a nucleophile of the enzyme onto the Michael acceptor has been ruled out the hydrolysis of the vinyl fluoride into aldehyde is responsible for the irreversible inhibition (Figure 7.59). ° ... 

Figure 7.62 Inhibition of the steroid Ci7(20)lyase by vinyl fluorides. ...

Vinylidene fluoride is taken up rapidly via the pulmonary route in rats, but at equilibrium the mean concentration (by volume) in rats was only 23% of that in the gaseous phase. Metabolism proceeded very slowly and was saturable at exposure concentrations of about 260 mg/m Its maximum rate was 1% that of vinyl chloride and less than 20% that of vinyl fluoride there has been a report of an increase in the urinary excretion of fluoride in exposed rats. No alkylating intermediate was demonstrated after passage through a mouse-liver microsomal system. However, vinylidene fluoride inhibits mixed-function oxidase activity in vitro and, like similar halogenated compounds that are transformed to reactive metabolites, it alters rat intermediary metabolism, leading to acetone exhalation (lARC, 1986). 

M. Frederickson, J. R. Coggin, and C. Abell, Vinyl fluoride as an isoelectronic replacement for an enolate anion Inhibition of type II dehydroquinases, Chem. Commun., (2002) 1886-1887. 

VINYL FLUORIDE or VINYL FLUORIDE MONOMER (75-02-S) Flammable gas. Able to polymerize unless inhibited (0.2% terpenes are recommended). Violent reaction with oxidizers. Heat of combustion forms toxic hydrogen fluoride gas. May accumulate static electrical charges, and may cause ignition of its vapors. 

While partially fluorinated alkenes such as vinyl fluoride and vinylidene fluoride polymerize with the same facility as tetrafluoroethylene, the latter is unique in the class of the perfluoroalkenes with the respect to the ease of polymerization as will be described later. Perfluoroalkenes such as hexafluoropropylene (HFP) and hexafluorobutadiene polymerize only with great difficulty as the result of the steric inhibition in the propagation step [598]. HFP can be converted to high-molar-mass polymer only at pressures above 1000 atm. The polymerizations are carried out most conveniently in a perfluorinated solvent using perfluorinated free-radical initiators [599]. For the polymerization of hexafluorobutadiene, similar conditions are reported [600]. Due to these very drastic polymerization conditions, these oligomers/polymers are not yet commercially applied. 

Commercial vinyl fluoride is usually inhibited by terpenes like d-limonene to prevent autopolymerization duiing transportation and handling. The inhibitor is removed by distillation just prior to polymerization. 

A process for continuous polymerization of VF in aqueous medium has been described in the litera-A mixture of vinyl fluoride, water, and a water-soluble catalyst was stirred at 50-250°C and 15-100 MPa. A small amount of a monoolefin (Cj—C3) was continuously introduced into the reactor to inhibit the bulk polymerization of vinyl fluoride to low molecular weight polymers. The water-soluble catalyst generated free radieals, which initiated the polymerization. Catalysts ineluded ammonium persulfate, organie peroxides, and water-soluble azo initiators. In a two-stage eontinuous polymerization, the polymer partieles formed in the first stage aeted as nucleation sites for the second reaction zone. l... 

Monomers that copolymerize with thiocarbonyl fluoride include olefins, vinyl halides, vinyl esters, ally esters, acrylates, vinyl ethers, and vinyltrichloro-silane. Nonconjugated diolefins lead to crosslinked products. Conjugated dienes inhibit polymerization. 

METHYL-l-PHENYL-ETHENE (98-83-9) Forms explosive mixture with air (flash point 129°F/54°C). Violent reaction with strong oxidizers, butyl lithium, oleum, xenon tetra-fluoride. Unless inhibited, forms unstable peroxides. Incompatible with acids. Reacts with heat and/or lack of appropriate inhibitor concentration, and/or contact with catalysts for vinyl or ionic polymerization, such as aluminum, iron chloride, or 2,5-dimethyl-2,5-di(rert-butylperoxy)hexane. The uninhibited monomer vapor may block vents and confined spaces by forming a solid polymer material. 

---