Vaginal jellies

Gum acacia and tragacanth are used in tablets, suppositories, vaginal jellies, and diabetic foods as excipients. A few cases of asthma have been reported to such vegetable gums (Gelfand 1943). Brown and Crepea (1947) reported a patient who was sensitive to tablets containing 0.005 mg tragacanth. 

Calcium chloride Potassium phosphate acidifier, urinary pharmaceuticals Potassium phosphate dibasic acidifier, vaginal jellies Ricinoleic acid acidity reducer, abdominal Magnesium silicate acidity regulator, food... 

Extensively used in vaginal jellies and creams, in emulsions (e.g., cod liver oil), low-calorie syrups and elixirs, and as binding agent or demulcent in tablets and lozenges. 

Phosphodiesterase 5 inhibitors such as sildenafil are effective for MS-induced erectile dysfunction.14 In women, vaginal dryness or dyspareunia may respond to lubricating jellies. 

A series of DCE-based formulations containing Igepal CO-630 Special (N9) and dextran sulfate (DS) were evaluated for in vitro contraceptive testing. Also included in the screening tests were placebos, N9, two commercial spermicidal products (Conceptrol and KY Plus), vaginal moisturizer products (KY Jelly and Replens ), and saline. Test results are summarized in Table 6. The N9-containing products exhibited similar spermicidal activity, as illustrated by the minimum effective concentration (MEC). Samples without N9 did not have spermicidal activity. DCE placebo vehicle inhibits sperm penetration into the cervical mucus, illustrated by the very low MOET values after 1 10 and 1 160 dilutions. This activity has not been reported for anionic or nonionic polymer vehicles. There are no striking differences... 

Drugs may also be administered locally in the form of bougies, jellies for urethra, pessaries, vaginal tablets, creams and douches for vagina and suppositories for rectal administration. 

Vaginal argyria has been attributed to a combination of silver sulfadiazine and Aci-Jel (a buffered acid jelly containing acetic acid) (19). 

Polyvinyl alcohol is a nonionic surfactant used as stabilizer, lubricant, or viscosity builder in ophthalmic preparations and as a Jelly builder for topical preparations. This product is FDA-approved for ophthalmic.s, orals, injectablcs. topicals, and vaginals. and is described in USP/NF and Martindale Extra Pharmacopoeia. 

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