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Ultrafiltration strategies

P. Zumbusch, W. Kulcke, G. Brunner. Use of alternating electric fields as antifouling strategy in ultrafiltration of biological suspensions. Introduction of a new experimental procedure for crossflow filtration. J Memb Sci 142-.15 (1998). R. L. Rowley, T. D. Shupe, M. W. Schuck. A direct method for determination of chemical potential with molecular dynamics simulations. 1. Pure components. Mol Phys 52 841, 1994. [Pg.797]

Figure 11.11 Overview of the procedure by which hCG may be purified from the urine of pregnant females at laboratory scale. Production-scale systems would be at least partially based upon such a purification strategy. Although initial concentration steps could involve precipitation, the use of ultrafiltration would now be more common... Figure 11.11 Overview of the procedure by which hCG may be purified from the urine of pregnant females at laboratory scale. Production-scale systems would be at least partially based upon such a purification strategy. Although initial concentration steps could involve precipitation, the use of ultrafiltration would now be more common...
Several strategies have been described for the preconcentration of sample components present at low concentrations. These techniques include zone sharpening,28-29 on-line packed columns,30 and transient capillary isotachophoresis (cITP).31-32 Other standard laboratory techniques are often used, including solid-phase extraction, protein precipitation, ultrafiltration, etc. Two important points to keep in mind when selecting a concentration protocol are the sample requirements of the method and the potential selectivity on relative concentrations of sample components. The latter point applies to purity and concentration analysis. [Pg.179]

One approach to delivering increased performance in a membrane process is to complement one separation mechanism with another. Vapor-arbitrated pervaporation is an example of this strategy. In bioseparations, as will be covered in a later section, a similar integration of several process enhancements in High-Performance Tangential How Filtration is responsible for dramatic improvement in separation efficiency of protein mixtures once considered unachievable by means of conventional ultrafiltration. [Pg.378]

Thormann et al. (1993) have published an overview of the strategies for using MEKC to monitor drugs in body fluids (serum, urine, saliva) they discuss buffer selection and sample preparation (direct injection, ultrafiltration, solid phase extraction. [Pg.171]

Zumbusch P and Kulcke W. Use of alternating electrical fields as anti fouling strategy in ultrafiltration of biological suspensions Introduction of new experimental procedure for crossflow filtration. J Membr Sci 1998 142 75-86. [Pg.1085]

The addition of mineral salts to alter protein and mineral equilibria in milk is a strategy that has been used to manipulate milk functionality, either alone or in combination with other processing treatments, such as alteration of pH, ultrafiltration, diafiltration, heating and cooling, or static high-pressure treatment. [Pg.13]

A range of membrane processes are used to separate fine particles and colloids, macromolecules such as proteins, low-molecular-weight organics, and dissolved salts. These processes include the pressure-driven liquid-phase processes, microfiltration (MF), ultrafiltration (UF), nanofiltration (NF), and reverse osmosis (RO), and the thermal processes, pervaporation (PV) and membrane distillation (MD), all of which operate with solvent (usually water) transmission. Processes that are solute transport are electrodialysis (ED) and dialysis (D), as well as applications of PV where the trace species is transmitted. In all of these applications, the conditions in the liquid boundary layer have a strong influence on membrane performance. For example, for the pressure-driven processes, the separation of solutes takes place at the membrane surface where the solvent passes through the membrane and the retained solutes cause the local concentration to increase. Membrane performance is usually compromised by concentration polarization and fouling. This section discusses the process limitations caused by the concentration polarization and the strategies available to limit their impact. [Pg.260]


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