Tumori genesis

Yang, E.V. and Glaser, R., Stress-induced immunomodulation Implications for tumori-genesis, Brain Behav. Immun., 17, 37, 2003. 

Zhang L, Ymg W, Mao Y et al. Loss of clusterin both in serum and tissue correlates with the tumori-genesis of esophageal squamous cell carcinoma via proteomics approaches. World J Gastroenterol 2003 9 650-654. 

Stevens, J.T., C.B. Breckenridge, L.T. Wetzel, J.H. Gillis, L.G. Luempert III, and J.C. Eldridge (1994). Hypothesis for mammary tumori-genesis in Sprague-Dawley rats exposed to certain triazine herbicides. J. Toxicol. Environ. Health, 43 139-154. 

The use of animal models for breast cancer allows control of single dietary variables. In such studies, diets high in fat have increased the incidence of spontaneous (19-22), chemically induced (23-26), and radiation-induced mammary tumors (27), and enhanced the growth of transplantable breast tumors (28-31). The effects of protein on breast cancer have not been studied as extensively, and the results have been less consistent. Several investigators have found no effect from increasing dietary protein (32,33), whereas others have noted a stimulation (34,35) or an inhibition of mammary tumori-genesis (36,37). 

Kim, D.J. et al., Chemoprevention by lycopene of mouse lung neoplasia after combined initiation treatment with DEN, MNU, and DMH, Cancer Lett, 120, 15, 1997. Risio, M. et al.. Apoptosis, cell replication, and Western-style diet-induced tumori-genesis in mouse colon. Cancer Res., 56, 4910, 1996. 

Donehower LA, Harvey M, Vogel H, et al. Effects of genetic background on tumori-genesis inp53-deficient mice. Molec Carcinogen. 1995,14 16-22. 

Sinicrope FA, Ruan SB, Cleary KR, et al, bcl-2 and p53 oncoprotein expression during colorectal tumori-genesis. Cancer Res 1995 55 237-41. 

Bachman, A. N., Curtin, G. M., Doolittle, D. J., and Goodman, J. 1. (2006). Altered methylation in gene-specific and GC-rich regions of DNA is progressive and nonrandom during promotion of skin tumori-genesis. Toxicol Sci 91(2), 406-418. 

Moore PS, Orlandini S, Zamboni G, et al. Pancreatic turnouts molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumori-genesis. Br J Cancer. 2001 84 253-262. 

Johnson, B.E., Gibbs, N.K., and Ferguson, J., Quinolone antibiotic with potential to photosensitize skin tumori-genesis, J. Photochem. Photobiol. B Biology, 37, 171-173, 1997. 

Joseph P, MuchnokTK, Klishis ML, Roberts JR, Antonini JM Whong WZ and Ong T (2001) Cadmium-induced cdl transformation and tumori-genesis are associated with transcriptional activation of c-fos, c-jun, and c-myc proto-oncogenes role of cellular calcium and reactive oxygen species. Toxicol Sd 61 295-303. 

Hydroxylation of estradiol by human uterine myometrium and myoma microsomes Implications for the mechanism of uterine tumori-genesis. Proc. Natl. Acad. Sci. USA 92,9220-9224. 

Taketo, M.M. (1998) Cyclooxygenase-2 Inhibitors in Tumori-genesis (Part I), J. Natl. Cancer Inst. 90,1529-1536. 

Fig. 2. The role of CXC chemokines in regulating angiogenesis in the context of tumori-genesis. The over- and underexpression of the angiogenic (ELR+ CXC chemokines) and angiostatic (ELR CXC chemokines), respectively, lead to tumor progression via the promotion of tumor-associated neovascularization. In contrast, attenuation of the angiogenic or reconstitution of the angiostatic CXC chemokines leads to tumor regression via the inhibition of tumor-associated neovascularization.

T (1997) Bronchial hyperreactivity, increased endotoxin lethahty andmelanocytic tumori-genesis in transgenic mice overexpressing platelet-activating factor receptor. EMBO /, 16, 133-142. 

---