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Tumor cell metastasis

The physiological function of heparin is not completely understood. It is found only in trace amounts in normal circulating blood. It exerts an antihpemic effect by releasing lipoprotein lipase from endothehal cells heparinlike proteoglycans produced by endothelial cells have anticoagulant activity. Heparin decreases platelet and inflammatory cell adhesiveness to endothelial cells, reduces the release of platelet-derived growth factor, inhibits tumor cell metastasis, and exerts an antiproliferative effect on several types of smooth muscle. [Pg.259]

Honn, K. V., Busse, W. D. and Sloane, B. F. (1983). Prostacyclins and thromboxanes implications for their role in tumor cell metastasis. Biochem. Pharmacol. 32,1-11. [Pg.300]

Vlodavsky, I., Fuks, Z. and Schirrmacher, V. (1983). In vitro studies on tumor cell interaction with the vascular endothelium and the subendothelial basal lamina relationship to tumor cell metastasis. In The Endothelial Cell-a Pluripotent Control Cell of the Vessel Wall (Thilo-Koemer, D. G. S. and Freshney, R. 1., eds.). Karger, Basel, pp. 126-157. [Pg.341]

Carbohydrates specifically mediate numerous biological processes that include cell adhesion and differentiation, pathogen invasion, tumor cell metastasis, and inflammatory responses and are therefore of great interest for the generation of therapeutics (/-i). Unfortunately, the molecular basis for most of... [Pg.272]

Honn KV. Inhibition of tumor cell metastasis by modulation of the vascular prostacyclin/ thromboxane A2 system. Clin Exp Metastasis. 1 (1983) 103-114. [Pg.163]

Honn KV, Tang DG, Gross IM, Renaud C, Duniec ZM, Johnson CR, Diglio CA. Enhanced endothelial cell retraction mediated by 12(S)-HETE a proposed mechanism for the role of platelets in tumor cell metastasis. Exp Cell Res. 210 (1994b) 1-9. [Pg.163]

Swainsonine may also prove to be an effective chemotherapeutic agent against certain types of cancers. Thus, swainsonine has been found to reduce tumor cell metastasis, enhance cellular immune responses and resuce solid tumor growth in... [Pg.1636]

Nitric Oxide Inhibits TUmor Cell Metastasis via Dysregulation of the NF-icB/Snail/RKIP Loop... [Pg.209]

Nitric Oxide Inhibits Tumor Cell Metastasis... [Pg.211]


See other pages where Tumor cell metastasis is mentioned: [Pg.175]    [Pg.7]    [Pg.294]    [Pg.1810]    [Pg.2657]    [Pg.85]    [Pg.140]    [Pg.30]    [Pg.34]    [Pg.71]    [Pg.101]    [Pg.635]    [Pg.985]    [Pg.161]    [Pg.8]    [Pg.315]    [Pg.736]    [Pg.277]    [Pg.9]    [Pg.1809]    [Pg.2028]    [Pg.224]   
See also in sourсe #XX -- [ Pg.7 , Pg.8 ]




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Metastasis

Tumor cells

Tumor metastases

Tumoral cells

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