Troubleshooting suggestions

No signal Don t panic — this happens to everyone. Do you see any noise on the output of the receiver Turn 

Perhaps the transmitter is not putting out pulses. Can you see pulse feedthrough on the start of the scope trace Can you use the scope to check the output of the transmitter to make sure that it is pulsing (Use an indirect method. See Section VI.A.l.) 

If you have checked everything indicated above, you must have another major problem Do you have the right 

If there is a signal but it is very weak, there are several possible causes. 1) The transmitter pulse length might be off. 2) The pulse repetition rate might be too fast for the 

What follows is a list of useful equipment for maintenance, troubleshooting, and modest instrument modification. 

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Troubleshooting is described by suggesting possible causes of the more common problems and discussing corrective measures. 

Troubleshooter" boxes, which help identify potential bottlenecks and suggest ways to overcome them. 

This chapter highlights the common problems, symptoms, and probable causes that may be encountered in troubleshooting FCC units. In addition, a systematic approach is outlined to provide solutions and corrective action. The suggested solutions are necessarily generic but apply to a wide variety of units. 

The book is divided into four parts. Part I, The Fundamentals of GC/MS, includes practical discussions on GC/MS, interpretation of mass spectra, and quantitative GC/MS. Part II, GC Conditions, Derivatization, and Mass Spectral Interpretation of Specific Compound Types, contains chapters for a variety of compounds, such as acids, amines, and common contaminants. Also included are GC conditions, methods for derivatization, and discussions of mass spectral interpretation with examples. Part III, Ions for Determining Unknown Structures, is a correlation of observed masses and neutral losses with suggested structures as an aid to mass spectral interpretation. Part IV, Appendices, contains procedures for derivatization, tips on GC operation, troubleshooting for GC and MS, and other information which are useful to the GC/MS user. Parts I to III also contain references that either provide additional information on a subject or provide information about subjects not covered in this book. 

Problems that arise with HPLC experiments are usually associated with abnormally high or low pressures, system leaks, worn injectors parts, air bubbles, or blocked in-line filters. Sometimes these manifest themselves on the chromatogram and sometimes they do not. In the following subsections, we address some of the most common problems encountered, pinpoint possible causes, and suggest methods of solving the problems. You can also refer to the troubleshooting guide in Chapter 12 for possible solutions. 

NOTE See Troubleshooting section for suggestions concerning optimization of the protocol, particularly when employing AP-based systems. 

Suggested changes are to increase the percentage A at the beginning if the retention time for early peaks are considerably longer than that shown in Figure FI.3.2 or decrease it at 20 min if the later peaks are not well resolved (see Critical Parameters and Troubleshooting). 

This section is designed to assist in troubleshooting system problems. It is not a systematic approach as described in Chapter 10, which always yields better results. Keeping this in mind, I have listed a series of commonly seen problems, possible causes, and suggested treatments. 

The no is the exact opposite of the yes. Such people shoot down every suggestion you have with a lot of negative reasons. Make these people useful by having them troubleshoot your ideas. They may find a potential problem where you have not. When dealing with such people, bring up negative reasons and find a way armmd them before they do. 

Dolan (refer to Suggested Additional Reading ) has very effectually set forth five rules of thumb for HPLC troubleshooting. 

Kister says that d/b plots are primarily used when there is a tight spec, on a nonkey component or a concern about the distribution of an intermediate key component. His book shows d/b curves for various feed stage locations on a plot of the mole ratio of a reference component in the distillate to the bottom product, versus the relative volatility of each component to this reference component. This plot is made on log-log paper. The optimum feed produced a curve closest to linear. The d/b plot is suggested as a troubleshooting tool in the subsection of the Troubleshooting section, Fractionation Operating Problems. ... 

Design a piece of equipment Propose and design new equipment or a new process Evaluate a current piece of equipment or a process Suggest changes for equipment or a process Debottleneck by increasing the limiting capacity in a process Troubleshoot to correct faulty operation... 

Troubleshoot the reaction system to deduce the problems for an exothermic and an endothennic reaction. Next, suggest measures to correct the problem. You can change, and along with T, and Ty... 

Rotomolding and transfer molding are also affected by a number of variables that are difficult to control and hard to scale when the size and design of the part changes. It is important to follow a set of troubleshooting guidelines to take corrective action when the part is defective. Tables 10.15 and 10.16 provide lists of problems and suggested corrective actions. 

The above statements must not be interpreted to suggest that operation personnel and troubleshooters need not be familiar with the primary design. Quite the contrary. A good troubleshooter must have a solid understanding of primary design because it provides the foundation of our distillation know-how. However, the above statements do suggest that in general, when a troubleshooter examines the primary... 

Table 14.3 provides a checklist for troubleshooting nonclosure of material and energy balances. Reference 2 contains several useful suggestions for carrjdng out material and energy balances on plant columns. 

The microarray may need to be scanned several times before the ideal laser power and PMT settings are ascertained. If your scanner has the option of running an Automatic Sensitivity Calibration, this option may be perused. We recommend that you also refer to our published reverse capture troubleshooting tips for additional suggestions (9). 

In most troubleshooting situations, time is not of the essence management and the operators have time to consider what is the best action to take. A troubleshooting scenario suggests problems such as the following ... 

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