Toxicological and pharmacological

Non-Clinical Study Reports Toxicological and Pharmacological Tests 111... 

Dubois M, Pfohl-Leszkowicz A, De Waziers I, etal. 1996. Selective induction of the cyp3a family by endosulfan and DNA-adduct formation in different hepatic and hepatoma cells. Environmental Toxicology and Pharmacology l(4) 249-256. 

Fensterheim, R.J. (1993). Documenting temporal trends of polychlorinated-biphenyls in the environment. Regulatory Toxicology and Pharmacology 18, 181-201. 

Uguz, C., Togan, I., Eroglu, Y., Tabak, L, Zengin, M., and Iscan, M. (2003). AUcylphenol concentrations in two rivers of Turkey. Environmental Toxicology and Pharmacology 14, 87-88. 

Watanuki, H., Yamaguchi, T., and Sakai, M. (2002). Suppression in function of phagocytic cells in common carp Cyprinus carpio L. injected with estradiol, progesterone or 11-ketotestosterone. Comparative Biochemistry and Physiology C—Toxicology and Pharmacology 132, 407 13. 

Overton E. Osmotic properties of cells in the bearing on toxicology and pharmacology. Z Physik Chem 1897 22 189-209. 

Landry, T.D., Chew, L., Davis, J.W. et al. (2003) Safety evaluation of an alpha-amylase enzyme preparation derived from the archaeal order Thermococcales as expressed in Pseudomonas fluorescens biovar I. Regulatory Toxicology and Pharmacology, 37 (1), 149-168. 

Ingle, L. 1965. A Monograph on Chlordane. Toxicological and Pharmacological Properties. Library of Congress Number 65-28686. 88 pp. 

The toxic effects model relies on many consensus parameters that describe toxicological and pharmacological effects. These consensus parameters are the result of an in-house review of available toxicological data. Other parameters (e.g. those derived from NATO study groups) may, however, be used when necessary or desired. 

A Systematic Approach for Evaluating the Quality of Experimental Toxicological and Ecotoxicological Data, Regulatory Toxicology and Pharmacology, 1997, 25, 1. 

European Union. The standard European Union toxicology and pharmacologic data requirements for a pharmaceutical include... 

Generally, in vivo nonclinical studies should be designed to include a sufficient number of animals per group to permit a valid estimation of a drug s toxicologic and pharmacologic effects in terms of incidence, severity and the dose-response relationships involved (Thomas and Myers, 1998). The latter point requires, as... 

Available biological, toxicological, and pharmacological information on the test material and related materials (which involves a thorough search of the scientific literature). 

Bames DG, Dourson M. 1988. Reference dose (RfD) Description and use in health risk assessments. Regulatory Toxicology and Pharmacology 8 471-486. 

P. Eyer, in Biological Oxidation of Nitrogen in Organic Molecules Chemistry, Toxicology and Pharmacology (Eds. J. W. Gorrod and L. A. Damani), Horwood, Chichester, 1985, p. 386. 

F. Muhammad and J. E. Riviere. In vivo models. In J. E. Riviere (ed.), Dermal Absorption in Toxicology and Pharmacology, CRC Press, Taylor Francis Group, Raleigh, North Carolina, 2006, pp. 49-70. 

Sambruy Y, Ferruzza S, Ranaldi G, De Angelis I (2001) Intestinal cell culture models. Applications in toxicology and pharmacology. Cell Biol Toxicol 17 301— 317. 

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