Toxic Weapons Convention

Highly toxic perfluoroisobutylene (PFIB) poses a serious health hazard to the human respiratory tract. PFIB is a thermal decomposition of polytetrafluo-roethylene (PTFE), e.g., Teflon. PFIB is approximately lOx as toxic as phosgene. Inhalation of this gas can cause pulmonary edema, which can lead to death. PFIB is included in Schedule 2 of the Chemical Weapons Convention (CWC), the aim of the inclusion of chemicals such as PFIB was to cover those chemicals, which would pose a high risk to the CWC. 

This class of agents is not covered by the Chemical Weapons Convention. Because of the toxicity of the agents and lack of commercial application, carbamate nerve agents would be prohibited based on the Guidelines for Schedules of Chemicals. 

In 1972, more than 100 countries including the U.S. signed the Convention on the Prohibition of the Development, Production, and Stockpiling of Biologic and Toxic Weapons and Their Destruction — a measure designed to limit further development or use of biological and chemical weapons. Unfortunately, the accord has been breached several times. 

There are essentially millions of chemical compounds known to humanity, but only a limited number are weaponized by conventional militaries. The Organization for the Prohibition of Chemical Weapons (OPCW), the 184-member watchdog agency enforcing the guidelines of the Chemical Weapons Convention (CWC), has identified 55 chemical agents and their precursors that can be used as weapons (OPCW, 2005). Although some of the chemicals are well known (e.g. sarin, soman, VX, mustard), other less obvious choices for chemical terrorism include industrial chemicals such as chlorine and toxic precursors, which are considered weapons of opportunity . 

U.S. Department of Defense A = Army Toxicity Summary Chemical C = Chemical Weapons Convention Schedule 3.A Toxic Chemical... 

Black RM, Noort D. Methods for the retrospective detection of exposure to toxic scheduled chemicals. Part A analysis of free metabohtes. In Mesilaakso M, ed. Chemical Weapons Convention Chemicals Analysis Sample Collection, Preparation, and Analytical Methods. Chichester, West Sussex, England John Wiley Sons 2(K)5 4()3 431. 

The majority of substances listed on Schedule 1 of the Chemical Weapons Convention are considered to be percutaneous hazards (OPCW, 1993). In particular, sulphur mustard (HD) and VX are the most extensively studied agents of this genre and are representative of chemical warfare agents that exhibit mainly local or systemic percutaneous toxicity, respectively (Table 1). 

As already noted, a central provision of the Chemical Weapons Convention (CWC) is the general purpose criterion which prohibits Toxic chemicals and their precursors, except where intended for purposes not prohibited under this Convention, as long as types and quantities are consistent with such purposes . The implementation of this general purpose criterion is placed by Article VI on each State Party which shall adopt the necessary measures to ensure that toxic chemicals and their precursors are only developed, produced, otherwise acquired, retained, transferred, or used within its territory or in any other place under its jurisdiction or control for purposes not prohibited under this Convention . 

Chemical weapons are totally prohibited under the provisions of the Chemical Weapons Convention. The General Purpose Criterion ensures that all toxic chemicals, past, present and future, are prohibited unless they are for purposes not prohibited under the Convention. The regime against chemical weapons will become more effective as the Chemical Weapons Convention approaches universality and international initiatives in regard to toxic chemicals become more widely applied throughout the world. National measures to ensure that toxic chemicals do not present a risk to health and safety can and should be harnessed to ensure effective implementation of the obligations under the Chemical Weapons Convention to ensure that such chemicals are only used for purposes permitted under the Convention. 

The term chemical warfare agents ideally would comprise all toxic chemicals that have been developed, produced, or used in a military context with the intention of utilizing its toxicity to man, animals or plants as its primary weapons characteristic. This definition excludes a considerable number of toxic chemicals used in a military environment, which serve other purposes a case in point is rocket fuel, which is highly toxic, but whose primary purpose is the propulsion of a missile. On the other hand, this definition goes beyond that used in the Chemical Weapons Convention (CWC) according to the CWC s Article II, para. 2 only those chemicals which through its chemical action on life processes can cause death, temporary incapacitation or permanent harm to humans or animals (emphasis added)1 count as chemical warfare agents. 

In order to define which acts are permitted and which are prohibited under the Chemical Weapons Convention, a definition of what constitutes a chemical weapon is required. Besides, the drafters of the CWC had to address the question of which toxic chemicals to cover in the new international treaty. 

Fig. 30-1. Toxicity, in mouse LD50 (see Table 30-2), plotted against the quantity of toxin required to provide a theoretically effective open-air aerosol exposure, under ideal meteorological conditions, to an area of 100 km2. Although the toxicity is based on direct studies with mice, it is believed to be very similar in humans. The mathematical model corrects for human parameters such as respiration. Ricin, saxitoxin, and botulinum, and trichothecene mycotoxins (T-2) kill at the concentrations depicted. Adapted from Spertzel RO, Wannemacher RW, Patrick WC, Linden CD, Franz DR. Technical Ramifications of Inclusion of Toxins in the Chemical Weapons Convention (CWC). Alexandria, Va Defense Nuclear Agency 1992 18. DNA Technical Report 92-116.

Chemical Weapon Convention (CWC) Schedules, In the CWC, the three categories into which toxic chemicals and their precursors are divided based on the threat the chemicals/precursors pose to the purpose and objectives of the treaty and the extent of their commercial use. 

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