Toxic substances classifying

Substances classified as toxic (T R23/24/25) for acute toxicity Substances classified as harmful (Xn R48/20/21/22) for repeated dose toxicity Substances classified as carcinogens, mutagens, and reproductive toxins in Category 3 Substances classified as skin sensitizers (Xi R43)... 

Health nd Safety Factors. The mononitrochlorobenzenes are toxic substances which may be absorbed through the skin and lungs giving rise to methemoglobin. Their toxicity is about the same as or greater than that of nitrobenzene. The para isomer is less toxic than the ortho isomer, and the maximum allowable concentration that has been adopted for -nitrochlorobenzene is 1 mg/m (0.1 ppm) (6). The mononitrochlorobenzenes are moderate fire hazards when exposed to heat or flame. They ate classified by the ICC as Class-B poisons. The same handling precautions should be used for these compounds as are used for nitrobenzene. 

Unlike chloroformates, diethyl and dimethyl carbonates are only mildly irritating to the eyes, skin, and mucous membranes. Diethylene glycol bis(aHyl carbonate) may be irritating to the skin, but it is not classified as a toxic substance however, it is extremely irritating to the eyes. 

Cover the control of substances classified as very toxic, toxic, harmful, coiTosive, sensitizing or imtant under the Chemicals (Hazard Information and Packaging for Supply) Regulations 1994 (as amended) and to substances which have MELs or OESs. Also other substances that have chronic or delayed effects and biological agents. Special provisions are included for carcinogens. 

In de-aerated conditions, for instance in most central heating systems, little if any attack on copper occurs . As far as drinking waters are concerned, copper is not classified as a toxic substance or hazardous to health. To avoid any difficulties due to unpalatability, the maximum continuous copper content should not exceed 10 p.p.m., with a limit of 3 p.p.m. in water after standing overnight in copper pipes. A review of the subject by Grunau makes reference to 394 published papers. 

It was further concluded that the Toxic Substances Control Act is a new way of looking at environmental problems, a systematic and comprehensive approach, not limited to pollutants classified by their occurrence, as in air or water. TSCA contemplates the flow of potentially toxic substances from their origin, through use, to disposal. 

The Department of Defense memo may still have been too highly classified, leading to inadvertent violation of its rales. One example of a violation was the Top Hat program in which volunteers tested decontamination methods for various toxic substances. The authors observe that those operating under this protocol may have thought this study was not subject to the above policies. 

Toxic substances come in a variety of forms from a number of different sources. Those that come from natural sources are commonly called toxins, whereas those produced by human activities are called toxicants. They may be classified according to several criteria, including the following ... 

SeMet is classified as a very toxic substance. It should be stored in closed containers below 4°C in the freezer. SeMet should only be handled in a well-ventilated hood with rubber gloves, protective goggles and facial mask. To reduce the risk of accidental poisoning in the food and feed industry, pre-... 

The intention of the authorities, with the restriction of chemical leaking paints was to reduce the release of toxic substances to the sensitive productive coastal areas (Kemi 1998a). The Baltic Sea is considered an environmentally sensitive area, which later was acknowledged internationally by the International Maritime Organisation (IMO 2005) and classified as a Particularly Sensitive Sea Area (PSS A) in 2004 (IMO 2005). This was based on its unique environment, with low salinity and low biodiversity. Also, the Baltic Sea is in an evolutionary perspective a young sea and the organisms live in a very stressful environment, as they have not had time to fully adapt to the brackish water conditions (Kautsky and Tedengren 1992 Ryden et al. 2003). 

Management Based on Intrinsic Properties The complex life cycles of many substances prevent proper estimations of exposure. Therefore, precautionary policies primarily focus on intrinsic hazardous properties, i.e. assume that critical exposure is the case. Since hazardousness (e.g. chronic toxicity) is difficult to estimate, also substances classified as persistent and liable to bioaccumulate should be treated as hazardous and as action targets. 

Some competent authorities (CA) may require SDS s to be compiled for mixtures which are not classified for acute toxicity or aquatic toxicity as a result of application of the additivity formula, but which contain acutely toxic substances or substances toxic to the aquatic environment in concentrations equal to or greater than 1 % ... 

The criteria for substances classify acute toxicity by use of lethal dose data (tested or... 

NOTE 1 If a Category 1 reproductive toxicant or substance classified in the additional category for effects on or via lactation is present in the mixture as an ingredient at a concentration between 0.1% and 0.3%, every regulatory authority would require information on the SDS for a product. However, a label warning would be optional. Some authorities will choose to label when the ingredient is present in the mixture between 0.1% and 0.3%, whereas others would normally not require a label in this case. 

NOTE 2 If a Category 1 reproductive toxicant or substance classified in the additional category for effects on or via lactation is present in the mixture as an ingredient at a concentration of >0.3%, both an SDS and a label would generally be expected. 

NOTE For these categories the specific target organ/system that has been primarily affected by the classified substance may be identified, or the substance may be identified as a general systemic toxicant. Attempts should be made to determine the primary target organ of toxicity and classify for that purpose, e.g. hepatoxicants, neurotoxicants. One should carefully evaluate the data and, where possible, not include secondary effects, e.g. a hepatotoxicant can produce secondary effects in the nervous or gastro-intestinal systems. ... 

If bridging principles do not apply, classify under Aspiration hazard Category 2 Mixtures containing 10% or more of a substance or substances classified in Category 2 and having a kinematic viscosity of 14 mmVs or less, measured at 40 °C Mixtures which separate into two or more distinct layers, one of which contains 10% or more of a substance or substances classified in Category 2 aspiration toxicity hazard and has a kinematic viscosity of 14 mmVs or less, measured at 40 °C. Hazard statement May be harmful if swallowed and enters airways... 

Hundreds of chemicals are regulated under CERCLA they are classified as (i) hazardous substances and (ii) pollutants or contaminants. The definition of a hazardous substance under CERCLA is broad and is based on other environmental regulations. A CERCLA hazardous substance does not need to be a waste or waste material. It can be a commercial chemical, formulation, or product. A CERCLA hazardous substance is defined as any chemical regulated under the Clean Water Act, the Clean Air Act, the Toxic Substances Control Act (TSCA), or the Resource Conservation and Recovery Act (RCRA). However, two materials that are excluded from the hazardous substances list are petroleum and natural gas. A CERCLA pollutant or contaminant is defined as any other chemical or substance that will or may reasonably be anticipated to cause harmful effects to human or... 

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