Tert-butyl ketone

In radical reactions not involving bromine or chlorine on the substrate, rearrangements are much rarer One example is the fluorination of di-tert butyl ketone which produces perfluormated / rt-buty isobutyl ketone [J5] Although isolated yields are poor only the rearranged ketone could be isolated This is perhaps only the second example of a 1,2-acyl shift Low fluorine substrate ratios show that this rearrangement occurs after monofluorination... 

Pinacol upon dehydration with acid catalysts (e.., by distillation from 6N sulphuric acid or upon refluxing for 3-4 hours with 60 per cent, phosphoric acid or hydrated oxalic acid) is transformed into methyl tert.-butyl ketone or plnacolone ... 

Methylbutyl iso valerate, ml 77 Methyl tert-butyl ketone, h70 Methyl caprate, m226 Methyl caproate, m270 Methyl caprylate, m349 Methyl carbazate, m275... 

I) Acetaldehyde, Acetone, Di-tert-butyl ketone. Methyl tert-butyl ketone (reactivity towards HCN)... 

In 1998, a new type of light-sensitive linker based on the photolysis of tert-butyl ketones was developed by Peukert and Giese (Entry 7, Table 3.6). The proposed... 

Z)-2-Methyl-2-butenedioic acid, c270 Methyl 2-buten-l-oate, ml 92 3-Methylbutyl acetate, i80 2-Methylbutylamine, a251 Methyl tert-butyl ether, b460 Methyl tert-butyl ketone, h72... 

Interestingly, reduction of tert-butyl ketone 13 under the same conditions gave 1,3-diol 14 as a 1 1 mixture of diastereoisomers. Keck argued that samarium and its associated ligands are similar in size to the tert-butyl group and there is no preference for one organosamarium configuration over the other (Scheme 4.8).13... 

Two simple a, P-unsaturated acylsilanes, l-trimethylsilyl-2-propen-l-one (III) and l-trimethylsilyl-2-methyl-2-propen-l-one (IV) were chosen for polymerization studies. The polymerization of the carbon analogues of these a,p-unsaturated acylsilanes, that is, 4,4-dimethyl-2-propen-3-one (vinyl tert-butyl ketone, V) and 2,4,4-trimethyl-2-propen-3-one (isopropenyl tert-hutyl ketone, VI) has been studied by Willson et al. 16, IT), These authors reported that whereas V readily polymerizes under free-radical-polymerization conditions, VI undergoes polymerization only under anionic-initiation conditions in the presence of a crown ether as a complexing reagent. On the basis of UV and NMR spectroscopic data, Willson et al. (i6, 17) ascribed the difference in polymerization behavior to the nonplanar, unconjugated structure of ketone VI brought about by steric hindrance caused by the methyl group at C-2. 

C9H18 1,cls-2-dimethyl-trans-3-ethylcyclopentane. .. 15.750 161.023 1,2 18000 C9H180 di-tert-butyl ketone 815-24-7 14.683 173.786 1.2... 

Heating 2,3-dimethyl-2,3-diol, pinacol (24), at 80°C in the presence of Nafion-H gave a 92% yield of pinacolone (methyl-tert-butyl ketone) (25) (Eqn. 22.18). Similar yields were obtained with other ditertiary vicinal diols. Reaction of pinacol with either La-HY or H-ZSM-5 or aluminum exchanged montmorillonite 2 gave both pinacolone (25) and 2,3-dimethylbutadiene (26), resulting from the dehydration of the diol, in nearly equal quantities. Only a small amount of dehydration was observed when the rearrangement was run over... 

The Norrish type I reaction of acyclic and cyclic ketones in solution typically results in recombination, decarbonylation and disproportionation (hydrogen abstraction) products.903 For example, irradiation of di-tert-butyl ketone (265) in hexane solution provides nearly exclusively decarbonylation products from both the singlet and triplet states (>90% chemical yield), whereas the carbonyl group-containing products are produced only in traces (Scheme 6.111).922 923... 

KH 50% n-Octone/50% m-Xylene lot a-Methylstyrene KH Methyl tert-Butyl Ketone tot p-Cymene loi Tetrohydrofuron o I Diisobutyl Ketone l—o I Ethylbenzene KH 60% n-Octone/20% m-Xylene I- o l Methyl Isobutyl Ketone 30h KH Toluene... 

I - o — l Methyl tert-Butyl Ketone —o—l Mineral Spirits (53.1 % or.)... 

Triethylamine Diethylomine Methyl tert-Butyl Ketone n-Octane Phenyl Acetate Benzene... 

A sequential solid-phase peptide synthesis has been developed which makes use of both a photolabile linker and a photolabile protecting group (Scheme 8). The system is based on a tert-butyl ketone-derived linker, which is sensitive to... 

Table V. Apparent Quantum Yields for tert-Butyl Hydroperoxide Photolysis in the Presence of Methyl tert-Butyl Ketone 0.31M Hydroperoxide in Hexane at 36°C, A — 322 nm...

Butanone, 1-chloro-3,3-dimethyl- tert-Butyl chloro-methyl ketone 1-Chloro-3,3-dimethyl-2-butanone 1-Chloro-3,3-dimethylbutan-2-one Chloromethyl tert-butyl ketone a-Chloropinacolin a-Chloroplnacoline 1-Chloropinacolone Chlorpinakolin EINECS 236-920-6 1-Monochloropinacollne. 

Beiistein Handbook Reference) BRN 1752918 2-Butanone, 1,1-dichloro-3,3-dimethyi- 1,1-Dichlono-3,3-dimelhyl-2-butanone 1,1-Dichloro-3,3-dimethylbutan-2-one Dichloromethyl tert-butyl ketone Dichloropinacolin Dichloropinakolin ra.m-Dichlorpinakolin EINECS 245-111-7. 

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