Temperature shelf-life

Fully Processed Foods. Fully processed foods are processed and packaged so that the ambient temperature shelf life can exceed three to six... 

Diltiazem undergoes hydrolysis to desacetyl diltiazem in aqueous buffer solutions (pH 1-7) (35). Diltiazem is most stable at pH 5. The decomposition follows pseudo-first order kinetics. The extrapolated room temperature shelf-life was 42 days or 15.8 days at pH 5 or 2, respectively. Exposure of aqueous buffered solutions of diltiazem at pH 2 or 7 to UV radiation caused more degradation as compared to the same solutions protected from light, demonstrating the light sensivity of the compound in solution (34). The stability of diltiazem hydrochloride in aqueous sugar solutions (fructose, dextrose, sucrose, sorbitol and mannitol) was determined to be superior to that in pH 5 aqueous buffer (36). 

Calculations using Arrhenius plots, such as those described above, are carried out in the pharmaceutical industry every day. It should be made clear, however, that they involve a number of assumptions. It is assumed that the linearity of the graph obtained from equation (9.9) extends to room temperature, or, mathematically, that A and E are independent of temperature. If the line cannot be extrapolated to room temperature, shelf-life predictions are invalid. Second, it is assumed that the same chemical reaction is occurring with decomposition at high temperature as at low temperature. This is usually the case, but until proven it remains an assumption in most calculations. 

Leuprolide, used for the palliative treatment of prostate cancer, was formulated at 370 mg/ml in DMSO within an osmotically-driven implantable pump lasting 1 year, where the choice of DMSO provided 2 year room temperature shelf life, plus 1 year of implant life at 37°C (Stevenson et al., 1999 Wright et al., 2001). 

The thermal initiator is benzopinacol (4), which is stable at room temperature (shelf-life of the uncured liquid conformal coating is more than 6 months at room temperature), but which undergoes a homolytic cleavage upon heating to form diphenylhydroxy-methyl radicals (Equation 2), which are believed to initiate polymerization by hydrogen atom transfer to the double bond of the acrylate (Equation 3) (9). 

Storage configurations, maximum quantities, and minimum/maximum storage temperatures Shelf life considerations What to do in the event of a leak or spill What to do if an unwanted reaction starts How to fight a fire involving the material... 

Increase or room temperature shelf life to 18 months. 

There are important figures of merit (5) that describe the performance of a photodetector. These are responsivity, noise, noise equivalent power, detectivity, and response time (2,6). However, there are several related parameters of measurement, eg, temperature of operation, bias power, spectral response, background photon flux, noise spectra, impedance, and linearity. Operational concerns include detector-element size, uniformity of response, array density, reflabiUty, cooling time, radiation tolerance, vibration and shock resistance, shelf life, availabiUty of arrays, and cost. 

Stabilizers. Hydroquinone [123-31 -9] (4) is widely used in commercial resins to provide stabiHty during the dissolution of the hot polyester resin in styrene during the manufacturing process. Aeration of the styrene with oxygen (air) is required to activate the stabilizer, which is converted to an equiHbrium mixture of quinone and the quinhydrone (5) (11). At levels of 150 ppm, a shelf life of over 6 months can be expected at ambient temperatures. 

Li-CF X Li + CF X LIF + C 2.7 0.5 300 high voltage, long shelf life, wide operating temperature Rayovac Eagle Picher... 

Self-Discharge Processes. The shelf life of the lead—acid battery is limited by self-discharge reactions, first reported in 1882 (46), which proceed slowly at room temperature. High temperatures reduce shelf life significantly. The reactions which can occur are well defined (47) and self-discharge rates in lead—acid batteries having immobilized electrolyte (48) and limited acid volumes (49) have been measured. 

The molecular weight of the polymers is controlled by temperature (for the homopolymer), or by the addition of organic acid anhydrides and acid hahdes (37). Although most of the product is made in the first reactor, the background monomer continues to react in a second reactor which is placed in series with the first. When the reaction is complete, a hindered phenoHc or metal antioxidant is added to improve shelf life and processibiUty. The catalyst is deactivated during steam coagulation, which also removes solvent and unreacted monomer. The cmmbs of water-swoUen product are dried and pressed into bale form. This is the only form in which the mbber is commercially available. The mbber may be converted into a latex form, but this has not found commercial appHcation (38). 

What is the safe storage temperature for shelf life Kinetic data Data from 1 and 2 Isothermal Storage Test... 

The development of the mechanical seal advanced in parallel with elastomer technology. Mechanical seals using o-rings and other elastomer forms, benefited with improved shelf-life, maximum and minimum temperature limits, better chemical resistance, and higher pressure ratings. 

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