Telling the Story

Whereas Chapters 2 and 3 illustrate essential points with short examples. Chapter 4 tells the stories of four chemical products in more detail. These longer-form case studies integrate the technical and regulatory foundations of product stewardship and allow us to explore past risk-management decisions. Case studies of three chlorinated hydrocarbons show the effect of molecular structure on the behavior of a chemical in the environment and on the possible consequences of exposure. These case studies also show how 

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The chemistry of carboxylic acids is the central theme of this chapter The impor tance of carboxylic acids is magnified when we realize that they are the parent com pounds of a large group of derivatives that includes acyl chlorides acid anhydrides esters and amides Those classes of compounds will be discussed m Chapter 20 Together this chapter and the next tell the story of some of the most fundamental struc tural types and functional group transformations m organic and biological chemistry... 

Stanley G. Thompson joined my group on October 1, 1942 and it fell to his lot to discover the process that was chosen for use at Clinton Laboratories (in Tennessee) and the Hanford Engineer Works (in the state of Washington) for the separation of plutonium from uranium and the immense intensity of radioactive fission products with which it was produced in the nuclear chain reactors. Again I turn to my journal to tell the story ... 

The new delightful book by Greenstein and Zajonc(9) contains several examples where the outcome of experiments was not what physicists expected. Careful analysis of the Schrddinger equation revealed what the intuitive argument had overlooked and showed that QM is correct. In Chapter 2, Photons , they tell the story that Einstein got the Nobel Prize in 1922 for the explaining the photoelectric effect with the concept of particle-like photons. In 1969 Crisp and Jaynes(IO) and Lamb and Scullyfl I) showed that the quantum nature of the photoelectric effect can be explained with a classical radiation field and a quantum description for the atom. Photons do exist, but they only show up when the EM field is in a state that is an eigenstate of the number operator, and they do not reveal themselves in the photoelectric effect. 

Among the candidates considered for development in this series was the t-Bu amide which was subsequently given the name finasteride and became the active ingredient in both PROSCAR and PROPECiA (Figure 3.2). Section 3.1 will tell the story of the development of a manufacturing process for finasteride. As in most programs at Merck, dmg candidates showing potential for improved performance over the lead compound were approved for development as the lead... 

In a recent seminar, a medical expert noted that the United States has given away economic and technical dominance in industry after industry to other countries. Healthcare research is one of the few areas in which the U.S. enjoys unparalleled leadership which has enormous impact on the quality of medical care. If the healthcare industry and the academic medical enterprise falters—and this is in danger right now—I think it will be an absolute disaster for this country [40]. Many in pharmacy, medicine, and other healthcare fields would concur with the above statement. The problem is that many others in the public sector do not fully appreciate what is at stake. Pharmacists have an opportunity to help tell the story, as difficult as it sometimes is to convey. 

This book is about the scientific roots of our modern way of life. It tells the story of pioneering chemists like Berthollet whose discoveries solved critical problems in their lifetimes. Readers should be forewarned. The lives of these scientists tend to be dramatic. They are filled with the joys of discovery, the excitement of their times, and even the anguish of human tragedy. 

This book is extremely important in my view because it gives a forum to the voices and tells the stories of a new invisible minority who are casualties of our chemical-dependent economic base. Dr. Michael Tax, a specialist in occupational medicine, rightly insists that MCS is a product of industrial capitalism and cannot be understood independently of it. 

Two spirals as an art object for a public space -designed for the square in front of the city hall in Wiesbaden. The dates of historical events from the first millennium AD are engraved in the inner rim of the smaller spiral, dates telling the story of the second millennium are engraved in the larger one. Jets of water around the objects create rainbow spectra in the sunlight the pool is made of black granite. 

The history of racial classification over time is a second such site entire races have disappeared from view, from public discussion, and from modern memory, though their flesh-and-blood members still walk the earth. What has become of the nineteenth century s Celts and Slavs, for instance Its Hebrews, Iberics, Mediterraneans, Teutons, and Anglo-Saxons This book tells the story of how these races—these public fictions—rose and fell in American social consciousness, and how the twentieth century s Caucasians emerged to take their place. 

On 16 June 1786, the Cagliostros left Boulogne-sur-Mer on a boat bound for Dover. Cagliostros later memoir tells the story The shores that I quitted were lined by a crowd of citizens of all classes, who blessed and thanked me for the good I had done their brethren, addressing to me the most touching of farewells. The winds carried me far away from them, and I heard them no more. ... 

The selection process was initiated by a local announcement that a team from Edgewood Arsenal was coming to describe their research program. Higher authorities ordered commanders to set aside suffrcient time at the Post auditorium for would-be volunteers to complete applications, but only if they wished. From 500-1,000 curious soldiers usually showed up. An Edgewood physician would be there to tell the story of our program and show a movie of the facility and testing procedures. After that, those who were interested completed the required forms. 

D Writing on Your Own Tell the Story of Scientific Discovery... 

This book tells the story of the ubiquitin system as we currently know it from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, from X-ray crystallography of the 26S proteasome to the interaction between substrates and their ligases, to the development of mechanism-based drugs, and to target-specific aberrant processes. 

I will sketch briefly my personal academic history that prepared me to discuss these matters and then tell the story of how in the the summer of 1951 I hit upon and named A-representability. ... 

Hewitt, Bill. A Separate Peace Dismayed by Violence on the Streets, a New York Businessman Offers to Swap Ttys for Guns and Starts a Disarmament Crusade Across the Country. People Weekly, vol. 41, January 17, 1994, pp. 84ff. Tells the story of carpet store owner Fernando Mateo, Sr. Dismayed by media reports of violent deaths just before Christmas in 1993, Mateo hit upon the idea of organizing a program to swap toys for... 

Bogus, Carl T. NRA Money, Firepower, and Fear. Tikkun, January/Feb-ruary 1994, pp. 79ff. Autobiographical article that tells the story of a prominent attorney who became a convert to the cause of gun control after he was shot by a disturbed client. At first he tries to mediate between gun control supporters and the NRA, but he concludes that gun supporters are intransigent and that only a massive political mobilization of gun control advocates will achieve the necessary objective of restricting guns to only a few categories of people. 

Forman s life-writings narrate his first forty years, the period for which few papers survive. During these years Forman outfitted himself with the skills and attitudes with which he was equipped when he settled in London in 1591 and embarked on his career as a notorious astrologer-physician. In order to tell the story of Forman s childhood thirst for knowledge, ill-fated possession of books, and study of the occult, I first need to establish the dates and contents of each of the six texts which Forman devoted solely to his own life. 

Bren, Linda. Frances Oldham Kelsey FDA Medical Reviewer Leaves Her Mark on History. FDA Consumer 35, no. 2 (March/April 2001) 24-29. This article tells the story behind Kelsey s actions to block the approval of thalidomide and prevent the epidemic of birth defects that occurred in Europe from playing out in the United States. When working for the FDA, she demanded better studies of the drug s long-term safety, after which evidence of harm from Europe emerged and justified her careful approach. 

Invented by Bruce Roth in the late 1980s and now sold by Pfizer, the anticholesterol drug Lipitor became the world s best-selling drug. This article tells the story of the drug s development and success. 

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