Telemetry-based systems

The guinea pig has been shown to demonstrate drag-induced effects on the QT interval duration (Hamlin et al. 2003) and is suitable for use with telemetry-based systems. However, their intolerance of arterial catheters limits their use for simultaneously measuring arterial blood pressure. 

Automation System A system based on a computer technology with input devices (e.g., sensors), output devices (e.g., actuators), and communication links (e.g., telemetry and cable networks) that are collectively designed to perform a specific function or group of functions (e.g., control, protection or monitoring). Automation systems may be linked into larger integrated systems. [Defined for this book.]... 

The system consisted of a small 2.5-liter superinsulated vessel, a thermal control circuit, a pressure control loop, fluid temperature and pressure conditioning circuits, and telemetry components to monitor inflight performance. The flight system was thoroughly tested under atmospheric conditions to obtain a statistically accurate earthbound-performance base for comparative analysis of system operation in zero gravity. 

The system architecture utlized within the chemical detection, warning and reporting system installed at APG s CAS Y is based upon a simple star topology, consisting of a central hub with a suite of remote distributed processing nodes (see fig 1). The central hub contains the CPIMS as well as several components of the response subsystem. The equipment located within the central hub consists primarily of a telemetry interface and a central computer with display. All of this hardware is then tied into an uninteruptable power supply to support critical operations in the event of power loss. The central hub is usually located in a central operations or emergency response center. 

For the system installed at APG, there were no existing telephone lines between the CPIMS and the remote processing nodes. Also, the amount of RF traffic on the allocated frequency was minimal thereby not presenting a major concern for contention. Based upon this, a RF telemetry link was selected. 

There are cases when a dedicated CV telemetry study may be the best option to assess target liability concerns for BPs. These include the presence of the therapeutic target in the CV system (e.g., cardiac myocytes, vascular endothelium, or vascular smooth muscle) or the emergence of CV findings in nonclinical toxicity studies or clinical trials. For example, observation of cardiac dysfunction in patients treated with trastuzumab, a mAb for treatment of breast cancer, prompted the sponsor to perform a long-term telemetry study in the cynomolgus monkey in attempts to model the human cardiac dysfunction (Klein and Dybdal 2003). Likewise, a novel ADC based on trastuzumab was evaluated in a dedicated NHP telemetry study to evaluate potential target-mediated CV effects (Poon et al. 2013). 

Power efficiency, defined as the ratio of the power delivered to load over the total power dissipation, is the most important parameter in designing power telemetry system. To optimize power efficiency under physical constraints, an accurate solution for power efficiency in terms of design parameters is desired. Earlier work in the literature provides power efficiency formulae based on linear models [106,107]. Although such linear models provide design insights, they are oversimplified for the purpose of optimization. In this section, an expression of the power efficiency is derived. Based on derivations, the optimal component values are obtained and the fundamental upper limit of the power telemetry is concisely represented as a function of the quality factor Q) and coupling coefficient. 

The telemetry feature was based on LO resonant network, C being the sensor s capacity. By adding an inductor, the LC response wonld change in accordance to the capacity change, which is driven by the pressnre changes, hi order to fabricate the indnctor, a series of coils were printed on a flexible printed circnit, which serve as antenna to interrogate the sensor capacity. The readout system measures the oscillation frequency of the LC resonant circuit created by sensors and inductive coupling (Ohveira et al., 2015). 

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