Tartar emetic Potassium

Cause dermatitis, conjunctivitis and ulceration. Several salts (e.g. tartar emetic potassium antimony tartrate) have been used therapeutically as parasiticides. The dark cosmetic Kohl is finely powdered antimony sulphide. Stibine poisonous gas SbHj, produced by action of acid on antimony residues, such as can occur in storage batteries. Nausea, vomiting, colic, can be fatal. Stibine produces liver damage and jaundice, as does arsine. 

Potassium Antimonyl Tartrate (Tartar Emetic). C4H40 KSb0,... 

Tartaric acid is noteworthy for a) the excellent way in which the majority of its salts Crystallise, and h) the frequent occurrence of salts having mixed cations. Examples of the latter are sodium potassium tartrate (or Rochelle salt), C4H40 NaK, used for the preparation of Fehling s solution (p. 525), sodium ammonium tartrate, C4H OaNaNH4, used by Pasteur for his early optical resolution experiments, and potassium antimonyl tartrate (or Tartar Emetic), C4H404K(Sb0). The latter is prepared by boiling a solution of potassium hydrogen tartrate (or cream of tartar ) with antimony trioxide,... 

For the production of tartar emetic (antimony potassium tartrate [28300-74-5]), potassium bitartrate [868-14 ] and antimony oxide, Sb202, are added simultaneously to water in a stainless-steel reactor. The reaction mixture is diluted, filtered, and collected in jacketed granulators where crystallization takes place after cooling. Centrihiging, washing, and drying complete the process. 

Antimony potassium tartrate (tartar emetic) has the advantage of being low in cost. It has been called the dmg of choice for Schistosoma japonicum infection (204) even though it fails to cure the disease in many patients. However, trivalent antimonials are no longer recommended for the treatment of helminthic infections because these compounds have an unacceptable toxicity and are too difficult to administer (205). 

Antimony compounds have been used to treat leishmaniasis ever since tartar emetic (antimony potassium tartrate) was discovered early in the 20th century to have efficacy against the mucocutaneous form of the disease. The cutaneous form has been treated with tartar emetic formulated in an ointment. Many side effects have been seen with this trivalent antimonial, some of which can be ascribed to the difficulty of obtaining pure antimony for its manufacture. These side effects include toxicity to the heart, Hver, and kidneys. Other promising trivalent antimonials have been abandoned in favor of pentavalent antimonials with lower toxicity. 

Kaiium, n. potassium, -alatm, m. potassium alum, -azetat, n. potassium acetate, -bor-fluorid, n. potassium fluoborate. -brech-weinstein, m. antimonyl potassium tartrate, tartar emetic. 

AntimonyCIII) phosphate, 3 65 Antimony potassium tartrate (tartar emetic), 3 66 Antimony red, 3 44 Antimony selenide, 3 57 Antimony sesquioxide. See Antimony trioxide... 

It is oxidized to antimony pentoxide, 86205 on treatment with nitric acid and forms potassium antimony tartrate (tartar emetic, KSb(OH)2 C4H2O6) when heated with acid potassium tartrate. 

G. Taddei7 prepared potassium iodide by adding a dil. soln. of potassium monosulphide to an alcoholic soln. of iodine. In place pf potassium sulphide, J. von Liebig and C. Wittstock used barium sulphide, prepared by calcining sulphate with coke. According to R. Schindler, the products obtained by the sulphide process are contaminated with sulphur compounds. G. S. Serullas treated potassium antimoniate (prepared by calcining tartar emetic) with an alcoholic soln. of iodine as long as the soln. was decolorized. The filtered soln. was evaporated to the point of crystallization. 

A solution of 0.2g-0/3g of potassium antimonyl tartrate (tartar emetic) in 100ml of water Is treated with hydrogen sulfide for a short time An orange-yellow sol is formed which is dialysed in running water for 2-4 days ... 

J. Puffin and P. Rend, Antimoine Anti-biotique The public fortunes of the secret properties of antimony potassium tartrate (tartar emetic) , J. Hist. Med., 1991, 46, 44(M56. 

SYNS ANTLMONYL POTASSIUM TARTRATE EMETIQUE (FRENCH) ENT 50,434 POTASSIUM ANTIMONYL TARTRATE Q POTASSIUM ANTIMONYL-d-TARTRATE POTASSIUM ANTIMONY TARTRATE TARTAR EMETIC TARTARIZED ANTIMONY TARTRATE ANTIMONIO-POTASSIQUE (FRENCH) TARTRATED ANTIMONY... 

Potassium amimonyl tartrate tartar emetic, KSbOC H Og) and some other compounds of antimony are used in medic ine. 

Mordant pieces of test fabric by allowing them to stand in a hot (nearly boiling) solution of 0.1 g of tannic acid in 50 mL of water for 30 min. The tannic acid mordant must now be fixed to the cloth otherwise it would wash out. For this purpose, transfer the cloth to a hot bath made from 20 mg of potassium antimonyl tartrate (tartar emetic) in 20 mL of water. After 5 min, wring the cloth and dry it as much as possible over a warm hot plate. 

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