Target identification, drug discovery methods

Jurgen Moll and Riccardo Colombo (eds.), Target Identification and Validation in Drug Discovery Methods and Protocols, Methods in Molecular Biology, vol. 986, DO110.1007/978-1 -62703-311 -4 1, Springer Science+Business Media New York 2013... 

The identification of compounds with a desired property is a central pursuit in science. In the field of drug discovery combinatorial chemistry has played an increasingly important role for identification and optimization of drug leads which target therapeutically important biomolecules. For the successful implementation of combinatorial methods, new and innovative synthesis methods have been developed. Additionally, novel conceptual approaches to the design of compounds have been pursued to more efficiently generate libraries of small molecules. 

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