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Target discovery targets

Target discovery, to identify genes or pathways with altered expression in diseased human tissues or in animal model of disease... [Pg.528]

Hsu JT, Wang HC, Chen GW et al (2006) Antiviral drug discovery targeting to viral proteases. Curr Pharm Des 12 1301-1314... [Pg.1287]

Most drug discovery targets fit into one of the target families shown in Fig. 1. Included in the figure is the distribution of the market share by target family. [Pg.37]

Atpein EngeneOS Motorola Life Sciences. Target Discovery. [Pg.229]

Walker MG et al. Pharmaceutical target discovery using Guilt-by-Association schizophrenia and Parkinson s disease genes. ISMB 1999 282-286. [Pg.117]

Watkins, L. R. and Maier, S. F. Glia a novel drug discovery target for clinical pain. Nat. Rev. DrugDiscov. 2 973-985,2003. [Pg.937]

FIGURE 1 Selection of the HIV protease as a drug discovery target. Demonstration that inactivation of the HIV protease interferes with HIV infectiv-ity. Immunoblot of HIV proteins in mock-transfected cells (lane 1), cells transfected with HIV containing active protease (lanes 2 and 4), and cells transfected with HIV in which the protease was inactivated. Reprinted with permission from ref. 8 (copyright Kohl et al). [Pg.195]

M. F. Browner, Matrix Metalloproteases Structure-Based Drug Discovery Targets , Perspect. Drug Discov. Design 1995, 2, 343-351. [Pg.94]

DRUG DISCOVERY TARGETS AND RECEPTORS Drug Interactions with Targets or Receptors 30... [Pg.20]


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A Systems Biology Approach to Target Identification and Validation for Human Chronic Disease Drug Discovery

Bioinformatics target discovery

Biologicals Are the Low Hanging Fruit of Genomics-Based Target Discovery

Cancer proteomics target discovery

Chemistry-driven target discovery

DRUG DISCOVERY TARGETS AND RECEPTORS

Discovery Targets and Receptors

Discovery research making target compounds

Discovery research suitable target compounds

Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers, First Edition. Edited by Yvonne Will. J. Eric McDuffie

Drug discovery validated disease target

Epigenetic Targets in Drug Discovery Cell-Based Assays for HDAC Inhibitor Hit Validation

Influenza Virus Sialidase A Target for Drug Discovery

Influenza Virus Sialidase as a Drug Discovery Target

Insects discovery targets

Multi-target drugs discovery

Organizing Bioactive Compound Discovery in Target Families

Target Validation The Foundation of Drug Discovery

Target discovery

Target discovery

Target drug discovery process

Target identification, drug discovery

Target identification, drug discovery genes

Target identification, drug discovery methods

Target validation, drug discovery

Target, targets drug discovery

Target-Based antimicrobial drug discovery

Target-based drug discovery

Targeted Design and Open-Ended Discovery

Targets drug discovery

Virus Sialidase as a Drug-Discovery Target

Weeds discovery targets

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