Drug target identification

Skin Diseases in Laboratory Mice Approaches to Drug Target Identification and Efficacy Screening... 

Campillos M, Kuhn M, Gavin A, Jensen L, Bork P (2008) Drug target identification using side-effect similarity. Science 321 263-266... 

Noble, D. and Colatsky, T. J. A return to rational drug discovery computer-based models of cells, organs and systems in drug target identification. Emerging Therapeutic Targets 2000, 4 39 49. 

Michelson S., Scherrer D., Bangs A. Target Identification and Validation Using Human Simulation Models. In In Silico Technologies in Drug Target Identification and Validation, Eds. Leon, D. and Markell, S. Taylor Francis, 2006. 

Wang X, Jiang H. PDTD a web-accessible protein database for 37. drug target identification. BMC Bioinf. 2008 9 104. 

Drug target identification and validation by proteomics (discovery of novel, biologically active molecules and validation of drug targets)... 

Experimental design for large-scale gene expression studies and drug target identification 120... 

FIGURE 1.1 In silico technologies and supported methods for drug-target identification and validation. 

In Silico Technologies in Drug Target Identification and Validation... 

Chapter 2—Pattern Matching Using a variety of pattern-matching approaches is essential for any basic nucleotide sequence analysis and protein function determination. Markel and Rajapakse review the key motif, domain, and pattern databases and tools commonly used in drug target identification projects. 

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