Swiss Institute

The SWISS-PROT database [36] release 40.44 (February, 2003) contains over 120 000 sequences of proteins with more than 44 million amino adds abstracted from about 100 000 references. Besides sequence data, bibHographical references, and taxonomy data, there are highly valuable annotations of information (e.g., protein function), a minimal level of redundancy, and a high level of integration with other databases (EMBL, PDB, PIR, etc.). The database was initiated in 1987 by a partnership between the Department of Medicinal Biochemistry of the University of Geneva, Switzerland, and the EMBL. Now SWISS-PROT is driven as a joint project of the EMBL and the Swiss Institute of Bioinformatics (SIB). 

Swiss Prot EMBL and Swiss Institute of Bioinformatics protein sequence biblio., sub- stance, se- quence 120000 protein sequences, 44 mio amino adds journals, author submis- sions European Bioinformatics Institute free periodi- cally http //www.e- bi.ac.uk/swis- sprot/in- dex.html... 

Marmara University, Division of Pediatric Allergy and Immunology, Istanbul,Turkey, and Swiss Institute of Allergy and Asthma Research (SIAF), Davos, Switzerland... 

Friedrich Beermann Swiss Institute for Experimental Cancer Research (ISREC) Epalinges, Switzerland... 

The Swiss-Prot database is probably the most widely used protein database. It is maintained collaboratively by the European Bioinformatics Institute (EBI) and the Swiss Institute for Bioinformatics. It is relatively easy to access and search via the World Wide Web (Table 2.4). A sample entry for human insulin is provided in Figure 2.4. Additional information detailing such databases is available via the web addresses provided in Table 2.4 and in the bioinformatics publications listed at the end of this chapter. 

Guex, N., Diemand, A., Peitsch, M. C. and Schwede, T. Deep ViewSwissPdb Viewer. Basel Swiss Institute ofBioinformatics, 2001. Available on line at www.expasy.org/spdbv/. 

SwissProt (http //www.expasy.org/sprot), database established by the Swiss Institute of Bioinformatics, provides protein sequences with high level of annotation. Highly integrated with other protein databases. All data are verified manually. 

Board of the Swiss Federal Institutes of Technology (1998). 2000 Watt Society - Swiss Model. Sustainability Strategy within the Swiss Institutes of Technology (in German). Wirtschaftsplattform. ETH Zurich. 

SWISS-PROT (Bairoch and Apweiler, 1999) is an annotated protein sequence database established in 1986 and maintained collaboratively by the Swiss Institute of Bioinformatics and the EMBL Outstation, The European Bioinformatics Institute (EBI). It strives to provide a high level of annotation, a minimal level of redundancy, a high level of... 

CC This SWISS-PROT entry is copyright. It is produced CC through a Collaboration between the Swiss Institute of CC Bioinformatics and the EMBL outstation - the European CC Bioinformatics Institute. There are no restrictions on CC its use by non-profit institutions as long as its content CC is in no way modified and this statement is not removed. 

While the FDA is adopting a cautious approach to cancer vaccine, such as DCVax-Brain, the Swiss Institute of Public Health has conditionally allowed the use of this vaccine by patients. DCVax consists of a patient s dendritic cells that have been pulsed with antigens derived from a tumor cell lysate prepared from surgically resected glioblastoma (brain cancer) tissue. It was developed by a company in the United States but has not yet been approved by the FDA. 

Proteomics server of the Swiss institute of bioinformatics. Dedicated to analysis of protein sequences and structure, as well as 2-D SDS-PAGE. 

Bonomo M, Mingrone W, Brauchli P, Hering F, Goldhirsch A Swiss Group for Clinical Cancer Cancer Research, a member of the Swiss Institute of Applied Cancer Research. Exemestane seems to stimulate tumour growth in men with prostate carcinoma. Eur J Cancer 2003 39(14) 2111-2. 

The present book is rooted in a lecture on chemical process safety at graduate level (Masters) at the Swiss Federal Institute of Technology in Lausanne. It is also based on experience gained in numerous training courses for professionals held at the Swiss Institute for the Promotion of Safety Security, as well as in a number of major chemical and pharmaceutical companies. Thus it has the character of a textbook and addresses students, but also addresses professional chemists, chemical engineers or engineers in process development and production of fine chemicals and pharmaceutical industries, as support for their practice of process safety. 

Swiss Institute for http //www.ebi.ac.uk/genomes Dedicated to analysis... 

SWISS-PROT (Bairoch and Apweiler, 2000) is a protein sequence database that, from its inception in 1986, was produced collaboratively by the Department of Medical Biochemistry at the University of Geneva and the EMBL. The database is now maintained collaboratively by Swiss Institute of Bioinformatics (SIB) and EBI/EMBL. SWISS-PROT provides high-level annotations, including descriptions of the function of the protein and of the structure of its domains, its post-translational modifications, its variants, and so on. The database can be accessed from http //expasy.hcuge.ch/sprot/sprot-top.html or numerous mirror sites. In 1966, Translated EMBL (TrEMBL) was created as a computer-annotated supplement to SWISS-PROT (Bleasby et al, 1994). 

SWISS-PROT (Hofmann et al., 1999) is a curated protein sequence database maintained by the Swiss Institute of Bioinfornmatics and is a collaborative partner of EMBL. The database consists of SWISS-PROT and TrEMBL, which consists of entries in SWISS-PROT-like format derived from the translation of all CDS in the... 

The known functional sites are described in the FEATURE lines of the annotated sequence hies such as PIR, GenPept, and Swiss-Prot. The PRO SITE database (http //www.expasy.ch/sprot/prosite.html) consists of biologically significant patterns/prohles/signatures that may aid in identifying the query sequence to the known family of proteins (Hofmann et al., 2000). The database that is composed of two ascii (text) hies, PROSITE.dat and PROSITE.doc, can be downloaded using FTP from ExPASy (ftp //www.expasy.ch/databases/prosite/) or Swiss Institute for... 

HAMAP Swiss Institute of Bioinformatics Database of completely sequenced microbial proteome sets and manually curated microbial protein families in UniProtKB/Swiss-Prot (http //hamap.expasy.org/)... 

In July 2007, a US biotech firm, Northwest Biotherapeutics, received approval form the Swiss Institute of Public Health to market to selected centers in Switzerland the first brain cancer vaccine, DCVax-Brain , an autologous patient-specific dendritic cell based vaccine. 

ExPASy is a database maintained by the Swiss Institute of Bioinformatics (SIB) that is dedicated to the organization of protein sequences. ISREC is a similar database maintained by the Bioinformatics Group... 

Swiss Institute for Alternatives to Animal Testing Aeschstrasse 14... 

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