Databases sites

Pesticide Database site - by Pesticide Action Network North America (PAN). Online. Available HTTP (accessed 4 April 2003). 

At your selected database site, follow links to locate the sequence comparison engine. Enter about 30 residues from the sequence of the protein in the appropriate search field and submit it for analysis. What does this analysis tell you about the identity of the protein ... 

Databases. Sites such as Bath Information and Data Services (BIDS) and web of Science (WOS) provide access to abstracts of recent publications use these to find relevant literature for specific topics. Access is via the websites at http //www.bids.ac.uk/ or http //www.webofscience.com you will need a username and password - check with your department or library. In the case of BIDS, it provides access to databases covering subjects from science, engineering and medicine to economics, politics, education and the arts. Specific databases offered include ISI citation indexes EMBASE (international biomedical information) INSPEC (physics, electronic engineering and computing) international bibliography of the social sciences (IBSS) The Royal Society of Chemistry databases and education databases. See also Table 46.2. 

TABLE 14.11 Some primary database sites of biochemical interest... 

J. S. Brecher, Chem. Ind., 1996, 23, 22-23 a comprehensive list of database sites can be found at the following URL http //chemfinder.camsoft.com/siteslisLhtml... 

Usually an Internet user learns after a while where to go for specific information The Browser provides a bookmark tlmction where all these addresses can be organized by different subjects Typical bookmark folders are Societies, Companies, Journals, Institutes, Databases, Search engines The NDTnet Journal provides a virtual library that makes it easy for newcomers to find NDT sites. Unfortunately, some sites provide a lot of information but do not offer a search function. 

WWW NDT/UT Library of 250 sites with its abstracts in sections Institutes. Societies. Applications, Databases/Archives, Standards. NDT Maps of Germany/Canada/Israel... 

The JME Editor is a Java program which allows one to draw, edit, and display molecules and reactions directly within a web page and may also be used as an application in a stand-alone mode. The editor was originally developed for use in an in-house web-based chemoinformatics system but because of many requests it was released to the public. The JME currently is probably the most popular molecule entry system written in Java. Internet sites that use the JME applet include several structure databases, property prediction services, various chemoinformatics tools (such as for generation of 3D structures or molecular orbital visualization), and interactive sites focused on chemistry education [209]. 

Choose relevant sites or databases directly (metadatabases), and always nsc more than one search service. 

Reactions can be considered as composite systems containing reactant and product molecules, as well as reaction sites. The similarity of chemical structures is defined by generalized reaction types and by gross structural features. The similarity of reactions can be defined by physicochemical parameters of the atoms and bonds at the reaction site. These definitions provide criteria for searching reaction databases [23],... 

If it is known that a drug must bind to a particular spot on a particular protein or nucleotide, then a drug can be tailor-made to bind at that site. This is often modeled computationally using any of several different techniques. Traditionally, the primary way of determining what compounds would be tested computationally was provided by the researcher s understanding of molecular interactions. A second method is the brute force testing of large numbers of compounds from a database of available structures. 

Other excellent summaries describing what is known of the formation processes and geological setting of these deposits have also been assembled (30—32). Listings of nodule compositions for these and other areas have been compiled (33,34). Eor many sites these data are available as computer databases (qv) maintained by the NOAA National Geophysical Data Center in Boulder, Colorado. 

There are very sophisticated programs to search these databases. The databases are used by chemists to design new chemical compounds and by dmg companies to design new dmgs for a great variety of diseases. Of special interest is the design of dmgs that fit into the active sites of proteins. 

Published Cost Correla.tions. Purchased cost of an equipment item, ie, fob at seller s site or other base point, is correlated as a function of one or more equipment—size parameters. A size parameter is some elementary measure of the size or capacity, such as the heat-transfer area for a heat exchanger (see HeaT-EXCHANGETECHNOLOGy). Historically the cost—size correlations were graphical log—log plots, but the use of arbitrary equation forms for correlation has become quite common. If cost—size equations are used in computer databases, some limit logic must be included so that the equation is not used outside of the appHcable size range. 

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