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SWi / SNF

Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E (2006) The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. J Biol... [Pg.114]

Pereira LA, Bentley K, Peelers A, ChurchiU MJ, Deacon NJ (2000) A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter. Nucleic Acids Res 28(3) 663-668 Persaud D, Zhou Y, Siliciano JM, Siliciano RF (2003) Latency in human immunodeficiency virus type 1 infection no easy answers. J Virol 77(3) 1659-1665 Peterson CL, Tamkun JW (1995) The SWI-SNF complex a chromatin remodeling machine Trends Biochem Sci 20(4) 143-146... [Pg.115]

Treand C, du Chene I, Bres V, Kieman R, Benarous R, Benkirane M, Emdiani S (2006) Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter. EMBO J 25(8) 1690-1699... [Pg.117]

WUson CJ, Chao DM, Imbalzano AN, Schnitzler GR, Kingston RE, Young RA (1996) RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodeling. Cell 84(2) 235-244... [Pg.117]

Neely, K.E. et al. (2002) Transcription activator interactions with multiple SWI/SNF subunits. Mol. Cell. Biol. 22(6), 1615-1625. [Pg.1097]

Zhao K, Wang W, Rando OJ, Xue Y, Swiderek K, Kuo A, Crabtree GR (1998) Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell 95 625-636... [Pg.29]

Several links have emerged between remodelling factors and oncogenesis (reviewed in Cairns, 2001). Subunits of the mammalian SWI/SNF complex possess intrinsic tumour suppressor function or are required for the activity of other... [Pg.33]

Helicases catalyze the processive separation of duplex DNA into single strands. Despite sharing similarity to helicases, none of the chromatin remodelling factors, with the exception of the INO80 complex, have been shown to catalyze the separation of DNA strands (Shen et al, 2000). Instead, they can translocate on double-stranded (ds) DNA in an ATP-hydrolysis dependent manner and are characterized by their ability to generate superhelical torsional strain in DNA (Havas et al, 2000 Saha et al, 2002 Whitehouse et al, 2003). The crystal structure of Rad54, a member of the SWI/SNF family has been solved for both S. solfataricus and zebrafish which helps to understand the mechanism of the SWI/SNF ATPase domain in remodelling processes (Durr et al, 2005 Thoma et al, 2005). It reveals... [Pg.34]

Pray-Grant MG, Daniel JA, Schieltz D, Yates JR, 3rd, Grant PA (2005) Chdl chromodomain links histone H3 methylation with SAGA- and SLlK-dependent acetylation. Nature 433 434-438 Rando OJ, Zhao K, Janmey P, Crabtree GR (2002) Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-hke BAF chromatin remodehng complex. Proc Natl Acad Sci USA 99 2824-2829 Roberts CW, Orkin SH (2004) The SWI/SNF complex - chromatin and cancer. Nat Rev Cancer 4 133-142... [Pg.43]

Whitehouse 1, Stockdale C, Haus A, Szczelkun MD, Owen-Hughes T (2003) Evidence for DNA translocation by the ISWl chromatin-remodeling enzyme. Mol Cell Biol 23 1935—1945 Wong AK, Shanahan E, Chen Y, Lian L, Ha P, Hendricks K, Ghaffari S, lliev D, Penn B, Woodland AM et al (2000) BRG1, a component of the SWI-SNF complex, is mutated in multiple human mmor cell lines. Cancer Res 60 6171—6177... [Pg.44]

Angelov D, Molla A, Perche PY, Hans F, Cote J, Khochbin S, Bouvet P, Dimitrov S (2003) The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling. Mol Cell 11 1033-1041... [Pg.84]

Angelov D, Verdel A, An W, Bondarenko V, Hans F, Doyen CM, Studitsky VM, Hamiche A, Roeder RG, Bouvet P, Dimitrov S (2004) SWI/SNF remodeling and p300-dependent transcription of histone variant H2ABbd nucleosomal arrays. Embo J 23 3815-3824... [Pg.84]

Figure 1. Nucleolin acts as a histone chaperone and boosts the activity of chromatin remodeler SWI/SNF. (a) In vitro histone deposition assay shows the histone chaperone activity of nucleolin. Recombinant core histones were incubated with 5S 147 bp DNA in presence or absence of nucleolin. Note the disappearance of aggregates in the wells and the formation of nucleosomal particles in presence of increasing amount of nucleolin. (b) Sliding assay performed on centrally positioned 601 nucleosomes (250bp). The amount of SWI/SNF used here is insufficient to slide the nucleosomes. Note that in presence of nucleolin even the suboptimal quantity of SWI/SNF is able to slide the nucleosomes... Figure 1. Nucleolin acts as a histone chaperone and boosts the activity of chromatin remodeler SWI/SNF. (a) In vitro histone deposition assay shows the histone chaperone activity of nucleolin. Recombinant core histones were incubated with 5S 147 bp DNA in presence or absence of nucleolin. Note the disappearance of aggregates in the wells and the formation of nucleosomal particles in presence of increasing amount of nucleolin. (b) Sliding assay performed on centrally positioned 601 nucleosomes (250bp). The amount of SWI/SNF used here is insufficient to slide the nucleosomes. Note that in presence of nucleolin even the suboptimal quantity of SWI/SNF is able to slide the nucleosomes...
Martens JA, Winston E (2003) Recent advances in understanding chromatin remodeling by Swi/Snf complexes. Curr Opin Genet Dev 13 136-142... [Pg.142]

Peterson CL, Workman JL (2000) Promoter targeting and chromatin remodeling by the SWI/SNF complex. Curr Opin Genet Dev 10 187-192... [Pg.394]

In addition to a potential role of HMGB proteins in nucleosome assembly, it has recently become apparent that many chromatin remodeling complexes either contain, or can associate with, a polypeptide containing an HMG-box homologous to the HMGBl B domain (Table 2). Examples of such complexes include the BAF (a mammalian SWI/SNF related complex [106]) and the Drosophila BRM (brahma)... [Pg.115]


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SWI/SNF protein

Swi / Snf chromatin-remodeling

Swi / Snf chromatin-remodeling complex

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