Supramolecular functions

Nanosized supramolecular materials have received increasing attention during the last two decades. Their properties have been surveyed for their ability to form aggregates in the solution phase, which form channel-like arrays in the solid state, and which ultimately form single channels in planar bilayer membranes. These systems therefore illustrate, in general, the convergence of supramolecular selforganization and supramolecular function. 

Matile, S. (2001) En route to supramolecular functional plastidty synthetic P-barrels, the barrel-stave motif, and related approaches. Chemical Society Reviews, 30, 158-167. 

Real JA (1999) Bistability in iron(II) spin crossover systems a supramolecular function. In Sauvage JP (ed) Transition metals in supramolecular chemistry. Wiley, p 53... 

Toftlund H (1996) in Kahn O (ed) Magnetism A Supramolecular Function. NATO ASI Series C, Vol 484, Kluwer Academic, The Netherlands, p 323... 

Over the past 5 years, a number of researchers have started to explore and mimic these approaches in the laboratory. Enzyme-assisted formation of supramolecular polymers has several unique features. These include selectivity, confinement and catalytic amplification, which allow for superior control as observed in biological systems. These systems are finding applications in areas where supramolecular function is directly dictated by molecular order, for example in designed biomaterials for 3D cell culture, templating, drug delivery, biosensing, and intracellular polymerisations to control cell fate. Overall, biocatalytic production of supramolecular polymers provides a powerful new paradigm in stimuli-responsive nanomaterials. 

CHEMICAL SENSING BASED ON MEMBRANES WITH SUPRAMOLECULAR FUNCTIONS OF BIOMIMETIC AND BIOLOGICAL ORIGIN... 

CHEMICAL SENSING BASED ON THE SUPRAMOLECULAR FUNCTIONS OF BIOLOGICAL... 

In general, a supramolecular species possesses the following attributes (1) The intrinsic properties of the molecular components are not significantly perturbed and (2) the properties of the supramolecular system are not a simple superposition of the properties of the molecular components there is a supramolecular function [13]. Upon substitution of one of the molecular components by a semi-... 

Kahn, O., Magnetism a Supramolecular Function, NATO ASI Series, Kluwer, Dordrecht,... 

Molecular and supramolecular devices are by definition formed from covalently and non-covalently linked components, respectively. One might envisage that covalently built devices made up of distinct but interacting components, retaining at least in part their identity as if they were bound together in a non-covalent fashion, could also belong to the supramolecular domain. Such a case has been argued for supramolecular photochemistry [A. 10] and could be extended to other supramolecular functions. 

Lehmann M (2009) Star mesogens (Hekates) - tailor-made molecules for programming supramolecular functionality. Chem Eur J 15 3628-3651... 

AZAMACROCYCLIC SYSTEMS WITH DIFFERENT SUPRAMOLECULAR FUNCTIONS... 

The discussed examples clearly demonstrate the importance of azamacrocycles as structural element to create supramolecular function. Their rigid structure, the basicity and transition metal-ion coordinating ability make them suitable as scaffolds and binding sites. Lanthanide chemosensors containing azamacrocyclic ligands have already reached applications in medical diagnostics. Other applications of azamacrocyclic systems with supramolecular functions, particularly in biochemistry, will follow. 

Real, Jose Antonio, Bistability in Iron (II) Spin-Crossover Systems A Supramolecular Function, 5, 53. 

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