Supercritical fluid chromatography-Fourier

Supercritical Fluid Chromatography/Fourier Transform Mass Spectrometry," Anal. Chem., , 1309-1312 (1987). 

Note that Jenke " also cites references to the use of other related analytical techniques, including Head-space GC, high performance thin layer chromatography (HPTLC), supercritical fluid chromatography (SFC) /MS, and supercritical fluid chromatography/ Fourier transform infrared spectroscopy (SFC/FTIR). 

M. W. Raynor, K. D. Bartle, I. L. Davies, A. Williams, A. A. Clifford, J. M. Chalmers, and B. W. Cook, Polymer additive characterization by capillary supercritical fluid chromatography/Fourier transform infrared microspectrometry, A aZ. Chem. 60 427-433 (1988). 

Supercritical Fluid Chromatography-Fourier Transform Infrared Spectrometry. 773... 

Norton KL and Griffiths PR (1995) Performance characteristics of a real-time direct deposition supercritical fluid chromatography-Fourier transform infrared spectrophotometry system. Journal of Chromatography A 703 503-522. 

Supercritical fluid chromatography Thin-layer chromatography Atomic absorption spectroscopy Nuclear magnetic resonance spectroscopy Mass spectrometry Fourier transform infrared spectrometry... 

Non-ionic surfactants of a commercial washing powder were separated by supercritical fluid chromatography (SFC) and determined by APCI-MS. The constituents were first extracted by supercritical fluid extraction (SFE) using C02 with or without methanol as a modifier. Variations of the conditions resulted in a selective extraction of the analytes, which could be determined without further purification. Six groups of surfactants were observed, four of which are alkyl-polyethoxylates. The presence of APEO could be excluded by identification recording SFC-FTIR (Fourier transform infrared) spectra [31]. 

Hadj-Mahammed, M., Badjah-Hadj-Ahmed, Y., and Meklati, B.Y., Behavior of pol5nnethoxy-lated and polyhydroxylated flavones by carbon dioxide supercritical fluid chromatography with flame ionization and Fourier transform infrared detectors, Phytochem. Anal, 4, 275, 1993. 

Several researchers have combined the separating power of supercritical fluid chromatography (SFC) with more informative spectroscopic detectors. For example, Pinkston et. al. combined SFC with a quadrupole mass spectrometer operated in the chemical ionization mode to analyze poly(dimethylsiloxanes) and derivatized oligosaccharides (7). Fourier Transform infrared spectroscopy (FTIR) provides a nondestructive universal detector and can be interfaced to SFC. Taylor has successfully employed supercritical fluid extraction (SFE)/SFC with FTIR dectection to examine propellants (8). SFC was shown to be superior over conventional gas or liquid chromatographic methods. Furthermore, SFE was reported to have several advantages over conventional liquid solvent extraction (8). Griffiths has published several... 

Although not used in any of the overall methods found, Fourier transform-infrared spectroscopy for detection after GC can supplement MS to verify the presence of DNOC in samples (Budzinski et al. 1992 Gurka et al. 1991 Schneider et al. 1991). Alternative separation methods have also been shown to be applicable to nitrophenols, including DNOC, but have not yet become routine. These methods include supercritical fluid chromatography (Ong et al. 1992 Pospisil et al. 1992), capillary zone electrophoresis (Chao and Whang 1994), and micellar electrokinetic chromatography (Ong et al. 1991). 

Traditionally, flavonoids have been separated and analyzed by HPLC and gas chromatography (GC). However, recent developments of SFC may permit a more accurate and complete analysis of plant phenolic compounds. Supercritical fluid chromatography brings together the advantages of both HPLC and GC techniques because it may be readily employed in the analysis of nonvolatile and thermolabile compounds and provides facile coupling to detector technologies such as mass spectrometry and Fourier transform infrared (FT-IR) spectroscopy. In recent years, SFC has been used to separate flavonoid compounds, most of which are polymethoxylated flavones and polyhydroxylflavonoids. 

Bartle, K.D., M.W. Raynor, A.A. Clifford, I.L. Davies, J.P. Kithinji, G.F. Shilstone, J.M. Chalmers, and B.W. Cook. 1989. Capillary supercritical fluid chromatography with Fourier transform infrared detection. J. Chromatogr. Sci. 27 283-292. 

Supercritical Fluid Chromatography with Fourier Transform Infrared Detection... 

Infrared spectroscopy is probably the most widespread analytical spectroscopic technique for identification and characterization of organic compounds. Because of this identification capability infrared spectroscopy is desirable as a detection technique for chromatographic separations. With the advent of Fourier transform infrared spectroscopy/ the speed and sensitivity of infrared detection is greatly enhanced making such applications feasible. FT-IR detection has been widely accepted as a detector for gas chromatography (GC/FT-IR) (1) and has been applied with limited success to liquid chromatography (LC/FT-IR) (2)/ and more recently to supercritical fluid chromatography (SFC/FT-IR) (3). The recent review articles cited here provide excellent introduction and references to current state-of-the-art in these areas. 

Supercritical fluid chromatography (SEC) coupled with Fourier transform infrared spectroscopy has been used to determine polymeric surfactants in various polymers [56, 57]. 

Fuoco R, Pentoney L and Griffiths PR (1989) Comparison of sampling techniques for combined supercritical fluid chromatography and Fourier transform infrared spectrometry with mobile phase elimination. Analytical Chemistry 61 2212-2218. 

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