Sulphur derivatives

Hughes and his co-workers have reported the preparation of three types of thio-sugar derivatives. The strong preference of 5-thio-D-ribose and 5-thio-D-xylose for ring-closure on to sulphur is shown by the formation of the strained 1,2 3,4-diacetals (188) and (189) in the reactions with acetone and 2,2-dimethoxy- 

6-dimethanesulphonates of D-mannitol or galactitol reacted with sodium sulphide at pH 8—10 to give the corresponding 1,6-thioanhydrohexitols [e.g. (200)].  

Olivier-Fourcade, E. Philippot, and M. Maurin, Acta Cryst., 1974, B30, 1391. 

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Te2Fio, and oxide fluorides, e.g. TeFjOTeFs, are also formed during the fluor-ination of tellurium oxides, tellurium, organic derivatives Tellurium forms organic derivatives in the +2 and +4 slates. The +2 compounds are similar to divalent sulphur derivatives although less stable. Tellurium(IV) derivatives are comparatively unstable. 

Petroleum Available in fractions of b.p. 40-60°, 60-80°, 80-100°, 100-120° yy Frequently called light petroleum or petrol ether. Unless specially purified, contains sulphur derivatives, etc.y as impurities. 

There are other sulphur derivatives which react violently. Lead peroxide combusts in contact with sulphuric acid. It forms an explosive mixture with sulphuryl chloride and incandesces in sulphur dioxide. 

G. Aromatic Nucleophilic Substitution with Amines in which the Nucleofuge is a Sulphur Derivative... 

At the same time and in the years to follow, several other groups reported the observation of high selectivities in the Pd-catalyzed resolution of racemic substrates [6]. The kinetic resolution depicted in Scheme 2.1.4.2 gives access to both the enantio-enriched allylic acetate and sulfone. Because of the many applications chiral allylic alcohols and allylic sulphur derivatives have found in the synthesis... 

Essential oils may comprise volatile compounds of terpenoid or non-terpe-noid origin. All of them are hydrocarbons and their oxygenated derivatives. Some may also contain nitrogen or sulphur derivatives. They may exist in the form of alcohols, acids, esters, epoxides, aldehydes, ketones, amines, sulphides, etc. Monoterpenes, sesquiterpenes and even diterpenes constitute the composition of many essential oils. In addition, phenylpropanoids, fatty acids and their esters, or their decomposition products are also encountered as volatiles [1-16, 21-33, 36-38]. 

Sulphur derivatives of 1-alkylsilatranes are commonly toxic46,47). Thus, 1-mercaptoalkylsilatranes26, 27 are almost 2 orders more toxic than the initial mercaptoalkyltrialkoxysilanes48 ... 

The simpler aliphatic sulphur derivatives considered in this section are the sulphur analogues of oxygen compounds, e.g. the thiols (RSH), and the symmetrical or unsymmetrical thioethers (R-S-R or R -S-R2). Compounds derived from these two groups, where the sulphur atom can attain a higher oxidation state, are the sulphinic and sulphonic acids (R-SO-OH and R-S02 OH), the sulphox-ides (R-SO-R), and the sulphones (R-S02-R). Other compounds of interest which are considered in the following discussion are ... 

The application of 33S NMR spectroscopy to the qualitative characterization of sulphur compounds in coals and petroleum has been another subject of a certain interest.99-10 The presence of organic and inorganic sulphur derivatives in variable amounts in fuels has serious economic and environmental consequences. Coals and crude oils can be treated chemically to reduce sulphur content, and it is of fundamental importance to develop an analytical method to rapidly and accurately analyse sulphur before and after the desulphurization process. 

The cyanide in cassava that is not properly prepared can be released by the action of enzymes in our gut and can poison an individual. It does this by binding to an enzyme in the mitochondria inside the cell which blocks the production of energy. In vulnerable tissues, like the nerves of the spinal cord, this causes damage. The detoxication of cyanide with sulphur, derived from sulphur-containing amino acids in protein, produces thiocyanate, which is excreted into the urine, but this system is easily overwhelmed especially in those deficient in sulphur. Drought and poor soil seem to increase the production of linamarin in cassava, and it is possible that other dietary deficiencies may contribute to the nerve damage. 

The investigation of potential perfumery compounds from manool has continued with the preparation of some 12-methylene derivatives [e.g. (30)]. A relatively stable ozonide (31) has been obtained from manool. The crystal structure of the ruthenium tetroxide oxidation product (32) obtained from manool has been determined. The sulphur derivatives of the perfumery acetals obtained from manool have been prepared. ... 

SULPHUR VITRIOLATUM — Sulphur derived from Vitriol by decoction in water, upon which it floats. 

Dichloroethyl ether, though very similar in its chemical properties to the sulphur derivative, has very different physio-pathological properties, being destitute of vesicant power. According to Hofmann this lack of vesicant power must be attributed to the fact that dichloroethyl ether, unlike dichloroethyl sulphide, cannot penetrate the epidermis. 

Amino-4-hydroxyphenylarsinic acid jields a sulphide when reduced by hydrogen sulpiride, but the composition of the siilphide does not appear to have been determined with certain. The sulpiride is soluble in acids aird alkalis, solutions in the latter on boiling with lead acetate gidng a black precipitate. A sparingly soluble sulphate has been obtained. The hydrochloride of the amino-acid also gives a sulphur derivative. ... 

For the sulphur derivative, the most recent value reported is provided here [54]. At low temperature, all species appear rigid on the NMR timescale and display NMR spectra which are in agreement with the solid state structure. At higher temperatures, they appear fluxional. This is clearly shown for [RhioP(CO)22] - The P NMR spectrum in tetrahydrofuran reveals a triplet of nonets at — 80°C and an undecet at +76°C in sulpholane solution. 

Essential oil analyses of note this year are of Buchu leaf (some p-menthane sulphur derivatives), Hyssopus officinalis (methyl myrtenate, 2-hydroxyisopinocamphone, pinic acid, and pinonic acid), Laggera aurita (m-menth-6-en-8-ol), some Cymbopogon species (up to 89% of unusual p-menthadienols), and Trichostema lanceolatum (55% p-menthen-4-ol). There... 

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