Suffix amine

Amines. Amines are preferably named by adding the suffix -amine (and any multiplying affix) to the name of the parent radical. Examples are... 

Primary amines are named in the IUPAC system in several ways. For simple amines, the suffix -amine is added to the name of the alkyl substituent. You might also recall from Chapter 15 that phenylamine, C6HSNH2, has the common name aniline. 

Alternatively, the suffix -amine can be used in place of the final -e in the name of the parent compound. 

Amines are organic derivatives of ammonia. They are named in the IUPAC system either by adding the suffix -amine to the name of the alkyl substituent or by considering the amino group as a substituent on a more complex parent molecule. 

It is also common and correct to name amines with each alkyl branch listed as an attachment before the suffix -amine. In this system of nomenclature, the molecules in Figure 1.16 are ethylamine, methyl ethyl amine, and methyl diethyl amine. Several other methods of naming amines exist, but they will not be covered in this course. 

The common names of primary amines consist of the name of the alkyl branch followed by the name amine. The systematic (lUPAC) name of primary amines consists of the name of the alkane with the -e replaced by the suffix -amine. Some examples of primary amines appear in Figure 13-1. If more than one amine group is present, you need to use the appropriate prefix. 

In the names of amines, the general use of suffixes and prefixes is not always observed. Normally, the suffix -amine would be added to the name of the parent hydride and engender names such as methanamine (CH3-NH2). Further substitution on the nitrogen atom would then be indicated by prefixes, leading to names that appear very cumbersome, such as A -methylmethanamine for (CH3)2NH and N,N-dimethylmethanamine for (CH3)3N. The traditional names of methylamine, di-methylamine and trimethylamine are much simpler. In these names, the term amine is not a suffix. It is, in fact, the name of the parent hydride, NH3, which now serves as the basis of substitutive names. Names such as diethylamine and tributylamine are representative of the preferred nomenclature. Diamines are named accordingly, as with ethane-1,2-diamine for H2N-CH2-CH2-NH2 and propane-1,3-diamine for H2N-[CH2]3-NH2. There are allowed alternatives for these last two compounds ethylenediamine and propane-1,3-diyldiamine. 

Amines are named by adding the suffix-amine to the name of (a) the alkyl group attached to N or b) the longest alkane chain. The terminal e in the name of the parent alkane is dropped when amine follows but not when, for example, diamine follows [see Problem 18.1(d)]. Thus, CH3CH(NH2)CHjCHj is named sec-butylamine or 2-butanamine. Amines, especially with other functional groups, are named by considering amino, N-alkylamino and N,N-dialkylamino as substituents on the parent molecule N indicates substitution on nitrogen. 

Amines are organic derivatives of ammonia in the same way that alcohols and ethers are organic derivatives of water. That is, one or more of the ammonia hydrogens is replaced in amines by an organic substituent. As the following examples indicate, the suffix -amine is used in naming these compounds ... 

For more complex amines, systematic nomenclature is employed. Such names are constructed in a manner very similar to that employed to name alcohols. The largest chain attached to the nitrogen is chosen as the root, numbered so that the carbon attached to the nitrogen has the lower number, and the suffix -amine is attached. Other groups that are attached to the nitrogen are given the prefix N-. 

Common names of amines are formed from the names of the alkyl groups bonded to nitrogen, followed by the suffix -amine. The prefixes di-, tri-, and tetra- are used to describe two, three, or four identical substituents. 

Amines arc uranic ilerivaUves of ammonin. Th y are nanved itt the lUPAC system either by addiitR the suffix -amine to t e names of the alkyl sub-9titu nl9 or by coiuiidering th anuiio group as asubstiluent on a more com plox parent molecule. 

When naming amines, the —NH2 (amino) group is indicated by the suffix -amine. When necessary, the position of the amino group is designated by a number. If more than one amino group is present, the prefixes di-, tri-, tetra-, and so on are used to indicate the number of groups. 

Named by specifying the groups attached to the nitrogen atom (N) alphabetically, followed by the suffix amine... 

Amines prefix amino- suffix -amine—substituents on nitrogen denoted by "AT ... 

The radical formed by detachment from the anomeric hydroxyl group is indicated by replacing the final letter e by yl as in bromide 4.21 or dipotassium phosphate 4.22 of tetra-O-acetyl-a-D-glucopyranosyl. In the case of a replacement by an amino group, the suffix amine is added, as in 2-acetamido-2-deoxy-j3-D-glucopyranosylamine 4.23. 

For primary amines, where the amine is not the principal characteristic group, the the prefix amino-" is used. For example 4-aminobenzoic acid where the carboxylic acid is the principal characteristic. Otherwise, the suffix -amine is used with with either the parent hybride orthe R group substituent name. Example ethanamine or ethylamine. Alternatively, the suffix -azane can be appended to the R group substituent name Example propylazane. 

Common nomenclature of simple amines involves presenting the name of the alkyl group followed by the word amine (such as propylamine) this type of nomenclature is acceptable in IUPAC for simple amines. In IUPAC nomenclature, the name is based on the longest continuous chain of carbon atoms followed by the suffix -amine (such as 1-propanamine). Substituents on the carbon chain are located by a number substituents on the nitrogen are located with N (such as N-methyl-1-propanamine). The simplest aromatic amine is aniline. 

The nomenclature system that has gained great popularity is known as the Chemical Abstracts or CA system. This system has been approved for use by I.U.P.A.C. and will be presented here because it is logical and easy to use. In the CA system the final -e of the name of the parent compound is dropped, and the suffix -amine is added. Eor instance,... 

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