Ethyl methyl amine

H N CbHs 1. HCHO/H20/Na[H3B-CN]/ Benzyl-ethyl-methyl-amin 85 4... 

Preparation of the complex. The solution of bis[2-(hydroseleno)ethyl]methyl-amine prepared above is gradually added to a solution of nickel acetate tetrahydrate (4.32 g, 17.4 mmole) in ethanol (100 mL) and stirred for 1 h. The solvent is removed under reduced pressure to obtain a dark mass, which is extracted with benzene (10 x 80 mL). These green extracts are combined, and the benzene is removed under vacuum. The resulting solid is washed with 10 mL of methanol and 50 mL of ether and dried in vacuo to obtain the desired product. Yield = 2.01 g (38.2%). 

Phenyltrimethylolmethylamine. See Anilino-trimethylolmethane A441-L N-Phenyl-(rris-hydroxym ethyl)-methyl amine. 

C5 H13 N 02 bis-(2-hydroxy-ethyl)-methyl-amine 105-59-9 RI Temp/C Lambda/nm Ref. 

The amines are a group of compounds with the general formula R-NHj, and all the common amines are hazardous. As a class the amines pose more than one hazard, being flammable, toxic, and, in some cases, corrosive. The amines are an analogous series of compounds and follow the naming pattern of the alkyl halides and the alcohols that is, the simplest amine is methyl amine, with the molecular formula of CH NHj. Methyl amine is a colorless gas with an ammonia-like odor and an ignition temperature of 806°F. It is a tissue irritant and toxic, and it is used as an intermediate in the manufacture of many chemicals. Ethyl amine is next in the series, followed by propyl amine, isopropyl amine, butyl amine and its isomers, and so on. 

Trinitro-N-methylaniline (N-methyl picra-mide), yellow needles from EtOH contg acid, mp /l4.8° (Refs 4 7) the UV spectrum has a peak at 340 and a shoulder at 410—20m (Ref 19) CA Registry No 1022-07-7. It is prepd by the hydrolysis of the N nitroso compd (see below) at 70—80° (Ref 5) by the action of coned sulfuric acid (Ref 8) or UV light (Ref 12) on Tetryl by the action of methyl amine on Ethyl Picrate (Ref 18) or Tetryl (Ref 7) or by the action of nitric acid (d 1.42g/cc) at 0° on N,N-dimethylaniline (Ref 10). It is present in crude Tetryl and is the active der-matitic agent in the latter (Ref 12). It can be isolated from crude Tetryl and identified by thin layer chromatography (Ref 21)... 

Compound 874, as a representative of derivatives with an electron-withdrawing substituent at C-[1 of the vinyl group, is easily prepared by elimination of one benzotriazole from 2,2-/fo(benzotriazol-l-yl)ethyl methyl ketone 873. The stereoselective elimination catalyzed by NaOH gives exclusively the (E) isomer of derivative 874. Addition of nucleophiles to the double bond of vinyl ketone 874 followed by elimination of benzotriazole leads to a,P unsaturated ketones 875. Amines used as nucleophiles do not need any catalysis, but reactions with carbon and sulfur nucleophiles require addition of a base. The total effect is nucleophilic substitution of the benzotriazolyl group at the i-carbon of orji-iinsaturatcd ketone (Scheme 142) <1996SC3773>. 

The mechanism of H02 formation from peroxyl radicals of primary and secondary amines is clear (see the kinetic scheme). The problem of H02 formation in oxidized tertiary amines is not yet solved. The analysis of peroxides formed during amine oxidation using catalase, Ti(TV) and by water extraction gave controversial results [17], The formed hydroperoxide appeared to be labile and is hydrolyzed with H202 formation. The analysis of hydroperoxides formed in co-oxidation of cumene and 2-propaneamine, 7V-bis(ethyl methyl) showed the formation of two peroxides, namely H202 and (Me2CH)2NC(OOH)Me2 [16]. There is no doubt that the two peroxyl radicals are acting H02 and a-aminoalkylperoxyl. The difficulty is to find experimentally the real proportion between them in oxidized amine and to clarify the way of hydroperoxyl radical formation. 

Many LFe "(/u-0)(//-02CR)2Fe" L complexes have terdentate, triazamacrocyclic, or triazatri-podal ligands L. Examples include species with L = HB(pz)3, R = Me with L = tacn, R = Me with L = bis(2-benzimidazolylmethyl)amine, R = Me, Ph with L = A, A -bis(2-ethyl-5-methylimidazol-4-ylmethyl)aminopropane (213X R = Ph with L= Af-alkyl-Af,Af-bis(2-pyridyl-methyl)amine, alkyl = Me, Bz, adamantyl for R = Ph, also several other R for alkyl = Me and with L = bis((l-methylimidazol-2-yl)methyl)amine (214), R = Ph. In this last case hydrogen-bonding between lattice water and -oxo in the hydrated form results in a significant decrease in... 

Alkanes (C13-C58) RtDCi26 Alkanes (C15-C39) Lf 0.033DC 22 Amine, ethyl-methyl Rt 7 - l99 Ammonia-lyase R1DC194 Amylase Call Tiss ... 

Operation of path a leads to formaldehyde and ethyl amine while operation of path b leads to methyl amine and aminoacetone. Since no... 

Benzyl-methyl-amtn Methyl- (2-phenyl-ethyl) -amin Cyclohexyl-methyl-amin Hexyl-methyl-amin... 

Man erhalt auf diese Weise z. B. Benzyl-ethyl-methyl-umin (R1 = CH2—C6H5 R2 = C2H5) in 65% Ausbeute sowie 1-Dime thy lamino-dodecan (R1 = C12H2S R2 = CII3) und Benzyl-butyl-methyl-amin (R1 = CH2-C6HS R2 = C4H,) in ahnlichen Ausbeuten. 

CHj)i—C6H5 c2h5 CjH, C2H5 Methyl-(2-phenyl-ethyl) -propyl-amin 45... 

The chemical imidization of poly(amic alkyl esters) was only reported very recently [59], although reports in the literature claim chemical imidization with a traditional acetic anhydride/pyridine mixture [87]. The chemical imidization of poly(amic alkyl esters) is based on the observation that PMDA/ODA based poly(amic ethyl ester) samples, when formulated at low concentrations for size exclusion chromatography, precipitated upon standing overnight [88]. Distillation of the NMP from phosphorus pentoxide to remove low levels of methyl-amine, a known impurity in this particular solvent, eliminated this unusual behavior. The precipitated polymer had significant levels of imidization as evidenced by IR. Apparently, organic bases, such as alkyl amines, were able to catalyze the conversion of amic alkyl esters to the corresponding imide. 

Synthesis (Eisleb (I.G. Farben), 1937, Eisleb (Winthrop), 1939, Smissman and Hite, 1959 Kleemann et al. 1999) the original synthesis involved condensation of benzyl cyanide with A/,A/-bis(2-chloro-ethyl)-A/-methyl-amine, which is a skin irritant and a carcinogen. 

Exercise 23-39 Show how one could synthesize and resolve the oxide from N-ethyl-/ /-methyl-2-propenamine with the knowledge that amine oxides are somewhat basic substances having Kb values of about 10 11 (Ka 1Cr3). 

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