Structured Clinical Interview for

First MB, Spitzer RL, Gibbon M, et al Structured Clinical Interview for DSM-IV Axis I Disorders, Research Version, Patient Edition With Psychotic Screen (SCID-I/ P W/ PSY SCREEN) New York, New York State Psychiatric Institute, Biometrics Research, 1997... 

First, M. B., Spitzer, R. L., Gibbon, M., St Williams, J. B. (1994). Structured clinical interview for DSM-1V-patient edition. (SCID-I/P, Version 2.0). New York Biometrics Research Department. 

The most commonly used semi-structured diagnostic scale is the Structured Clinical Interview for DSM-IV Axis I Disorders (SCI I) First et al., 1997). A clinical version of the SCID (SCID-CV) is designed for use in clinical settings and covers the most commonly seen diagnoses according to DSM-IV. The research version of the SCID includes ratings for different subtypes, severity and course specifiers of mental disorders. The SCLD-CV contains six modules (A) Mood Episodes (B) Psychotic Symptoms (C) Psychotic Disorders (D) Mood Disorders (E) Substance Use Disorders fF) Anxiety and Other Disorders. 

First, MJT, Spitzer, R.L., Gibbon, M., Williams, J.B.W. Structured Clinical Interview for DSM-IY Axis I Disorders. American Psychiatric Press, Washington. DC, 1997. 

In the United States, the Research Diagnostic Criteria (RDC) (19) and the DSM-IV (8) both provide clear inclusion and exclusion criteria for a current episode ( Table 9-2). Evaluation of past episodes can be made using the Schedule for Affective Disorders and Schizophrenia—Lifetime Version (SADS-L) ( 20) or the Structured clinical Interview for DSM (21). In other countries, the Present State Exam (PSE) (22) can reliably distinguish mania from other disorders. Table 9-3 reviews the various clinical presentations of primary bipolar disorder and their related DSM-IV diagnoses ( 23) (see also Appendix A, Appendix G, and Appendix H). 

Spitzer RL, Williams JBW, Gibbon M, et al. The Structured Clinical Interview for DSM-lll-R. I history, rationale and description. Arch Gen Psychiatry 1992 49 624-629. 

The occurrence of psychiatric disorders has been prospectively investigated in 63 patients who received a 6-month course of interferon alfa (9 MU/week) for hepatitis C (379). All were assessed at baseline with the Structured Clinical Interview for DSM-III-R (SCID) and monitored monthly with the Hopkins Symptoms Checklist (SCL-90). Most had a history of alcohol or polysubstance dependence, and 12 had a lifetime diagnosis of major depression. There were no significant changes in the SCL-90 scores during the 6-month period of survey in the 49 patients who completed the study, even in those who had a lifetime history of major depression. At 6 months, there was probable minor depression in eight patients and major depression in one none had attempted suicide. 

The Mini-International Neuropsychiatric Interview (MINI) is a short structured diagnostic interview for DSM-IV and ICD-10 psychiatric disorders. With an administration time of approximately 15 min, it was designed to meet the need for a short but accurate structured psychiatric interview for multicenter clinical trials and epidemiology studies, and to be used as a first step in outcome tracking in non-research clinical settings (Sheehan et al.y 1998). 

Both the DSM-IV (American Psychiatric Association, 1994) and the ICD-10 (World Health Organization, 1993) are used in Japan, with the latter being the official system used to record diseases and the former preferred in research, including for clinical studies on psychotropics. No Japanese version of a structured or semistructured interview scheme based on either the DSM or ICD system for children is yet available. 

These are instruments developed to identify specific psychiatric disorders. Most of these scales are based on a structured or semi-structured interview lasting some 60 90 min. Structured interviews contain a mix of open-ended and closed questions. Open-ended questions are essential for the validity of a diagnostic procedure closed questions support the reliability and the standardization of diagnostic tools. The primary goal for the use of diagnostic scales is to reduce the variance within samples caused by diagnostic differences, i.e. to create homogeneous patient populations included in clinical trials. 

Rosen and colleagues (48) administered a structured interview, based on the Schedule for Affective Disorders and Schizophrenia (SADS) to 89 bipolar I patients, to compare psychotic and nonpsychotic manic patients on a number of clinical outcome and demographic variables (i.e., age, age at first treatment, and duration of illness). Overall, the psychotic manic group had a significantly poorer outcome in terms of social functioning. 

Alzheimer s Disease Assessment Scale (ADAS) Structured interview 21 items total 11 items in the cognitive (COG) subset. 10 items in the noncognitive behavioral subset. Each subset may be scored separately from the total ADAS score Takes 45 minutes to administer the ADAS and 35 minutes for the ADAS-COG. The ADAS-COG refers to the cognitive assessment subset commonly used to measure cognitive function in clinical drug trials. Requires training for administration and scoring... 

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