Stress ginseng

Luo, Y.M., Cheng, X.J., and Yuan, W.X., Effects of ginseng root saponins and ginsenoside Rbl on immunity in cold water swim stress mice and rats, Zhongguo Yao Li Xue Bao, 14, 401, 1993. 

Kim, D.-H., Jung, J.-S., Moon, Y.-S., Sung, J.-H., Suh, H.-W., Kim, Y.-H., and Song, D.-K. (2003a). Inhibition of intracerebroventricular injection stress induced plasma corticosterone levels by intracerebroventricularly administered compound K, a ginseng saponin metabolite, in mice. Biol. Pharm. Bull. 26,1035-1038. 

Neuroendocrine and stress effects Ginseng activates the hypothalamopituitaiy-adrenal axis. 

Majonoside-R2, a saponin found in Vietnamese ginseng restores the deficit in pentobarbital sleep caused by the stress of social isolation (Nguyen et al. 1997). This effect appears to be mediated by the neurosteroid receptor on the GABAA receptor. 

Nguyen TT, Matsumoto K, Yamasaki K, Nguyen MD, Nguyen TN, Watanabe H. (1995). Crude saponin extracted from Vietnamese ginseng and its major constituent majonoside-R2 attenuate the psychological stress- and foot-shock stress-induced anti nociception in mice. Pharmacol Biochem Behav. 52(2) 427-32. 

St John s wort and Ginseng are also frequently suggested for treating mild depression. According to syndrome differentiation in TCM, they are only suitable for treating patients who suffer from depression due to deficiency of Qi and Yang. If the patients have a Yin deficiency, internal heat or constrained heat due to stress and anxiety, these herbs may lead to restlessness and insomnia, and may make the condition worse. In this case, a Chinese herbal formula based on syndrome differentiation is more effective than that of using only these herbs. 

ABSTRACT Panax ginseng is one of the most investigated medicinal plants. In the Eastern world it has been used for more than 2000 years as a tonic and prophylactic to increase nonspecific resistance against a variety of stress agents. The plant contains more than 200 identified chemical compounds and among them the ginsenosides are considered the most important constituents. Consistent efficacy and safety require constantly uniform composition, a condition which the raw material (roots) can scarcely fulfill. 

Kaneko H, Nakanishi K. Proof of the mysterious efficacy of ginseng basic and clinical trials clinical effects of medical ginseng, Korean red ginseng specifically, its anti-stress action for prevention of disease. J Pharmacol Sci. 2004 95 158-162. 

Eleutherococcus ginseng is not used traditionally in the U.K., although it has been used for many years in the former Soviet Union. Similar to Pan ax ginseng, E. ginseng is claimed to be an adaptogen in that it increases the body s resistance to stress increases general vitality. 

He had spoken to you a few months ago about the fatigue and thought that it may be due to stress or poor diet, as he had been working very long hours to complete a contract on time. He bought some multivitamins with ginseng, but his tiredness did not improve except when he had a few days holiday. 

Awang DVC. The anti-stress potential of North American ginseng. J Herbs Spices Med Plants 1998 6 87-91. 

Fulder S. Ginseng and the hypothalamic-pituitary control of stress. Am J Chin Med 1981 9 112-118. 

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