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Stimuli-responsive drug delivery systems

Lopes, J.R., Santos, G., Barata, R, Oliveira, R., Lopes, C.M., 2013. Rhysical and chemical stimuli-responsive drug delivery systems targeted delivery and main routes of administration. Curr. Pharm. Des. 19 (41), 7169-7184. [Pg.120]

Bajpai, A., Shukla, S., Saini, R. and Tiwari, A. (eds.) (2010) Temperature sensitive release systems. In Stimuli Responsive Drug Delivery Systems From Introduction to Application UK, Smithers Rapra Technologies. [Pg.8]

Vallet-Regi, M., Manzano, M., and Colilla, M. (2013) Stimuli-responsive drug delivery systems based on mesoporous silica, in Biomedical Applications of Mesoporous Ceramics, CRC Press, New York, pp. 105-134. [Pg.1333]

Ultrasound is an important local stimulus for triggering drug release at the target tissue. Ultrasound-responsive drug delivery systems have become an important research focus in targeted therapy. [Pg.793]

Soppimath KS, Aminabhavi TM, Dave AM, Kumbar SG, Rudzinski WE. Stimulus-responsive smart hydrogels as novel drug delivery systems. Drug Dev Ind Pharm 2002 28 957-974. [Pg.181]

Stimulus-responsiveness of the membrane is a specific property that is important in drug delivery systems in the presence of stimuli [e.g. the acidic environment of a tumor) the membrane is disrupted or changes its architecture e.g. from vesicle to micelle). Responsiveness of hydrophobic blocks can be chemically achieved for various stimuli, such as pH, redox conditions, enzyme-degradation, light, temperature, and changes in a magnetic field. ... [Pg.244]

Figure 8.4 Various stimulus responsible for drug release from smart polymeric drug delivery systems with responsive material. Figure 8.4 Various stimulus responsible for drug release from smart polymeric drug delivery systems with responsive material.
If the liposomes in question are treated with the polymer after their formation, the polymer binds only to the outer surface of the liposomes. If the liposomes are formed from a lipid-polymer mixture, on the other hand, the polymer is present on both sides of the liposome membrane. Such liposomes respond even faster to temperature changes. The change of the liposome surface properties caused by the phase transition of stimulus-responsive polymers in also known to affect their interaction with cells. The phenomenon has been used in an attempt to develop a targeted drug delivery system. Liposomes modified with a pH-sensitive polymer, namely succinylated poly(glycidol), were shown to deliver the dye cacein more efficiently into cultured monkey kidney cells than nonmodified liposomes. ... [Pg.129]

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See also in sourсe #XX -- [ Pg.2031 , Pg.2033 ]



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Drug delivery stimuli-responsive

Responsibilities Systems

Responsive delivery systems

Responsive drug delivery

Responsive systems

Stimuli-responsive systems

Stimulus

Stimulus-response

System response

System responsiveness

Systemic response

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