Stent angioplasty

Malek AM, Higashida RT, Phatouros CC, Lempert TE, Meyers PM, Smith WS, Dowd CP, Halbach VV. Endovascular management of extracranial carotid artery dissection achieved using stent angioplasty. AJNR Am J Neuroradiol 2000 21 ... 

Fig. 9.4 Proliferative vessel wall response 4 weeks after stent angioplasty in three coronary arteries from the same hypercholesterolemic minipig infused with vehicle, activator protein-l (AP-l) con-...

Fig. 40.12. Symptomatic high-grade stenosis of the middle cerebral artery. Stent angioplasty, DSA, 3D-DSA, and FD-3D-DSA. Result of angioplasty, native FD-CT showing the stent...

GPIIb/IIIa antagonists have to be administered parenterally. They are currently used prophylactically during intracoronary interventions such as percutaneous transluminal revascularization with balloon angioplasty or intracoronary stenting, as well as to treat acute coronary syndromes like unstable angina and acute myocardial infarction. The main complications... 

Percutaneous coronary intervention (PCI) is one of a host of techniques performed by using a catheter inserted via a major limb artery that aims to relieve nanowing of coronary arteries. For example, percutaneous transluminal coronary angioplasty (PTCA) is the classic PCI that uses a catheter-directed balloon to dilate a stenotic coronary artery, and more recent PCIs include stent implantation, rotational atherectomy, and laser angioplasty. 

Lylyk R Cohen JE, Ceratto R, Eerrario A, Miranda C. Angioplasty and stent placement in intracranial atherosclerotic stenoses and dissections. AJNR Am J Neuroradiol 2002 23 430 36. 

Carotid angioplasty with or without stenting is typically restricted to patients who are refractory to medical therapy and are not surgical candidates. Clinical trials are currently ongoing to further define the role of carotid angioplasty in both symptomatic and asymptomatic patients. 

Coronary interventions (coronary bypass, percutaneous transluminal coronary angioplasty, or stents)... 

Initial tests in the rat revealed a high degree of tissue compatibility of Dat-Tyr-Hex derived polymers. More detailed tests are now in progress. In addition, tyrosine derived polymers are currently being evaluated in the formulation of an intracranial controlled release device for the release of dopamine, in the design of an intraarterial stent (to prevent the restenosis of coronary arteries after balloon angioplasty), and in the development of orthopedic implants. The use of tyrosine derived polymers in these applications will provide additional data on the biocompatibility of these polymers. 

Cardiac catheterization and coronary angiography are used in patients with suspected CAD to document the presence and severity of disease as well as for prognostic purposes. Interventional catheterization is used for thrombolytic therapy in patients with acute MI and for managing patients with significant CAD to relieve obstruction through percutaneous transluminal coronary angioplasty, atherectomy, laser treatment, or stent placement. 

Angioplasty may take between 30 minutes to 3 hours to complete. It begins with a distinctive dye that is injected into the bloodstream. A thin catheter is then inserted into the femoral artery of the leg, near the groin. The doctor monitors the path of the dye using x-rays. He moves the tube through the heart and into the plaque-filled artery. He inflates the balloon, creating more space, deflates the balloon, and removes the tube. It is important to note that the plaque has not been removed it has just been compressed against the sides of the artery. Sometimes, a stent may be implanted, a tiny tube of stainless steel that is expandable when necessary. Its function is to keep the artery open. 

Betriu A, Masotti M, Serra A, et al. Randomized comparison of coronary stent implantation and balloon angioplasty in the treatment of de novo coronary artery lesions (START) a four-year follow-up. J Am Coll Cardiol 1999 34 1498-1506. 

Inoue T, Sohma R, Miyazaki T, Iwasaki Y, Yaguchi I, Morooka S. Comparison of activation process of platelets and neutrophils after coronary stent implantation versus balloon angioplasty for stable angina pectoris. Am J Cardiol 2000 86 1057-1062. 

Kollum M, Kaiser S, Kinscherf R, Metz J, Kubler W, Hehrlein C. Apoptosis after stent implantation compared with balloon angioplasty in rabbits. Role of macrophages. Arterioscler Thromb Vase Biol 1997 17 2383-2388. 

Feldman LJ, Mazighi M, Scheuble A, et al. Differential expression of matrix metalloproteinases after stent implantation and balloon angioplasty in the hypercholesterolemic rabbit. Circulation 2001 103 3117-3122. 

Feldman LJ, Aguirre L, Ziol M, et al. Interleukin-10 inhibits intimal hyperplasia after angioplasty or stent implantation in hypercholesterolemic rabbits. Circulation 2000 101 908-916. 

Rogers C, Edelman ER, Simon DI. A mAb to the beta2-leukocyte integrin Mac-1 (CDllb/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits. Proc Natl Acad Sci USA 1998 95 10134—10139. 

Zotarolimus (53 Endeavor stent) Sirolimus (33) Macrolide antibiotic Semi-synthetic NP Microbial Cardiovascular surgery Inhibits cell proliferation, preventing scar tissue formation and minimizes restenosis in angioplasty patients 467 74... 

Modern Angioplasty and Stent Technology Technique, Application and Efficacy, Comparison to Surgical... 

Serruys PW, de Jaegere P, Kiemeneij F, et al., for the BENESTENT study group. A comparison of balloon-expandable stent implantation with balloon angioplasty in patients with coronary artery disease. N Engl J Med 1994 331 489 95. 

Rodriguez A, Bernardi V, Navia J, et al. Argentine randomized study coronary angioplasty wih stenting versus coronary artery bypass surgery in patients with multiple vessel disease 30-day and one year follow-up results. J Am Coll Cardiol 2001 37 51-58. 

Rodriguez A, Baldi J, Pereira C, et al. Five-year followup of the argentine randomized trial of coronary angioplasty with stenting versus coronary bypass surgery in patients with multiple vessel disease. J Am Coll Cardiol 2005 46 583-588. 

Grines CL, Cox DA, Stone GW, et al. Coronary angioplasty with or without stent implantation for acute myocardial infarction. N Engl J Med 1999 341 1949-1956. 

Maillard L, Hamon M, Khalife K, et al. A comparison of systematic stenting and conventional balloon angioplasty during primary percutaneous transluminal coronary angioplasty for acute myocardial infarction. J Am Coll Cardiol 2000 35 1729-1736. 

Antoniucci D, Santoro GM, Bolognese L, et al. A chn-ical trial comparing primary stenting of the infarct related artery with optimal primary angioplasty for acute myocardial infarction (FRESCO). J Am Coll Cardiol 1998 31 1234-1239. 

---