Scars prevention

The treatment goals for acne vulgaris are to eliminate existing lesions and prevent new lesions from developing, as well as to decrease discomfort and the incidence of scarring. 

The goals of treatment are to prevent the formation of new acne lesions, heal existing lesions, and prevent or minimize scarring. 

Zotarolimus (53 Endeavor stent) Sirolimus (33) Macrolide antibiotic Semi-synthetic NP Microbial Cardiovascular surgery Inhibits cell proliferation, preventing scar tissue formation and minimizes restenosis in angioplasty patients 467 74... 

Targeting of anti-inflammatory and anti-fibrotic drugs to the proximal tubular cell may prevent tubulointerstitial inflammation and scarring secondary to systemic and glomerular infection and proteinuria. Furthermore, tubular drug dehvery may be beneficial during shock, renal transplantation, ureter obstruction, diabetes, proteinuria, renal carcinoma and some tubular defect diseases such as Fanconi and Bartter s s5mdrome. 

Eventually, Buscher experimented on human volunteers. Like Cullumbine, he found that, when a drop of H is placed on skin, the initial reaction appears in about 2 h. Vesication begins in about 24 h, but healing does not begin until after about 4 wk, and later for severe burns. Buscher wrote "There are also irreparable, permanent injuries.. . . Cicatricial contractures are very frequent sequelae.. . . Following severe wounds this scarring is very extensive so that there can be no question of complete recovery." In all cases of extensive burns from mustard gas, careful and extended treatment is required to prevent infection and other complications. 

In the eighteenth century, Louis Laurent Heister (1683-1758) wrote a chapter about the study of bums in his Institutions de chirurgie. He describes four grades of bums and prescribes the use of local treatments. He advises surgeons to look after the healing to prevent vicious scars. 

V. The adhesion joint should not prevent (ideally it should contribute to) the formation of connective tissue scars and regeneration of the tissues. 

The presence of an implant almost always energizes the body s immune system, which sends out white hlood cells to destroy the "foreign invader" (the implant). Even if a hiocompatihle material is used for the implant, inflammation caused hy the surgical procedure used in its insertion may also cause an immune response. Although the immune system s macrophages are generally unable to eliminate the implant itself, they may cause scar tissue to form around the implant. The scar tissue often prevents the restoration of normal tissue at the site of the implant, which can prompt an early failure of the implant itself. 

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