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Starch disintegrating agents, tablets

A comparative study of chitin obtained from lobsters, starch, and carboxymethyl chitosan as disintegrating agents was conducted. The influence of the method in the preparation of tablets on the disintegrating activity of both polymers was evaluated. Chitin proved to have good characteristics as a disintegrating agent independently... [Pg.1002]

Starch Also acts as disintegrating agent, may give soft tablets... [Pg.3656]

For many years, starch was the disintegrating agent of choice. Recently, however, so-called super disinte-grants have been introduced, which markedly reduce tablet disintegration time. Such substances include croscarmellose, crospovidone, polacrilin potassium, and sodium starch glycolate. ... [Pg.3661]

The mechanism of action of disintegrating agents has been the subject of some debate. Some substances such as starch swell when they come into contact with water, and disruption of the tablet structure has been attributed to this. However, other effective disintegrants do not swell in this way, and are believed to act by providing a network of hydrophilic pathways inside the tablet through which water can diffuse. Irrespective of the precise mechanism of disintegration, it is clear that water uptake into the tablet must be the first step in the disintegration process. ... [Pg.3661]

Patel NR, Hopponen RE. Mechanism of action of starch as a disintegrating agent in aspirin tablets./ Pharm Sci 1966 55 1065-1068. [Pg.730]

In the case that the same ingredient may serve more than one function, this must be stated (e.g., starch in a tablet may be a binding agent, disintegrant and or filler). [Pg.652]

The concentration and the type of disintegrating agent used in a tablet dosage form can greatly influence the dissolution and bioavailability of a therapeutic agent. The dissolution rate is usually increased when the concentration of starch is increased in a tablet formulation. The effect of... [Pg.176]

Carrageenin Suspending agent Pregelatinized starch Tablet disintegrant... [Pg.406]

In recent times, modified starches especially sodium carboxymethylated derivative, commercially known as sodium starch glycolate (SSG), and pregelatinized starches have been evaluated as super disintegrant (i.e., agent for dispersing the solid drug within a few minutes or making a dispersible tablet). Further, many researchers have explored various other starch sources for sodium carboxymethyl derivative of starch, which is officially known as SSG. ... [Pg.577]

See other pages where Starch disintegrating agents, tablets is mentioned: [Pg.230]    [Pg.113]    [Pg.684]    [Pg.269]    [Pg.7]    [Pg.1264]    [Pg.984]    [Pg.3480]    [Pg.3553]    [Pg.3564]    [Pg.3647]    [Pg.3648]    [Pg.3673]    [Pg.3681]    [Pg.74]    [Pg.115]    [Pg.57]    [Pg.58]    [Pg.69]    [Pg.69]    [Pg.478]    [Pg.479]    [Pg.492]    [Pg.2468]    [Pg.242]    [Pg.148]    [Pg.415]    [Pg.1110]    [Pg.3480]    [Pg.260]    [Pg.95]    [Pg.1134]    [Pg.1418]    [Pg.3]    [Pg.3]    [Pg.4709]    [Pg.14]    [Pg.174]    [Pg.141]    [Pg.2526]   
See also in sourсe #XX -- [ Pg.3661 ]



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Disintegrants

Disintegrates

Disintegrates starches

Disintegrating agents starch

Disintegrating agents tablets

Disintegration

Disintegration agents

Disintegrator

Tablet disintegrant

Tablet disintegrants

Tablet disintegration

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