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Disintegrating agents starch

Starch is often cited as a filler, but it is more commonly used in its dry state as a disintegrating agent. However, modified starches such as StaRx 1500 and National 1551 (partially hydrolyzed, or pregelatinized starch) are marketed for direct compression and appear to offer the advantage of substantial mechanical strength and rapid drug release. [Pg.299]

A comparative study of chitin obtained from lobsters, starch, and carboxymethyl chitosan as disintegrating agents was conducted. The influence of the method in the preparation of tablets on the disintegrating activity of both polymers was evaluated. Chitin proved to have good characteristics as a disintegrating agent independently... [Pg.1002]

Starch Also acts as disintegrating agent, may give soft tablets... [Pg.3656]

Starch, pregelatinized Also acts as disintegrating agent. (Lycatab , Pharma-Gel , Pre-Jel , Sepistab , Starch 1500 , Starx 1500 )... [Pg.3656]

For many years, starch was the disintegrating agent of choice. Recently, however, so-called super disinte-grants have been introduced, which markedly reduce tablet disintegration time. Such substances include croscarmellose, crospovidone, polacrilin potassium, and sodium starch glycolate. ... [Pg.3661]

The mechanism of action of disintegrating agents has been the subject of some debate. Some substances such as starch swell when they come into contact with water, and disruption of the tablet structure has been attributed to this. However, other effective disintegrants do not swell in this way, and are believed to act by providing a network of hydrophilic pathways inside the tablet through which water can diffuse. Irrespective of the precise mechanism of disintegration, it is clear that water uptake into the tablet must be the first step in the disintegration process. ... [Pg.3661]

Patel NR, Hopponen RE. Mechanism of action of starch as a disintegrating agent in aspirin tablets./ Pharm Sci 1966 55 1065-1068. [Pg.730]

Materials that act as disintegration agents with poor flow characteristics Microcrystalline cellulose Directly compressible starch Probably the most widely used direct compression excipients. Excellent compactibility at low pressures, high dilution capacity. [Pg.423]

The concentration and the type of disintegrating agent used in a tablet dosage form can greatly influence the dissolution and bioavailability of a therapeutic agent. The dissolution rate is usually increased when the concentration of starch is increased in a tablet formulation. The effect of... [Pg.176]

Impression plasters are manufactured from the finest finishing plasters, selected for color and purity. Setting time accelerators, setting expansion control agents, fillers, flavors, colors, or other special modifying agents may be added, eg, starch, to cause disintegration of the plaster impression when it is boiled. [Pg.476]

Carrageenin Suspending agent Pregelatinized starch Tablet disintegrant... [Pg.406]

Disintegrating and wetting agents agar, alginic acid, bentonite, microcrystalline cellulose, gelatin, magnesium aluminium silicate, methylcellulose, sodium lauryl sulphate, starch, and starch derivatives. [Pg.50]

See other pages where Disintegrating agents starch is mentioned: [Pg.7]    [Pg.7]    [Pg.230]    [Pg.113]    [Pg.305]    [Pg.684]    [Pg.269]    [Pg.1264]    [Pg.783]    [Pg.984]    [Pg.376]    [Pg.3480]    [Pg.3553]    [Pg.3564]    [Pg.3647]    [Pg.3648]    [Pg.3673]    [Pg.3681]    [Pg.74]    [Pg.115]    [Pg.57]    [Pg.57]    [Pg.58]    [Pg.69]    [Pg.69]    [Pg.478]    [Pg.478]    [Pg.479]    [Pg.376]    [Pg.14]    [Pg.492]    [Pg.242]    [Pg.21]    [Pg.138]    [Pg.206]    [Pg.646]    [Pg.148]    [Pg.415]   
See also in sourсe #XX -- [ Pg.3661 ]



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Disintegrates

Disintegrates starches

Disintegration

Disintegration agents

Disintegrator

Starch disintegrating agents, tablets

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