Soft tissues allografts

Lubowitz JH, Schwartzbtag R, Smith P (2015) Cortieal suspensory button versus aperture interference screw fixatiorr for knee anterira cruciate ligamcut soft-tissue allograft a prospective, randomized controlled trial. Arthroscopy 31(9) 1733-1739... 

Soon, M. Y., Hassan, A., Hui, J. H., Goh, J. C., and Lee, E. H. 2007. An analysis of soft tissue allograft anterior cruciate ligament reconstruction in a rabbit model A short-term study of the use of mesenchymal stem cells to enhance tendon osteointegration. Am. J. Sports Med. 35 962-971. 

Allografts and xenografts in soft tissue repair current use and future trends... 

There are other areas where opportunities exist to improve allograft and xenograft performance. For example, device-related infections are a costly complication in soft tissue repair procedures such as abdominal wall repair. The local delivery of antibiotics may reduce postsurgical infections. The TYRX mesh now marketed by Medtronic/ Covidien delivers antibiotics to the subcutaneous pocket following implantation of a pacing device. The incorporation of antibiotics or other antimicrobial agents such as lysostaphin, as by Stishkumar et al., may represent an innovative approach to infection control particularly in contaminated and infected wounds. 

H) Collagen derived from the same species as recipient Tissues derived from the same species, for example, tissue grafts for medical use derived from human cadaveric donors, are referred to as allografts. These tissues constitute a plentiful source of stmctural materials for use in surgical repair of the musculoskeletal system. In contrast to vital organs for transplantation that are utilized without modification, stmctural tissues such as bone and soft connective tissues must be processed to remove blood, cells, soluble proteins, and enzymes before they can be used in vivo. Allografts retain many of their intrinsic stmctural and biomechanical properties. 

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