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Sodium taurodihydrofusidate

JP Longenecker, AC Moses, JS Flier, RD Silver, MC Carey, EJ Dubovi. (1987). Effects of sodium taurodihydrofusidate on nasal absorption of insulin in sheep. J Pharm Sci 76 351-355. [Pg.385]

Deurloo, M.J., et al. 1989. Absorption enhancement of intranasally administered insulin by sodium taurodihydrofusidate (STDHF) in rabbits and rats. Pharm Res 6 853. [Pg.391]

Most compounds of interest for nasal delivery have a molecular weight in excess of 1,000 Da and until recently were thought to cross the cells endocytically. However, a recent study in rats has shown the transport of fluoroscein isothiocyanate (FITC)-labeled dextran (M. Wt. = 3,000 Da) to be via the paracellular pathway, with only a proportion moving endocytically. Hardly any transport of FITC-labeled dextran with a molecular weight of 10,000 Da was observed unless a penetration enhancer was coadministered, but the penetration enhancer, sodium taurodihydrofusidate (STDHF), caused cell swelling and extrusion of mucus. [Pg.230]

Peptide delivery It has also been reported that a polycarbophil hydrogel formulation increased the vaginal membrane permeability of GnRH, in comparison to a solution, in rats. Co-administration of the GnRH loaded gel with various enzyme inhibitors (EDTA, sodium taurodihydrofusidate and sodium laurate) resulted in ovulation-inducing activity comparable with that of a sc injection. [Pg.296]

Bile salts sodium deoxycholate sodium glycocholate sodium fusidate sodium taurodihydrofusidate denaturation of proteins decrease of mucus viscosity decrease of peptidase activity solubilization of peptides formation of reversed micelles... [Pg.15]

Steroid and steroid esters Cholate, deoxycholate, taurocholate, glycocholate, taurodeoxycholate, sodium taurodihydrofusidate, and cholesterol esters... [Pg.983]

Fusidic acid derivatives (sodium taurodihydrofusidate, sodium dihydrofusidate)... [Pg.509]

Sodium 5-methoxysalicylate 1465 Sodium caprate 1376 Sodium deoxycholate 1465 Sodium dodecyl sulfate-polyacrylamide gel electrophoresis, see SDS-PAGE Sodium glycocholate 1465 Sodium glycodeoxycholate 1376 Sodium salicylate 1376, 1466 Sodium taurodihydrofusidate 1376 Softenon 1675 Solanum lycopersicum 970 Solanum tuberosum 485 Solclot 462 Solid tumor 1174... [Pg.1880]

See other pages where Sodium taurodihydrofusidate is mentioned: [Pg.141]    [Pg.113]    [Pg.126]    [Pg.214]    [Pg.910]    [Pg.379]    [Pg.460]    [Pg.69]    [Pg.238]    [Pg.606]    [Pg.16]    [Pg.2674]    [Pg.1376]    [Pg.1472]    [Pg.399]   
See also in sourсe #XX -- [ Pg.126 ]

See also in sourсe #XX -- [ Pg.253 , Pg.262 , Pg.263 , Pg.264 ]

See also in sourсe #XX -- [ Pg.2674 ]



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