Sodium inosine

Let us now proceed to umami substances. Monosodium glutamate, di sodium inosinate and disodium guanylate exhibit umami. Umami is a Japanese term implying "deliciousness of meat, mushrooms, some vegetables and cheese, but is now acknowledged widely as the fifth taste [5], Umami substances exhibit a very interesting phenomenon, i.e., a synergistic effect. In the coexistence of MSG and IMP, we experience drastic increase in umami. 

Umami" is the Japanese word used to describe the sensation elicited by compounds such as monosodium glutamate, sodium inosinate, sodium guanylate, and ibotenic acid (26-29). The umami sensation is sometimes translated as the sensation of "delicious-ness". The possibility of more than one umami sensation exists, since the monophosphate nucleotides stimulate far back in the oral... 

DISODIUM INOSINE-5 -PHOSPHATE IMP DISODIUM SALT 5 -IMP DISODIUM SALT IMP SODIUM SALT INOSINE-5 -MONOPHOSPHATE DISODIUM INOSIN-5 -iMONOPHOSPHATE DISODIUM SODIUM INOSINATE SODIUM-5 -INOSINATE... 

SODIUM o-((3-(HYDROXYMERCURI)-2-METHOXYPROPYL)CARBAMOYL)PHENOXY ACETATE see SIH500 SODIUM HYPOCHLORITE see SHU500 SODIUM HYPOPHOSPHITE see SHVOOO SODIUM HYPOSULFITE see SKIOOO SODIUM INOSINATE see DXE500 SODIUM-5 -INOSINATE see DXE500 SODIUM IODIDE see SHWOOO SODIUM IODINE see SHWOOO SODIUM ISOAMYLETHYL BARBITURATE see AON750... 

See inosinic acid sodium inosinate. (2) Abbreviation for insoluble metaphosphate (Maddrell salt). 

CCRIS 6560 Disodium inosinate Disodium 5 -inosinate Disodium inosine 5 -monophosphate Disodium inosine 5 -phosphate EINECS 225-146-4 FEMA No. 3669 Gluxor 1626 IMP disodium salt IMP sodium salt 5 -lmp disodium salt 5 -lnosinic acid, disodium salt lnosin-5 -monophosphate disodium lnosine-5 -monophosphate disodium Inosine 5 -monophosphate disodium salt hydrate Inosine-5 -monophosphoric acid disodium salt Luxor 1639 NSC 20263 Sodium inosinate Sodium 5 -inosinate IMP sodium Disodium IMP Sodium 5-inosinate Disodium 5 -inosinate Inosine 5 -disodium phosphate. A 5 -nucleotide derived from seaweed or dried fish Flavor potentiator in foods. Solid soluble in H2O slightly soluble in alcohol insoluble in ether LDso (rat orl) = 15,900 mg/kg. Lancaster Synthesis Co. Penta Mfg. 

IMP disodium salt IMP sodium salt Inosine 5 -disodium phosphate lnosine-5 -monophosphate disodium Sodium inosinate Sodium 5 -inosinate... 

Pleasant is associated with the small fibre geniculate ganglion system and is evoked by lactones and similar carbon-oxygen compounds. Umani is a Japanese word used to describe the sensation elicited by the amino acid monosodium glutamate and the nucleotides sodium inosinate and sodium guanylate. The metallic sensation is produced by certain salts such as silver... 

Isolation of Inosine by Ion Exchange Method Half of the above clear centrifugate (1.15 liters) is treated with 250 cc of anion exchange (bicarbonate form) and stirred together therewith for 16 hours at room temperature. The pH value is increased thereby to about 4 to 5. The ion exchanger is filtered off under suction and washed 3 times, each time with 150 cc of water. The solution is brought to a pH value of 7 by means of normal sodium hydroxide (total volume of the solution about 1.55 liters), and concentrated to a volume of about 100 cc under vacuum. 

On silylation-amination of the disodium salts of inosine-5 -phosphate 238a or of guanosine-5 -phosphate 238 b with benzylamine, the phosphate moieties are also transiently protected during amination by silylation (cf also the silylation of uridine-5 -phosphate 224) to give, after transsilylation with methanol and addition of NaOH, the desired sodium salt of N -benzyladenosine-5 -phosphate 239a in 80% yield and the sodium salt of the 2-amino derivative 239 b in 78% yield [64] (Scheme 4.23). 

C23H32N10O16P2Pt2--0.4 CioHnN408P2- 2.4 Na+-13.8 HzO Sodium (trimethylenediamine)bis(inosine 5 -phosphato)platinum(II) inosine 5 -phosphate, hydrate (INOSPU)347... 

C20H28N 10O16P2Pt2- 0.88 hydrate Sodium diammine-platinum-(inosine 5 -phosphate)-inosine SINPPT 34 375... 

C10HuN4OsPs, 2.88 Na+16 HjO 0.86 C20H28N10O16P2Pt2-0.28 5 -phosphate, hexadecahydrate Sodium diammine-bis(inosine 5 -phosphate)-platinum(n)- IMPPTS 43 308... 

Mycophenolate sodium (62 Myfortic ) Mycophenolic acid (61) Fatty acid antibiotic NP Microbial Immuno- suppression Inhibits inosine monophosphate dehydrogenase (IMPDH) activity 215-217, 532-560... 

Mycophenolate sodium (62 Myfortic Norvatis, 2003) is an immunosuppressant drug used to prevent rejection in organ transplantation. It is a selective, noncompetitive, reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH), the rate-limiting enzyme in the de novo pathway of guanosine nucleotide synthesis. Thus, mycophenolic acid (61), originally... 

Mycophenolate mofetil is used together with cyclosporine and corticosteroids for the prophylaxis of acute organ rejection in patients undergoing allogeneic renal, or hepatic transplants. Compared with azathioprine it is more lymphocyte-specific and is associated with less bone marrow suppression, fewer opportunistic infections and lower incidence of acute rejection. More recently, the salt mycophenolate sodium has also been introduced. Mycophenolate mofetil is rapidly hydrolyzed to mycopheno-lic acid, its active metabolite. Mycophenolic acid is a reversible noncompetitive inhibitor of inosine monophosphate dehydrogenase, an important enzyme for the de novo synthesis of purines. As lymphocytes have little or no salvage pathway for purine... 

Adenosine 3, 5 -cyclic phosphate166 8-Bromoguanosine dihydrate167 D-Ribofuranosyl-6-thiopurine168 Inosine 5 -(sodium phosphate) octahydrate169 5-Bromo-5-deoxythymidine (form B)170... 

Mixtures of photolabile 2 - and 3 -0-(2-nitrobenzyl)ribonucleosides were obtained in good yields when adenosine, uridine, cytidine, and inosine were treated with 2-nitrophenyldiazomethane in the presence of tin(II)chloride [362]. The dibutylstan-nylene approach has been used for the preparation of 2 -(4-nitrobenzyl)uridine [366]. 2-Nitrobenzyl chloride and sodium hydride in DMF gave the 2 -ethers in 26-37% yield, depending on the starting nucleoside [363, 367]. 

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