Skin disorders discoloration

Floxuridine FUDR Carcinoma of the Gl tract and liver Gl disorders [nausea, vomiting, loss of appetite] skin disorders [discoloration, rash, hair loss]... 

Adverse Effects. The most serious problem associated with chloroquine is the possibility of toxicity to the retina and subsequent visual disturbances. This issue is usually insignificant, however, when this drug is used for short periods in relatively low doses (see Chapter 16). Other relatively mild side effects may occur, including gastrointestinal distress (nausea, vomiting, stomach cramps, diarrhea), behavior and mood changes (irritability, confusion, nervousness, depression), and skin disorders (rashes, itching, discoloration). 

Generic Name Bleomycin Trade Name Blenoxane Primary Antineoplastic Indication(s) Carcinoma of head, neck, cervical region, skin, penis, vulva, and testicle Hodgkin disease non-Hodgkin lymphomas Common Adverse Effects Pulmonary toxicity [interstitial pneumonitis] skin disorders [rash, discoloration] mucosal lesions fever Gl distress general weakness and malaise... 

The principal adverse reaction associated with warfarin is bleeding, which may range from very mild to severe. Bleeding may be seen in many areas of the body, such as the bladder, bowel, stomach, uterus, and mucous membranes. Other adverse reactions are rare but may include nausea, vomiting, alopecia (loss of hair), urticaria (severe skin rash), abdominal cramping, diarrhea, rash, hepatitis (inflammation of the liver), jaundice (yellowish discoloration of the skin and mucous membranes), and blood dyscrasias (disorders). 

Amiodarone, for example (Fig. 1.12), was introduced as a coronary dilator for angina, but concern about comeal deposits, discoloration of skin exposed to sunlight and thyroid disorders led to the withdrawal of the drug in 1967. However, in 1974 amiodarone was found to be highly effective in the treatment of a rare type of arrhythmia known as the Wolff-Parkinson-White syndrome. Accordingly, amiodarone was reintroduced specifically for that purpose [22]. 

Chlorpromazine is a phenothiazine derivative used in the treatment of various psychiatric disorders. Often, high prolonged doses of medication are required, and these have led to well-documented phototoxic changes in the cornea and lens as well as pronounced skin discoloration. It is now generally accepted that chlorpromazine is the only phenothiazine to cause such ocular changes. 

CHRONIC HEALTH RISKS paleness coated tongue stomach disorders nervousness metallic taste garlic breath numbness brittle hair excessive tooth decay and discoloration deformed nails or loss of nails discoloration of skin liver damage damage to the spleen anemia fluid in abdominal cavity lack of mental alertness listlessness paralysis skin rashes skin sensitization. 

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