Selenium effects research

Selenium Subcommittee on Selenium, Committee on Medical and Biological Effects of Environmental Pollutants, National Research Council, National Academy of Sciences, Washington, D.C., 1976, p. 51. 

Hu, M.-L., Dillard, C.J. and Tappel, A.L. (1988) Aurofhioglucose effect on sulfhydryls and glutathione-metabolizing enzymes in vivo inhibition of selenium-dependent glutathione peroxidase. Research Communications in Chemical Pathology and Pharmacology, 59,... 

Baker, M. A. and Tappel, A.L. (1986) Effect of gold thioglucose on subcellular selenium distribution in rat liver and kidney. Biological Trace Element Research, 9, 113-123. 

Additional fundamental and basic research is required on selenium metabolism, physiology, recycling, interactions with other compounds or formulations, and chemical speciation in order to elucidate its nutritive role as well as its toxic effects. 

D. Hausknecht and R. Ziskind, Health Effects of Selenium, NTIS PB-250568, Electric Power Research Institute, EPRI EA-571-V1, Palo Alto, Calif., Jan. 1976. 

Yes, it is right that selenium has some antagonistic effects on other poisoning elements, and also I can mention interference with vitamin E, so that a combination of selenium and vitamin E can give quite a good result. The fact is that we know too little about it, but in other ways this is a question for further research. 

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