Salicylic acid formula

CAS 59866-70-5 EINECS/ELINCS 261-963-2 Synonyms Benzoic acid, 2-hydroxy-, monoethanolamine salt Definition Monoethanolamine salt of salicylic acid Formula C7H6O3 C2H7NO Uses Preservative in cosmetics... 

Chemical Name 2, 4 -Difluoro4-hydroxy-[ 1,1 -biphenyl] -3<arboxylic acid Common Name Difluorophenyl salicylic acid Structural Formula cooh... 

Only four years after Kekule proposed the ring structure for benzene, and before the configuration of salicylic acid was established, Kraut concluded on the basis of sound chemical evidence that the products obtained on heating acetylsalicylic acid possess chain structures formed through intermolecular esterification. He assigned the dimeric and tetrameric formulas... 

Salicylic acid (Fig. 13.4.2) is an example of a carboxylic acid with the general formula R-COOH. In this class of organic compounds the carbonyl functionality... 

The direct reaction of [TCO4] in ethanolic solution with dppe and oxalic acid produces the red Tc" complex [Tc(ox)(dppe)2] (552). Attempts to prepare similar complexes with succinic acid, phthalic acid, or salicylic acid failed, or the complexes were stable in solution only. " Similarly, cationic complexes of Tc" are produced by reaction of the versatile precursor [TcO(OH)(dppe)2] (204) with various dithiocarbamates, which produces several complexes of general formula [Tc(dtc)(dppe)2] (553). For this reaction the reductant formamidine sulphinic acid (510) was required in an alkaline solution. The X-ray crystal structure of [Tc(S2CNMe2)(dppe)2] (554) shows a distorted octahedral geometry. Cyclic voltammetry reveals a reversible reduction wave Tc"/Tc couple at —0.53 V, and a reversible oxidation at +0.3 V for the Tc" /Tc" couple. The same compound (554) was also prepared from the thiourea precursor [TcO(tmtu)4] + (91).The reaction of this precursor in dmf in the presence of dppe produced a mixture of brown [TcO(dtc)(tmtu)2] and the Tc" complex (553). The first compound is probably an intermediate... 

The formulas of salicylic acid, salol, and acetylsalicylic acid are given below to show the structural modifications that turned an unsatisfactory product into a much better product. 

It was found that salicylic acid in its pure form had a number of defidencies, and for a number of years chemists sought a salicylic acid-based compound that would be effective yet less harsh and that could counteract pain with smaller dosages. This process ended in 1898 with the introduction by Bayer of acetylsalicylic acid, which has the formula C6H4(COOH)C02CHs and since then has been commonly referred to as aspirin, See also Acetylsalicylic Acid and Salicylic Acid and Related Compounds. 

Salicylic acid, used in the manufacture of aspirin, contains only the elements C, H, and O and has only one acidic hydrogen. When 1.00 g of salicylic acid undergoes complete combustion, 2.23 g C02 and 0.39 g H20 are obtained. When 1.00 g of salicylic acid is titrated with 0.100 M NaOH, 72.4 mL of base is needed for complete reaction. What are the empirical and molecular formulas of salicylic acid ... 

Common Name Choline salicylic acid salt Structural Formula ... 

The extraction process for making the salicin also proved long and tedious and wasteful of trees from 1.5 kg of willow bark only 30 g of salicin could be obtained.3 4 Once the formula was known for salicylic acid, a group of chemists tried to work out how to make it artificially by a less expensive and tedious process. 

These mordant-dyeing properties are found in a much higher degree in the bodies obtained by action of nitrodiazo-compounds on salicylic acid (Germ. Pat. 44170, 16 Nov., 1887). The dyestuff from metanitrodiazobenzene and salicylic acid comes into commerce as Alizarin Yellow G, and produces a fine yellow lake with chromium oxide. The pure dyestuff crystallizes from alcohol in light yellow needles. M.P. about 230°. Its constitution may be expressed by the formula —... 

Cotton-yellow is obtained by action of phosgene on two molecules of amidobenzene-azo-salicylic acid, and has the formula ... 

Calculate the volume of 0.1 N salicylic acid solution required, taking into account the water content, w of the product to be tested, with the following formula ... 

Calculate the complexed salicylic acid with the following formula ... 

Karp s three formulas are well known the first was almost 80% glycerinated phenol, the second combined phenol with acetic acid, boric acid, salicylic acid and citric acid, but could only be applied locally, as it was too strong. Karp called his third formula the phoenix it was an aqueous solution of glycerinated phenol combined with acetic acid and sodium salicylate. 

Salicylic acid possesses the properties of a phenol and an acid. It gives a violet coloration with ferric chloride, a precipitate with bromine-water (C6H2Br3.0Br), and salts with bases. It forms ethers and esters such as those of the formulas—... 

Write the graphic formulas of the compounds that you would expect to be formed when (a) 0-NO2C6H4NH2 is nitrated, (6) P-NO2C6N4NH2 is brominated, (c) 0-CH3C6H4NH2 is sulphonated, (d) o-C6H4(N02)2 is bromin-ated, (e) salicylic acid is brominated. 

There is no question but that Couper was a gifted chemist, in both the experimental and the theoretical realms. In his salicylic acid paper, he reported the synthesis of salicyl trichlorophosphate, for whose formula he suggested another ring structure within the molecule— not, however, in the aromatic nucleus, but in the carboxyl/phosphate portion of the molecule. Several chemists, including Kekule, tried to reproduce this experimental result, without success. And yet Couper s experiment was indeed correct, as Kekule s student Richard Anschutz demonstrated in 1885 one simply had to follow to the letter Couper s prescriptions as to reaction conditions. By this time Couper had fallen into utter obscurity no reference work carried his name, and no one knew even so much as his nationality. 

The Stock in trade of structure theory was explaining otherwise mysterious cases of isomerism. In the first fascicle of his textbook (1859), Kekul6 offered a structural explanation for one case of aromatic isomerism, namely, benzoic acid and salicylous acid. In Kekulean terms the two substances were "metamers," or what we now call ordinary structural isomers. But subtler sorts of isomerisms were showing up in the aromatic realm. Even before structure theory appeared on the scene, chemists had recognized many cases of isomerism among double-substituted benzene two distinct dihydroxy benzenes, two distinct ni-trophenols, two distinct nitrobenzoic acids, two distinct aminobenzoic acids, two distinct chlorobenzoic acids, and two distinct hydroxyben-zoic acids. Kekule mentioned the last of these in 1859, and declared what he called "oxybenzoic acid" to be an "isomer in the narrower sense" (i.e., a nonstructural isomer) of salicylic acid. He commented that there must be some unknown difference in the composition of the "atomic groups that are assumed as radicals in their formulas." ... 

LB, 1 188. Kekule s ambiguous type-style formula was probably intended to signify that "salicylous acid" is salicylaldehyde, which is indeed a structural isomer of benzoic acid. 

The active substance most often used in pyrotechnic whistles is gallic acid (3, 4, 5 trihydroxybenzoic acid). The potassium salts of benzoic acid of 2, 4, dinitrophenol and of picric acid (2, 4, 6 trinitro-phenol) and the sodium salt of salicylic acid (o-hydroxy benzoic acid) are also effective. They are combined with potassium chlorate, perchlorate, or nitrate (Formulas 156—160). 

Definition Ester of amyl alcohol and salicylic acid Empirical C12H16O3 Formula C6H4OHCOOC5H11 Properties Water-wh. liq., orchid-like odor sol. in alcohol, ether insol. in water, glycerol m.w. 208.26 dens. 1.053 b.p. 277-278 C flash pt. > 230 F ref. index 1.5050-1.5080 (20 C)... 

Bismuth suboxide. See Bismuth hydroxide Bismuth subsalicylate CAS 14882-18-9 EINECS/ELINCS 238-953-1 Synonyms Basic bismuth salicylate Bismuth salicylate basic Bismuth (III) salicylate basic (2-Hydroxybenzoato-0 )-oxobismuth 2-Hydroxybenzoic acid bismuth (3+) salt basic Oxy (salicylato) bismuth Salicylic acid, basic bismuth salt Salicylic acid, bismuth basic salt Empirical C7HsBi04 Formula HOC6H4COOBiO Properties Wh. cryst. powd. odorless tasteless sol. in acids, alkalis insol. in water, alcohol, ether stable in air dec. by boiling water, alkalis to more basic salt m.w. 362.10... 

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