Role playing demonstrations

Role playing demonstrations are an important way to help define the behavioral steps of a procedure. A volxmteer acts out the behaviors while observers attempt to determine whether each of the designated steps of the activity was "safe" or "at risk." Suppose, for example, your work group was interested in improving stair safety and decided the... 

The development of neutron diffraction by C G Shull and coworkers [30] led to the detennination of the existence, previously only a hypothesis, of antiferromagnetism and ferrimagnetism. More recently neutron diffraction, because of its sensitivity to light elements in the presence of heavy ones, played a cmcial role in demonstrating the importance of oxygen content m high-temperature superconductors. 

The deleterious effect of some fat substitutes has been demonstrated in cake frosting (27) the result is an unacceptable frosting, filled with air bubbles. In another example, some low fat cheeses are quite acceptable when cold, but when heated result in a product texture that changes to a sticky, gummy mass. Attempts to replace fat must be viewed as a total systems approach (28,29). It is likely that no one material will replace fats in food rather, replacement will consist of mixtures with each ingredient addressing one or more of the roles played by fats in food. 

Role playing. Very effective for demonstrating management techniques, simulating system cc nponents, and stimulating interaction. Requires a competent facilitator cannot be reproduced. 

Role plays or case studies for participants in which they can demonstrate the skills and attitudes required for their role. 

Environmental catalysis has its potential in improving innovations in the field of catalysis and highlighting the new directions for research driven by market, social, and environmental needs. Therefore, it can be concluded that environmental catalysis plays a key role in demonstrating the role of catalysis as a driver of sustainability by improving the quality of life and protecting human health and the environment... 

The crystalline complex of PIB with either / or y-CD was insoluble even in boiling water, but it was solubilized when urea was added to the suspension and heated. This fact demonstrates the important role played by hydrogen bonding played in stabilizing the complex. The X-ray diffraction pattern for the complex of PIB with y-CD was entirely different from that for uncomplexed y-CD and suggested an extended column structure. 

Figure 12.3 Rigid and flexible molecular interaction field maps with the hydrogen probe in the active-site cavity for CYP2C9 and UCT2B7 enzymes. It is worth noting that, with flexible side chains, the overall cavity volume changes considerably. This demonstrates the important role played by MIF-flexibility calculations in enzyme-substrate recognition.

Enzymatically active PARP molecules have also been found involved in transcription in undamaged cells. Recent research on Drosophila has demonstrated that active puff loci are rich in PARPl and ADPR polymers, this being the necessary condition to induce chromatin decondensation and gene expression [159]. Mechanism of PARPl-mediated puffing and chromatin remodeling reinforces the idea previously suggested by Althaus to explain the role played by PARPl in DNA repair [160]. 

The approximate validity of Eq. (12.9) highhghts the leading role played by the reorganizational energies but also vividly demonstrates the importance of using the correct intrinsic bond energies, whose values range from 69.63 to 89.1 kcal/mol... 

Results from these experiments indicate that the aromatic stacking interaction between complementary strands is probably not the factor responsible for the stabilization of the cross-linked product in aqueous media. Instead, the critical role played by interstrand H bonding in the stabilization of products 19-20 (and similarly 21-22) was clearly demonstrated by the high sequence specificity of the cross-linking reactions, as well as by the behavior of control strands 24 and 25 in the presence of 20. 

A series of pyrazolo[3,4-, pyridazinones 430 and analogues, potentially useful as peripheral vasodilators, were synthesized and evaluated as inhibitors of PDE5 extracted from human platelets. Several of them showed ICso values in the range 0.14-1.4 pM. A good activity and selectivity profile versus PDE6 was found for compound 430 (6-benzyl-3-methyl-l-isopropyl-4-phenylpyrazolo[3,4-r/]pyridazin-7(6/7)-one). Structure-activity relationship studies demonstrated the essential role played by the benzyl group at position 6 of the pyrazolopyridazine system. Other types of pyridazinones fused with five- and six-membered heterocycles (pyrrole, isoxazole, pyridine, and dihydropyridine), as well as some open-chain models were prepared and evaluated. Besides the pyrazole, the best of the fused systems proved to be isoxazole and pyridine <2002MI227>. 

VO2 and Ti02) leads to the formation of extended defects, i.e. CS planes, rather than to point defects. In the early literature reports, the definition of CS involved the removal of a complete sheet of anion sites to form an extended CS plane defect (Wadsley 1964, Anderson and Hyde 1967). Consequently, the role played by true point defects in non-stoichiometric oxides was not obvious from these earlier reports and answer to this was sought by Anderson (1970, 1971), Anderson et al (1973) (1.13.2). However, although this definition of CS is a convenient one, the situation is not so straightforward as we now demonstrate. 

Work along these lines could give a better understanding of the role played by ions in the radiation chemistry of polymers. The fact that ions can induce chemical reactions in irradiated organic solids is clearly demonstrated by the polymerization of certain crystalline monomers which are known to polymerize only when treated with ionic catalysts (3). 

---