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Rheumatoid disease, stroke

Congestive heart failure Hypertension Deep vein thrombosis Coronary artery disease Stroke Diabetes Insulin resistance Glucocorticoid imbalance Gall bladder disease Hypercholesterolemia Hypertriglyceridemia Gout Pancreatitis Liver disease Osteoarthritis Rheumatoid arthritis Bone fractures Lower back pain Carpal tunnel syndrome Depression Pain... [Pg.840]

Preventable Diseases Leading causes of death in the United States—heart disease, stroke, cancer, rheumatoid arthritis, and diabetes—that are often the direct result of poor lifestyle choices. [Pg.909]

Besides drugs, other conditions that can lead to mouth dryness are radiation against the neck, fever, concomitant diseases such as rheumatoid arthritis and other connective tissue diseases (scleroderma, sicca syndrome), Parkinson s disease, numeral psychiatric conditions and stroke with paralysis, dysphagia, neglect or oral apraxia. Damage to the mouth can arise due to drug treatment through different mechanisms and here are some examples. [Pg.52]

Aging (skin and other tissues), myocardial infarct or stroke, inflammation, rheumatoid arthritis, atherosclerosis, pulmonary disorders (asthma and chronic obstructive pulmonary diseases), radiation injury, organ transplant rejection, psoriasis, hypertension, AIDS, multiple types of cancer, neuro-degenerative diseases (Parkinson s), diabetes, muscular dystrophy... [Pg.62]

The sahcylates are useful in the treatment of minor musculoskeletal disorders such as bursitis, synovitis, tendinitis, myositis, and myalgia. They may also be used to relieve fever and headache. They can be used in the treatment of inflammatory disease, such as acute rheumatic fever, rheumatoid arthritis, osteoarthritis, and certain rheumatoid variants, such as ankylosing spondylitis, Reiter s syndrome, and psoriatic arthritis. However, other NS AIDS are usually favored for the treatment of these chronic conditions because of their lower incidence of GI side effects. Aspirin is used in the treatment and prophylaxis of myocardial infarction and ischemic stroke. [Pg.429]

The inflammation response to tissue injury involves infiltration of damaged areas by leukocytes from the blood stream (1-4). Unregulated extravasation of leukocytes can result in inflammatory disorders such as reperfusion injuries, stroke, psoriasis, rheumatoid arthritis and respiratory diseases. An early step in the cascade of events leading to influx of leukocytes is the recognition of the tetrasaccharide sLex 1 (found on the terminus of leukocyte surface glycoproteins), by E, P and L selectins that are expressed by endothelial cells... [Pg.121]

Perhaps the application for human stem cells with the most potential is the generation of cells and tissues for the cell-based therapies. The demand for donated organs and tissues far outweighs the supply. Stem cells could possibly be directed toward the production of replacement cells and tissues to treat Parkinson s disease, Alzheimer s disease, spinal cord injury, stroke, burns, heart disease, diabetes, osteoarthritis, and rheumatoid arthritis. [Pg.24]

The Health Outcomes Institute has developed and validated several outcome instruments that can be used to 11 evaluate patient outcomes following interventions by pharmacists. These include hypertension/lipids, angina, asthma, chronic obstructive pulmonary disease, chronic sinusitis, hip replacement, hip fracture, depression, low back pain, osteoarthritis, alcohol abuse, stroke, rheumatoid arthritis, and prostatism (Appendix 4). The Health Outcomes Institute is located at 2001 Killebrew Drive, Suite 122, Bloomington, MN 55425 telephone (612) 858-9188. [Pg.805]

More narrow SNP scans were very successfully performed for candidate susceptibility loci. Examples of strong association exist for ischemic stroke, migraine, psoriasis, rheumatoid arthritis or Crohn s disease. The investigation of known loci by following the haplotype strategy has already been fruitful for brain-derived neurotrophic factor (BDNF) and obsessive compulsive disorder [13], for RET and Hirsch-spmng s disease [14], for apoHpoprotein E (APOE) and Alzheimer s disease [15], and for TAU and late-onset Parkinson s disease [16]. [Pg.92]

Fig. 10) [165], The Cytel corporation in San Diego has been able to scale-up this process for the routine production of kilogram quantities in each run of reactions [144]. The sialyl Le tetrasaccharide and its analogs are of pharmaceutical interest in the context of new treatments for chronic inflammatory diseases (psoriasis, rheumatoid arthritis), tumors, and tissue injuries following a heart attack, stroke, or organ transplant. Sialyl Lex and its analogs are therefore enthusiastically pursued by several pharmaceutical companies. Strategies for the solid-phase chemoenzymatic synthesis of glycopeptides (and glycolipids) containing sialyl Lex have also been designed and reported [144,156, and references therein]. Fig. 10) [165], The Cytel corporation in San Diego has been able to scale-up this process for the routine production of kilogram quantities in each run of reactions [144]. The sialyl Le tetrasaccharide and its analogs are of pharmaceutical interest in the context of new treatments for chronic inflammatory diseases (psoriasis, rheumatoid arthritis), tumors, and tissue injuries following a heart attack, stroke, or organ transplant. Sialyl Lex and its analogs are therefore enthusiastically pursued by several pharmaceutical companies. Strategies for the solid-phase chemoenzymatic synthesis of glycopeptides (and glycolipids) containing sialyl Lex have also been designed and reported [144,156, and references therein].
FP has a history of cardiovascular disease, having survived a myocardial infarction that occurred in his mid-50s and, more recently, a stroke. Currently, he is on extended-release diltiazem (Cardiazem, 420 mg q.i.d.) and betaxolol HCI (Kerlone, 10 mg q.i.d.) for chronic stable angina coupled with hypertension. He also takes one baby aspirin each day. FP is troubled by rheumatoid arthritis, for which he takes diclofenac (Voltaren, 50 mg t.i.d.), and he has a documented allergy to sulfonamides. [Pg.792]


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Rheumatoid

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