Rheum-emodin

Emodin (= Archin Frangula emodin Frangulic acid Rheum emodin 1,3,8-Trihydroxy-6-methyl-9,1 Clan thracenedione) (anthraquinone)... 

The main anthraquinone-containing plants are cascara sagrada Rhamnus purshiana), senna, rhubarb, aloes, dock and St John s wort. Rheum-emodin is a typical simple anthraquinone from rhubarb root Rheum palmatum). 

Emodin, l,3,8-trihydroxy-6-methylanthraquinone, is an anthraquinone dye which occurs mostly as a rhatrmoside (see Frangulin) in various Rhamnus, Rheum and Cassia species. It is a major dye component extracted from the bark of Cassia fistula L. Also known as frangula emodin and rheum emodin Merck Index, 1996 Schweppe, 1992). 

Rheum officinale Baill. R. koreanum Nakai R. palmatum L. R. tanguticum Maxim R. undulatum L. Tai Huang (Rhubarb) (rhizome) Anthraquinones, chrysophanol, emodin, physcion, aloe-emodin, rhein, chrysophenol, rheum tannic acid, gallic acid, calechin, bianthraquinonyl, sennosides (R. undulatum also contains rhaponticin).1 33 236,510 This herb may be toxic. Potent laxative, antibacterial, anthelmintic, anticancer, stimulate the large intestine and increase the movement of luminal contents toward the anus, resulting in defecation. Antispasmodic, choleretic, hemostatic, diuretic, lower blood pressure, lower cholesterol level. 

N.A. Rheum tanguticum L. Cinnamic acid, gallic acid, emodin, rhein, rhein anthrones, catechin, anthraquinone compounds, tannin.99-100-107 Treat diarrhea, stimulate appetite, chronic constipation, laxative, cathartic. 

Emodin (l,6,8-trihydroxy-3-methylanthraquinone), the active principle of Polygonum cuspidatum (Polygonaceae), was reported to be an inhibitor of the p56 -PTK activity from bovine thymus, with an IC50 of 18.5 pM. When the hydroxyl functions at C-6 or C-8 were blocked by methylation or glycosylation, respectively, the effect disappeared. The inhibition was competitive with respect to ATP and non competitive with respect to the substrate [64]. In a bioassay-guided separation of the anthraquinones found in rhizomes of another Polygonaceae species, rhubarb Rheum... 

Substances Aglykones of an extract from the root of Rheum officinale 191 1. Position of start with the non chromatographed matrix and the glycosides 2. rhein 3. physeione 4. emodine 5. chrysophanol... 

For example, emodin, Fig. (4) is an active component from the root and rhizome of Rheum palmatum L. that has been reported to exhibit antitumor effects, but the mechanism is not known. Several studies demonstrated that emodin induces cell apoptosis in human lung squamous carcinoma cell line... 

In a study on different anthraquinones from Rheum palmatum, Chen et al. [161] found that emodin, but not physion or chrysophanol, induced apoptosis in HL-60 cells though activation of the caspase 3 cascade. The... 

Rheopearl KL. See Dextrin palmitate Rheum emodium. See Emodin Rheum palmatum Rheum palmatum extract Rheum palmatum root extract. See Rhubarb (Rheum palmatum) extract Rhodacal 60BHF, Rhodacal 70/B. See Calcium dodecylbenzene sulfonate Rhodacal 301-10, Rhodacal 301-10F, Rhodacal 301-1 OP. See Sodium C14-16 olefin sulfonate... 

Figure 25 Separation of anthraquinone aglycones from Rheum palmatum. Solvent system light petroleum (40-60 C)-ethyi acetate-formic acid (75 25 1). Stationary phase silica gel 60 G (Merck, lab. prepared, 0,5 mm). Developing distance 18 cm. Detection absorbance at 420 nm. Peak identities (1) chrysophanol (2) physcione (3) emodin (4) rhein (5) aloe-emodin.

Xiong HR, Luo J, Hou W et al (2011) The effect of emodin, an anthraquinone derivative extracted from the roots of Rheum tanguticum, against herpes simplex virus in vitro and in vivo. J Ethnopharmacol 133 718-723... 

Emodin is found mostly as a rhamnoside in various Rhamnus, Rheum and Cassia species. 

L. R. saxatilis Jacq. Rheum spp. R. palmatum Polygonaceae Tbllow-berries Rhubarb Rhamnotaimic acid Khamnin brangulmj Rhein Ph5rsicon, Palmitin A,B,C,D Sennidin Chrysophanol Chrysophanic acid Emodin Aloe-emodin (e.g. Harley, 1982) R. infectoria... 

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