Results recurrence

Standard therapy includes laser ablation and excision producing good short-term results. Recurrences often require repeated treatments which may cause vulvar damage by scar formation. 

Dry and hot periods promote monoterpene volatilization from soil and may also increase flammability. As a result, recurrent dry periods may lead to more frequent and more rapidly spreading bushfires when monoterpene-rich soil supports the spread of fire, again removing competitors. 

Pgf values of the various distributions with respect to the counts of monomer units, bonds, or unreacted functional groups can be obtained from Eq. (98) by setting equal to one the molecular weight of the species in question and to zero the molecular weights of all the other species. Analytical inversion by computing derivatives with respect to dummy Laplace variables on s = 0 is feasible with the simplest chemical systems, for which the resulting recurrence formulae are not too complex, as happens with the Stockmayer distribution. 

If a response occurs, treatment intervals may be lengthened to every two weeks, then three weeks, and then monthly. Patients who respond usually remain at least on monthly therapy. Discontinuation of gold therapy maintenance may result in recurrence of arthritic symptoms, which may not remit even with reinstitution of gold therapy. Auranofin (22), adrninistered in 3-mg amounts twice daily or 6 mg once daily, should be continued for at least six months, assuming a favorable response. 

Asthma affects 3—5% of the population and is one of the most common chronic illnesses (7—9). Both the frequency and severity of asthma appear to be increasing (10—13). Acute, severe asthma has the potential to be fatal. The disease may first appear ia childhood and iadividuals so affected can suffer recurrent episodes throughout their Hves or they may "outgrow" the condition at puberty. On the other hand, there is also adult-onset asthma. These people show no symptoms as children or as young adults, but suddenly develop symptoms later ia life. There have been many reports of bronchial infections preceding the appearance of asthma. However it is not known whether these infections contributed to the development of the disease or whether iadividuals who are already predisposed to asthma ate more likely to experience bronchospasms as a result of a bronchial infection (14). 

Fohc acid is safe, even at levels of daily oral supplementation up to 5—10 mg (97). Gastrointestinal upset and an altered sleep pattern have been reported at 15 mg/day (98). A high intake of foHc acid can mask the clinical signs of pernicious anemia which results from vitamin deficiency and recurrence of epilepsy in epileptics treated with dmgs with antifolate activity (99). The acute toxicity (LD q) is approximately 500 and 600 mg per kg body weight for rats and mice, respectively (100). 

The antiviral mechanism of action of acyclovir has been reviewed (72). Acyclovir is converted to the monophosphate in herpes vims-infected cells (but only to a limited extent in uninfected cells) by viral-induced thymidine kinase. It is then further phosphorylated by host cell guanosine monophosphate (GMP) kinase to acyclovir diphosphate [66341 -17-1], which in turn is phosphorylated to the triphosphate by unidentified cellular en2ymes. Acyclovir triphosphate [66341 -18-2] inhibits HSV-1 viral DNA polymerase but not cellular DNA polymerase. As a result, acyclovir is 300 to 3000 times more toxic to herpes vimses in an HSV-infected cell than to the cell itself. Studies have shown that a once-daily dose of acyclovir is effective in prevention of recurrent HSV-2 genital herpes (1). HCMV, on the other hand, is relatively uninhibited by acyclovir. 

A number of alarm systems suffer from repeated false alarms. This may be due to the poor design and selection of detectors, inadequate standards of installation or preventative maintenance, and faulty operation of the system by key holders. Recurrent false calls will quickly discredit any system and may result in the withdrawal of police response to any alarm activation. 

The key result in this section will be the derivation of linear recurrence relations for 7)v,p in terms of 7j,p, for j < n [jen 88a]. We begin by introducing an invariance matrix, whose powers correspond to the lattice sizes on which f> is defined. 

Stimulation of mAChRs also results in the activation or inhibition of a large number of ion channels [5]. For example, stimulation of Mi receptors leads to the suppression of the so-called M current, a voltage-dependent Recurrent found in various neuronal tissues. M2 receptors, on the other hand, mediate the opening of cardiac Ikcacii) channels, and both M2 and M4 receptors are linked to the inhibition of voltage-sensitive calcium channels [5]. 

Promoting an Optimal Response to Therapy When administering an anticonvulsant, the nurse must not omit or miss a dose (except by order of the primary health care provider). An abrupt interruption in ther-apy by omitting a dose may result in a recurrence of the seizures. In some instances, abrupt withdrawal of an anticonvulsant can result in status epilepticus. 

The requirement a << 1 necessitates making some modifications for stability of this or that difference scheme. As a final result of minor changes, the recurrence formulae have the representations... 

Intraarterial infusion of microspheres containing adriamycin was used for the local treatment of breast cancer and recurrent breast cancer with liver metastases (123). A reduction in tumor size was noted when the microspheres were injected into the internal and lateral thoracic arteries for treatment of the primary tumor. However, hepatic artery injection for liver metastases resulted in improvement in only one of three patients treated. 

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