Required toxicological tests for official approval of a pesticide

2 Required toxicological tests for official approval of a pesticide 

The risk assessment of pesticides used for plant protection is similar but not identical in most countries. The European Union (EU), Organization for Economic Co-operation and Development (OECD), and other international organizations have specified legal requirements for toxicity documentations. The following tests should be carried out  

Not all these tests may be required. If new data on toxicity are coming up, the approval may be withdrawn. Some countries (e.g., Norway) also require that the new pesticide be safer than or have other advantages compared with products already on the market. There may also be an approval period restricted to 5 years. Reapplication is necessary if marketing is to be continued. A fee must also be paid at the time of reapplication. This mechanism helps to keep the number of products on the market low. 

The assessment of these compounds and the establishment of an ADI (acceptable daily intake), to be explained later, or MRL (maximum residue limit) are carried out by an international committee of the WHO (Joint Meeting on Pesticide Residues). The World Health Organization publishes toxicological and ecotoxicological evaluations of potential environmental toxicants in the International Proceedings on Chemical Safety in the series Environmental Health Criteria.  

Sampling Collection Avoidance of cross-contamination is as important as ensuring that a representative sample is taken 

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