Cullen Report

The first safety cases prepared for the process industries were those developed for North Sea offshore oil and gas operations following the Piper Alpha disaster that occurred in the year 1988. The Cullen report (Cullen, 1990) that was written following that accident was highly critical of offshore operating practices and recommended that a safety case approach be implemented. The Seveso incident that occurred in Italy further prompted the increased use of safety cases. Since that time the use of safety cases has spread to other industries (such as mining and railway operations) and to other nations, primarily in Europe and Australasia. (It is notable that the safety case regime approach has not been taken up for offshore oil and gas operations in the Gulf of Mexico—instead a more prescriptive approach based on industry consensus standards is used.)... 

Mr. Wondrich said that he got the idea for rye whiskey dosed with Tabasco sauce from a book of hard-luck stories, Tales of the Ex-Tanks, which purports to be the minutes of the Harlem Club of Former Alcoholic Degenerates, written by Clarence Louis Cullen, a New York Sun reporter, and published in 1900. 

The original work on wet chemical functionalization of germanium was reported as early as 1962 by Cullen et al. (researchers in RCA labs) [105]. They exposed ethyl Grignard to a chloride-terminated Ge(lll) surface and used radiotracer studies with tritiated ethyl groups to show that ethylation of the surface occurs via formation of Ge—C bonds in a one-to-one ratio with surface atoms. Because the chlorination procedure used by the authors can lead to formation of mono-, di-, and trichloride species, there may be some uncertainty as to the Ge/C ratio. However, these surfaces did demonstrate hydrophobic behavior and stability in both atmosphere and aqueous solution. 

Although the reviewers listed above have provided many constructive comments and suggestions, they were not asked to endorse the conclusions or recommendations nor did they see the final draft of the report before its release. The review of this report was overseen by Mark Cullen, Yale University, appointed by the Division on Engineering and Physical Sciences, who was responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution. 

The safety of the medication system is the primary concern of every hospital pharmacist. Recently published reports of the incidence, causes, and cost of injury resulting from medication errors have led many hospitals to critically evaluate their quality assurance systems (Bates et al., 1996, 1997 Classen et al., 1997 Kohn, Corrigan, and Donaldson, 1999 Leape et al., 1991, 1995 Poon et al., 2006 Stelfox, et al., 2006). Written incident reports were once the standard for gathering information about medication misadventures. This method is now believed to lack sufficient completeness and reliability for identifying weaknesses in a medication system (Classen et al., 1991 Cullen et al., 1995 Leape, 1994, 2002 Leape et al., 1995). 

Cullen DJ, Bates DW, Small SD, et al. 1995. The incident reporting system does not detect adverse events. Joint Comm J Qual Improv 21 541. 

Dysbindin-1 proves to be a ubiquitous neuronal protein in the CNS under optimal immunohisto-chemical conditions. Those conditions include heat-induced epitope retrieval in EDTA (Pileri et al., 1997) and signal amplification using nickel sulfate (Cullen, 1994) or silver-gold (Teclemeriam-Mesbah et al., 1997). Virtually all neuronal populations appear to be immunoreactive for dysbindin-1 in the brain and the spinal cord (O Figure 2.2-13). As noted earlier, Iijima et al. (2009) reported that dysbindin-1 is found in... 

A mechanism proceeding via abstraction of a hydride ion by HFA with formation of isopropoxide ion as the initial step, followed by reversible addition of another molecule of HFA, has been proposed. The resulting anions combine with the McjSi cation to yield 1 and 2 (158). The 1 1 adduct of 1 with HFA reported by Cullen and Styan (7i) has been proved by Janzen and Willis (158) to be identical with 2. 

As noted earlier, the comparatively high vapour pressures of some (lower chlorinated) PCBs implies that they will partition principally to indoor air, and this provides a plausible explanation as to why comparatively little attention has been paid to their contamination of indoor dust. However, a review of the available evidence suggests that dust may contain substantial concentrations of PCBs. Table 7.3 summarises reported concentrations of XPCBs in indoor dust (Harrad et al., 2008a Tan et al., 2007b Vorhees, Cullen, and Altshul, 1999). In addition, a few other studies have reported concentrations of a limited... 

Charudattan, R., Freeman, T. E., Cullen, R. E., and Hofmeister, F. M. Technical Report A-84-5. US Army Engineer Waterways Experiment Station, Vicksburg, MS 1984. p. 30. 

Some studies have reported conservative behavior during estuarine mixing. In the unpolluted Krka Esmary of Yugoslavia, Seyler and Martin (1991) observed a linear increase in total arsenic with increasing salinity, ranging from 0.13 xgL in freshwaters to 1.8 JLgL offshore. Other studies however, have observed nonconservative behavior in estuaries due to processes such as diffusion from sediment pore waters, co-precipitation with iron oxides, or anthropogenic inputs (M. O. Andreae and T. W. Andreae, 1989 Andreae et al., 1983). The flocculation of iron oxides at the freshwater-saline interface as a result of increase in pH and salinity can lead to major decrease in the arsenic flux to the oceans (Cullen and Reimer, 1989). 

Concentration of antimony in mollusc shells found in the coastal waters of British Columbia, Canada, reported by Cullen and coworkers , are soft-shell clam from Hastin Arm 0.51 ppm, from Anyox 0.14ppm, gastropods 0.2-1.4ppm, butter clam Sb(III) 4.5, Sb(V) 114 ppb, bent-nose clam Sb(IIl) not detected, Sb(V) 35 ppb. 

W. Cullen, M. Kemppainen, H. Hanninen, K. Torronen, Report NUREG/CR-4121, MEA-2053 (1985). (Available from NTIS.) (National Technical Information Service). 

Cullen DJ. Severe anaphylactic reaction to penicillin during halothane anaesthesia. A case report. Br J Anaesth 1971 43(4) 410-12. 

TK Kirk, JW Koning, Jr., RR Burgess, M Akhtar, RA Blanchette, DC Cameron, D Cullen, PJ Kersten, EN Lightfoot, GC Myers, M Sykes, MB Wall. Biopulping A glimpse of the future Forest Products Laboratory Research Report FPL-RP523, 1993, 74 pp. 

DMA, As ) observed, and their mobility in soils studied (Garbarino et al. 2003, Rutherford etal. 2003). Arsenocholine was also reported to have growth-promoting effects in chickens (Cullen and Reimer 1989). 

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