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Remeron - Mirtazapine

Mirtazapine (Remeron). Mirtazapine is the newest of the atypical antidepressants. It mainly works by blocking the alpha-2 negative feedback receptor and thus increases norepinephrine and serotonin activity. In addition, mirtazapine blocks serotonin-2 and serotonin-3 receptors to produce a specific serotonin action like nefazodone. Mirtazapine is approved for the treatment of depression. Its use in the anxiety disorders is being studied. [Pg.58]

Figure 4.3 Remeron (mirtazapine), also a second generation antidepressant, is unrelated to any of the other antidepressants. Its chemical structure is shown here. Remeron acts directly on alpha-2 adrenergic receptors instead of inhibiting neurotransmitter uptake. Figure 4.3 Remeron (mirtazapine), also a second generation antidepressant, is unrelated to any of the other antidepressants. Its chemical structure is shown here. Remeron acts directly on alpha-2 adrenergic receptors instead of inhibiting neurotransmitter uptake.
Remeron (Mirtazapine). Organon USA Inc. US Prescribing information, June 2005. [Pg.70]

Mirtazapine Remeron Yes Tablet, disintegrating tablet (SolTab) 15 15-45 Once daily... [Pg.577]

Mirtazapine Remeron o2 antagonist, 5-FIT2 5-FIT3 antagonist... [Pg.250]

Mirtazapine (Remeron) is a newer antidepressant that also blocks 5-HT reuptake, but additionally has antagonistic effects at adrenergic o2, 5-HT2, and 5-HT3 receptors (Stahl 1998). Mirtazapine appears to have indirect agonistic effects on 5-HTlA receptors, which may contribute to its antidepressant effect (Berendsen and Broekkamp 1997). Nefazodone, as well, has SSRI and 5-HT2 antagonist effects. The 5-HT2 antagonist effects of these antidepressants is believed to be responsible for their lower incidence of sexual side effects (Nutt 1997). [Pg.251]

Atypical Antidepressants. The atypical antidepressants are not a true class in the same sense as SSRIs or TCAs. There is no unifying property to these antidepressants. Each of these antidepressants is actually a class unto itself that is structurally and functionally different from all other antidepressants. The atypical antidepressants include trazodone (Desyrel), bupropion (Wellbutrin), venlafaxine (Effexor), duloxetine (Cymbalta), nefazodone (Serzone), and mirtazapine (Remeron). [Pg.56]

A controlled trial of duloxetine (Cymbalta)—like venlafaxine a dual serotonin-norepinephrine reuptake inhibitor—in the treatment of GAD is currently underway. Anecdotal data suggests that nefazodone (Serzone) and mirtazapine (Remeron) may be effective in the treatment of GAD, though no controlled data is available. In addition, recent concerns regarding nefazodone and liver toxicity have limited this medication s utility. Please refer to Chapter 3 for more information regarding these antidepressants. [Pg.150]

Antidepressants. The most widely used psychiatric medicines with the broadest range of application in TBI patients are undoubtedly the SSRI antidepressants. They are well tolerated, unlikely to worsen any of the preexisting deficits associated with TBI, and offer relief from not only depression but also impulsivity and virtually all variants of anxiety in these patients. As such, SSRIs are the preferred first-line treatment for all anxiety disorders after TBI. Other newer antidepressants that also work (at least in part) by boosting serotonin activity, namely, mirtazapine (Remeron), nefazodone (Serzone), venlafaxine (Effexor XR), and duloxetine (Cymbalta) can also be considered, but they have not been well studied in patients with TBI. In... [Pg.347]

Blocking the norepinephrine alpha-2 receptor can also increase norepinephrine activity. The alpha-2 receptor provides feedback to the neurons to stop releasing norepinephrine and, for that matter, serotonin. By blocking the alpha-2 receptor, norepinephrine and serotonin are more readily released. The atypical antidepressant mirtazapine (Remeron) acts in part in this manner (see Table 13.2). [Pg.360]

Ruvoxamine (Luvox) Imipramine (Tofranil) Mirtazapine (Remeron, RemCTon SolTab) Nefazodone (Serzone) Nortriptyline (Aventyl, Pamelor)... [Pg.42]

Mirtazapine (Remeron) enhances both serotonergic and noradrenergic neurotransmission. By blocking presynaptic aj-adrenoceptors, mirtazapine causes release of norepinephrine. Indirectly, through noradrenergic modulation of serotonin systems, mirtazapine also causes increased release of serotonin. It is an antagonist... [Pg.388]

Norepinephrine-serotonin modulators Mirtazapine Remeron 15 15 5 7.5, 15, 30, 45, soltab 20... [Pg.14]

Mirtazapine [Remeron] Exact mechanism unclear may increase norepinephrine and serotonin activity by blocking inhibitory presynaptic autoreceptors Low incidence of sedative, anticholinergic, and cardiovascular side effects May cause agitation, anxiety, other mood changes... [Pg.83]

OFFICIAL NAMES Amitriptyline (Elavil), amoxapine (Asendin), bupropion (Wellbutrin), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), fluoxetine (Prozac), imipramine (Norfranil, Tofranil), isocarboxazid (Marplan), maprotiline (Ludiomil), mirtazapine (Remeron), nefazodone (Serzone), nortriptyline (Aventyl, Pamelor), paroxetine (Paxil), phenelzine (Nardil), protriptyline (Vivactil), sertraline (Zoloft), thioridazine (Mellaril), tranylcypromine (Parnate), trazodone (Desyrel), trimipramine (Sur-montil), venlafaxine (Effexor) the herb St. John s wort (Hypericum perforatum) is sold over-the-counter without prescription STREET NAMES Happy pills... [Pg.52]

Alpha2 antagonist + noradrenergic/ specific serotonergic Mirtazapine (Remeron)... [Pg.43]

See other pages where Remeron - Mirtazapine is mentioned: [Pg.263]    [Pg.11]    [Pg.459]    [Pg.246]    [Pg.675]    [Pg.60]    [Pg.263]    [Pg.11]    [Pg.459]    [Pg.246]    [Pg.675]    [Pg.60]    [Pg.285]    [Pg.795]    [Pg.30]    [Pg.135]    [Pg.380]    [Pg.225]    [Pg.386]    [Pg.395]    [Pg.223]    [Pg.80]    [Pg.689]    [Pg.751]    [Pg.782]    [Pg.71]   


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Mirtazapine

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