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Regeneration Bone marrow

B26. Brody, S., and Thorell, B., Ribonuclease and desoxyribonuclease activities in normal and regenerating bone marrow homogenates. Biochim. Biophys. Acta 26, 579-585 (1957). [Pg.199]

Since the majority of AML patients lack a HLA-identical donor, investigators began to consider the use of the patient s own bone marrow, obtained while in CR, as a source of hematopoietic regeneration. However, relapse continues to be a problem... [Pg.1410]

Branemark PI, Breine U, Johansson B, Roylance PJ, Rockert H, Yoffey JM (1964) Regeneration of bone marrow. Acta Anat 59 1 46. [Pg.308]

Orlic, D. (2003). Adult bone marrow stem cells regenerate myocardium in ischemic heart disease. Ann N Y Acad Sci. 996, 152-157. [Pg.122]

Vassilopoulos G, Wang PR, Russel DW (2003). Transplanted bone marrow regenerates liver by cell fusion. Nature 422 901-904. [Pg.134]

Other effects were keratinized squamous metaplasia of the trachea (4000ppb) dose-related increases in tracheitis and desquamation of the tracheal epithelium, and bronchitis, desquamation, and regeneration of the bronchial epithelium (100, 400, and 4000 ppb) bone marrow erythropoietic hyperplasia (males, 4000ppb) testicular atrophy (males, 4000 ppb) and degenerative changes in the convoluted tubules of the kidneys. ... [Pg.379]

Animal studies indicate that the primary toxic effect of uranium exposure is on the kidney, with particular damage to the proximal tubules. Functionally, this may result in increased excretion of glucose and amino acids. Structurally the necrosis of tubular epithelium leads to formation of cellular casts in the urine. If exposure is insufficient to cause death from renal failure, the mbular lesion is reversible with epithelial regeneration. Although bone is the other major site of deposition, there is no evidence of toxic or radiocarcinogenic effects to bone or bone marrow from experimental studies. ... [Pg.723]

Kligerman 1984 (bone marrow, alveolar macrophages, and regenerating liver cells)... [Pg.60]

The identification of a direct cardiac precursor within the bone marrow cell population opens up a vast number of possibilities for the field of cardiac regeneration. In theory, in vitro expansion of this type of cell would be therapeutically attractive. [Pg.102]

In the Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI) trial, patients were randomized to receive either bone marrow-derived... [Pg.112]

Ferrari G, Cusella-De Angelis G, Coletta M, Paolucci E, Stornaiuolo A, Cossu G, Mavilio F. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998 279 1528-1530. [Pg.123]

Orlic D, Kajstura J, Chimenti S, Jakoniuk I, Anderson SM, Li B, Pickel J, McKay R, Nadal-Ginard B, Bodine DM, Leri A, Anversa P. Bone marrow cells regenerate infarcted myocardium. Nature 2001 410 701-705. [Pg.123]

Stamm C, Westphal B, Kleine HD, Petzsch M, Kittner C, Klinge H, Schumichen C, Nienaber CA, Freund M, Steinhoff G. Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet 2003 361 45 6. [Pg.126]

Meyer GP, WoUert KC, Lotz J, Steffens J, Lippolt P, Fichtner S, Fleckner FI, Schaefer A, Arseniev L, Hertenstein B, Ganser A, Drexler H. Intracoronary bone marrow cell transfer after myocardial infarction eighteen months follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 2006 113 1287-1294. [Pg.127]

Orlic, D., J. Kajstura, S. Chimenti, I. Jakoniuk, S.M. Anderson, B. Li, J. Pickel, R. McKay, B. Nadal-Ginard, D.M. Bodine, A. Leri, and P. Anversa, Bone marrow cells regenerate infarcted myocardium. Nature, 2001. 410(6829) 701-5. [Pg.412]

Several recent discoveries have shifted the paradigm for myocardial regeneration and have fueled enthusiasm for a new frontier in the treatment of cardiovascular disease with stem cells. Fundamental to this emerging field is the cumulative evidence that adult bone marrow stem cells can differentiate into a wide variety of cell types, including cardiac myocytes and ECs. This phenomenon has been termed stem... [Pg.400]

Abbreviations AMI, acute myocardial infarction BM-MNC. bone marrow mononuclear cell BOOST, bone marrow transfer to enhance ST-elevation infarct regeneration CPC, circulating progenitor cells HF, heart failure LV, left ventricle LVED, left ventricular end-diastolic diameter LVEDV, left ventricular end-diastolic volume LVER left ventricular ejection fraction Ml. myocardial infarction TOPCARE-AMI, transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction. Source From Ref. 21. [Pg.423]

Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium, Nature 2001 410 701-705. [Pg.436]

Kuethe F Richartz BM, Sayer HG, et al. Lack of regeneration of myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans with large anterior myocardial infarctions, Int J Cardiol 2004 97 123-127. [Pg.437]

Vanderheyden MMS, Vandekerckhove B, De Bondt R et al. Selected intracoronary CD 133 + bone marrow cells promote cardiac regeneration after acute myocardial infarction. Circulation 2004 I 10 324-325. [Pg.437]

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