Raspberry ellagic acid

ANCos B DE, GONZALES E M and CANO M p (2000) Ellagic acid, vitamin C, and total phenolic contents and radical scavenging capacity affected by freezing and frozen storage in raspberry fruit , J Agric Food Chem, 48 (10) 4565-70. 

Zafrilla P, Ferreres F and Tomas-Barberan FA. 2001. Effect of processing and storage on the antioxidant ellagic acid derivatives and flavonoids of red raspberry (Rubus idaeus) jams. J Agric Food Chem 49(8) 3651-3655. 

Ellagic acid is an astringent, hemostatic, antioxidant, antimutagenic, and possibly an antineoplastic agent from strawberries, raspberries, grapes, walnuts, and pecans. Its human dietary role in cancer prevention is uncertain and in planta function is unknown. 

A Rommel, RE Wrolstad. Ellagic acid content of red raspberry juice as influenced by cultivar, processing, and environmental factors. J Agric Food Chem 41 1951-1960, 1993. 

Ellagic acid has been reported to be present in berries, particularly raspberries (Rubus idaeus), strawberries, and blackberries [Amakura et al., 2000]. However, free ellagic acid is normally present in low levels in berries that more commonly contain ellagitannins, such as sanguiin H-6 and lambertianin C, which release ellagic and gallic acid when treated with acid (Fig. 1.26) [Mullen et al., 2002],... 

Figure 1.26 Ellagitannins and trace amounts of gallic acid and ellagic acid occur in raspberries.

Mullen, W., Yokota T., Lean M.E., Crozier, A. 2003. Analysis of ellagitaimins and conjugates of ellagic acid and quercetin in raspberry fruits by LC-MSn. Phytochem. 64 617-624. 

Red raspberries contain dense contents of ellagic acid, ellagitannins, and several other polyphenols under active research for potential health benefits as anti-inflammatory factors. These phenolic compounds have importance in research on diseases that start first with inflammation, such as cancer, chronic arthritis, Alzheimer s disease, diabetes, and obesity. In research done at Cornell University, scientists studying four cul-tivars of red raspberry identified differences in polyphenol content that were directly related to the color intensity of the respective juices. The color of the juice correlated well to the anthocyanin contents of each raspberry cultivar. In the same studies, proliferation of human liver cancer cells—as part of a laboratory test of potential anticancer activity— was significantly suppressed by the raspberry polyphenols. 

FIGURE 3.9 Flow diagram for juice processing by a standard technique. [Source Reprinted with permission from Rommel, A. and Wrolstad, R.E. 1993. Ellagic acid content of red raspberry juice as influenced by cultivar, processing and environmental factors, J. Agric. Food Chem. 41(11) 1951-1960. Copyright 1993 American Chemical Society.]... 

Hydroxybenzoic acids Ellagic acid Gallic acid Strawberry, raspberry, grapes, longan seed, and pomegranate [8,9]... 

Stoner GD, Sardo C, Apseloff G, et al. Pharmacokinetics of anthocyanins and ellagic acid in healthy volunteers fed freeze-dried black raspberries daily for 7 days. JCIP. 2005 45 1153-1164. 

Gonzalez-Barrio R, Edwards CA, Crozier A. Colonic catabolism of ellagitannins, ellagic acid, and raspberry anthocyanins In vivo and in vitro studies. Drug Metab Dispos. 2011 39 1680-1688. 

Black raspberry 980 Ellagic acid, quercetin 5-O-rutinoside... 

Ellagic acid and ellagitannins Blackberries, raspberries, strawberries, walnuts, pomegranates Antiproliferative, antioxidant... 

Ellagic acid Pomegranate, raspberries, cranberries, Terminalia chebula fruit, pecans, and walnuts Strengthens the immune system, anticancer, induces apoptosis of cancer cells and suppresses angiogenesis, prevents heart disease and liver fibrosis, promotes wound healing, prevents the binding of carcinogens to DNA [38]... 

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