Ras gene mutation

Boissel, N., Leroy, H., Brethon, B., Philippe, N., de Botton, S., Auvrignon, A., Raffoirx, E., Leblanc, T., Thomas, X., Hermine, 0., et al. (2006) Incidence and prognostic impact of c-Kit, FLT3, and Ras gene mutations in core binding factor acute myeloid leukemia (CBE AML). 

HusgafVel-Pursiainen K, Ridanpaa M, Anttila S, et al. 1995. p53 and ras Gene mutations in lung cancer Implications for smoking and occupational exposures. J Occup Environ Med 37 69-76. 

Zhu, D., Keohavong, P., Finkelstein, S., Swalsky, R, Bakker, A., Weissfeld, Sri vasts va, S., and Whitbide, T. L. (1997). K-ras gene mutations in normal colorectal tissues from K-ras mutation-po-sitive colorectal cancer patients. CapiCtfr Res. 57, 2485-2492... 

Suzuki Y, Orita M, Shiraishi M, Hayashi K, Sekiya T. Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene 1990 5 1037-43. 

Chang, Y.-J., C. Mathews, K. Mangold, K. Marien, J. Hendricks and G.S. Bailey. Analysis of ras gene mutations in rainbow trout liver tumors initiated by aflatoxin B1. Mol. Carcinog. 4 112-119, 1991. 

Moskaluk CA, Hruban RH, Kern SE. pl6 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma. Cancer Res. 1997 57 2140-2143. 

Tada M, Omata M, Ohio M. Ras gene mutations in intraductal papillary neoplasms of the pancreas. Analysis in five cases. Cancer. 1991 67 634-637. 

Ajiki T, Fujimori T, Onoyama H, et al. K-ras gene mutation in gall bladder carcinomas and dysplasia. Gut. 1996 38 426-429. 

Yamazaki K, Hanami K, Nagao T, Asoh A, Sugano I, Ishida Y. Increased cyclinDl expression in cancer of the ampula of Vater relevance to nuclear beta-catenin accumulation and K-ras gene mutation. Mol Pathol. 2003 56 336-41. 

In human liver angiosarcomas associated with occupational exposure to vinyl chloride, Marion et al. (1991) found that 5 out of 6 tumours contained a Ki-ras gene activated by a GC—>AT transition at the second base of codon 13. Ras gene mutations in vinyl chloride-induced liver tumours are carcinogen-specific but vary with cell type and species (Boivin-Angele et al. 2000). 

Fig. 2 Detection of K-ras gene mutations in CRC by Tag arrays B. Bead-Based Method...

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